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Does P.O.I.S. affect Female surely no, so that support that O. decreases some thing in the body and what is it??please let me knowwwwww.!!!!
Hi tantalus,"Pois and isolation even in the own group". Just curious: Who promised you (and the other guys) in 2004 to be united?Thanks in advance!
Quote from: Druid Getafix on 26/06/2012 09:47:27Hi tantalus,"Pois and isolation even in the own group". Just curious: Who promised you (and the other guys) in 2004 to be united?Thanks in advance!sorry, but I dont want to tell this. I just wanted to explain my urge to meet my palls, and my dissapointment. But i learned something by your question, could better not have mentioned it. was not really functional. thanks for the lesson.On the other hand... I can in a way understand the own legitimate reasons to not bring us together. But extreme sad i was and be until now. Yes. If the person who recognises himself in this reads this to, its i hope enough stimulus to promise this never again.not any more questions?....I am disappointed;>) Or did I do the rest of my letter so well?
p.s. the point is .....when you would get an injection with sperm as a first test( to see IF you react at all) you would get a much to strong alarm effect. Thats why I had e problems with the word combination >intradermal test<I hope my Flintstone english is understandable for you both.
So why would this be related to POIS? Simply because during an O we produce prolactin. Too much or too little would be a problem and would likely indicate a problem with balancing PGE2 levels.
Quote from: kurtosis on 24/06/2012 12:54:12So why would this be related to POIS? Simply because during an O we produce prolactin. Too much or too little would be a problem and would likely indicate a problem with balancing PGE2 levels.I reviewed the data on prolactin after reading your post kurtosis, and I had to pause: prolactin has been tied to the refractory period (period of tiredness/relaxation) by *repressing dopamine*. This caught my attention as dopamine neurotransmission is responsible for so many of the functions we complain are not working well. What if POIS sufferers have a more powerful prolactin surge than most men? What if our bodies don't react to the depletion of dopamine like others?Study on male who presents no prolactin creation upon orgasm, thus able to "O" and stay erect for many ejaculations in a row: http://www.nature.com/ijir/journal/v14/n2/full/3900823a.htmlAnd to tie up more lose ends, what if prolactin could help explain our immune system issues and our successes with that treatment approach? I feel there is too much evidence in support of an immunological theory to not include it in my thinking.From the Wiki page on prolactin: "Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system." Right there. We have had so many people thinking about histamines and how most allergies the public talk about are being powered by histamines. Yet, it has been explained that there are different levels of immune response and that POIS probably operates on the cytokine level and out of the reach of anti-histamines. Well, what if our own hormone is doing double duty, starving our system of the dopamine needed to operate our nervous system well AND is causing the inflammation/flu-like symptoms we have been discussing for so long?Could Waldinger's desensitization treatments not be calming down an antibody attack, but actually instead be sensitizing his patients to the presence of prolactin so as to buffer against its dopamine fighting actions?And what about Niacin? Quoting you kurtosis: "Simply because during an O we produce prolactin. Too much or too little would be a problem and would likely indicate a problem with balancing PGE2 levels. " I didn't see a reference there, but I see it as the only other loose end to tie. Might the flushing response to niacin somehow set us up for metabolizing prolactin (perhaps less so on our sexual system where it's needed, more so all over the whole body)?This has got me really interested!
About female Pois, there are strange testimonies describing the same problem... without men.About astaxanthin, it should work but it didn't for me . Maybe should i take 3 caps a day during several weeks.
Hello tantalus, my POIS symptoms used to last between 4-5-6 days. I got pretty bad cognitive problems_ Brain fog, lethargy, difficulty concentrating, simple speech and so on... Have you tried niacin? A good use of niacin could block completely my POIS symptoms, and i have been able to overcome this nightmare -> In the sense that is not a -big- problem in my daily life, tough i am going to experience the same POIS symptoms that in the past if i do not take the niacin prior to O.BTW I am 20 years or more younger than you .Welcome to the forum, i hope you learn more about our initiatives and join us!
"Cabergoline is another drug that works the same way as bromocriptine; like bromocriptine, cabergoline is used to treat Parkinson's disease and pituitary disease. It, too, blocks prolactin and enhances dopamine, and it has fewer nasty side effects. One interesting side effect reported in both men and women being treated for things like Parkinson's is multiple orgasms. Which is a hell of a side effect, if you ask me."
Here is an informative and funny article RE: prolactin and one man's quest for multiple orgasms. What's also interesting is that he discusses drugs developed to treat Parkinson's disease that inhibit prolactin and boost dopamine:http://open.salon.com/blog/franklinveaux/2009/03/10/biochemistry_sex_and_hey_multiple_orgasmsQuote"Cabergoline is another drug that works the same way as bromocriptine; like bromocriptine, cabergoline is used to treat Parkinson's disease and pituitary disease. It, too, blocks prolactin and enhances dopamine, and it has fewer nasty side effects. One interesting side effect reported in both men and women being treated for things like Parkinson's is multiple orgasms. Which is a hell of a side effect, if you ask me."I've heard about interesting benefits after taking anti-Parkinson's meds, I wonder if we might have our own?tantalus - I'm sorry you've been ignored, I have my own suicide-inducing problems. But I want you to know, if you have POIS, you are in my family
Tantalus i have 3 questions:1. Since when do you have POIS? Since puberty?2. Did you react to yours partners semen or just your own? Did you get POIS from contact with other males semen?3. What were your side effects during desensitization?
Looks promising. I'm not sure I'd have any success in getting prescribed Cabergoline but if you can find a doctor who'll prescribe it then let us know how you get on.
Quote from: kurtosis on 28/06/2012 20:42:21Looks promising. I'm not sure I'd have any success in getting prescribed Cabergoline but if you can find a doctor who'll prescribe it then let us know how you get on. I've been seeing an open-minded endocrinologist for metabolic syndrome that I developed while taking antipsychotics, he has prescribed me testosterone gel before on speculation it might help my PIOS. He's one of the few docs who has given me the benefit of the doubt. I have a well documented medical history, and it might make him feel secure enough to go with the cabergoline. I will get an appointment soon!