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Another thing, with niacin... do you "O" during the flush? after the flush? How long after the flush? Before the flush?Thanks. Sorry, just beat up with POIS right now.Anybody get night sweats with POIS?
I really want to try this new concoction as I was thinking about just veering off the side of the road into a tree to end this misery. But I had to reassure to myself that my pois worst stage is very short.
Thanks a lot prancer, you are a lot of help.The vitamin concoction. Glad it is working for some people. I don't know if I would say that we have a vitamin deficiency, there's just no way that a normal person would need this amount of vitamins just to have an orgasm without POIS. Maybe it is masking the bodies reaction to it? Maybe we have something in us taking away our nutrients (a parasite) needed to have a successful orgasm?I've also thought of my pois just being a post orgasmic migraine, has anybody ever tried Indometacin?
Quote from: GoingCrazy on 28/07/2012 06:30:49Thanks a lot prancer, you are a lot of help.The vitamin concoction. Glad it is working for some people. I don't know if I would say that we have a vitamin deficiency, there's just no way that a normal person would need this amount of vitamins just to have an orgasm without POIS. Maybe it is masking the bodies reaction to it? Maybe we have something in us taking away our nutrients (a parasite) needed to have a successful orgasm?I've also thought of my pois just being a post orgasmic migraine, has anybody ever tried Indometacin?Parasite, auto-immune, genetic problem impeding or preventing some enzymatic reactions, bacterial infection in the gut... all possibilities. I know I have gut problems revealed in a colonoscopy but a few rounds of antibiotics don't seem to have fixed them. I'm not suggesting that POIS sufferers just need lots of vitamins for no reason but it's going to be very difficult to find out what the actual reason is without a coordinated research programme (which we can't discuss on NSF as it requires funds to be raised). However, to suggest that something is masking POIS is not accurate. We simply do not know what's causing POIS and with this supplement regime my biggest concern is trying to prevent neurological damage from long term POIS. Even if our brain cells are not being attacked by the illness, if its affecting our neurotransmitters such that we can't think then our brain development (and learning of course) is being affected. This is a form of cumulative brain damage where you move farther and farther away from the potential you had without POIS. While we're waiting to figure out what the cause is, I want to be functional. So it's about managing a condition. I never claimed a "cure".
Kurtosis, something is telling me that the Huperzine A is doing it for you. I'm going to buy some today and try just that, and I will let you know how it affects me. (I'm too lazy to go out and get all the supplements listed :/ )
Hi guys, I have been suffering from the symptoms of POIS for my entire adult life (roughly 11 years). Symptoms include brain fog, difficulty maintaining erections, depression, fatigue, anxiety, swelling of eyes, paleness, premature ejaculation, lack of motivation...the list goes on. I seem to get POIS when I get aroused...the symptoms are significantly worse after ejaculation than before, but if I masturbate or have sex without ejaculation or orgasm I still have the symptoms to a lesser degree. I have a few questions for you guys...I am going to see my allergist this upcoming Friday and I am supposed to provide a "specimen" sample of my semen for skin ***** testing. So here are my questions:1). How long before the skin ***** testing should I wait to provide the sample? The doctor said the morning of the appointment is fine (appt is at 10:00 a.m.). I know that sperm dies rather quickly after leaving the male body...will this affect the results of the test if I wait several hours?2). If I do have a reaction to my own semen, will I have to provide a sample every time before I am giving the hyposensitization therapy? Or will they freeze the specimen and use it until they run out?3). It seems like talk about treatment with autlogous semen has died down recently, is it still a viable treatment procedure?4). What is the Kurtosis protocol I keep hearing about? I can't find any exact listing of what it entails as far as vitamins and procedure.5). Are there any new procedures that have had success?I feel like the issue is definitely based in the hypothalamus/pituitary. My theory is that I become aroused and my pre-ejaculate flows through my seminal "plumbing" and interacts with T-lymphocytes in any small gaps in the plumbing. If I ejaculate the amount of fluid interacting with the lymphocytes is increased causing a more severe reaction. The T-lymphocytes reaction then triggers the release of histamine. The histamine causes cortisol to be released to suppress it. A prolonged allergic reaction will create a prolonged cortisol release, interfering with hormones and the pituitary. Also, elevated levels of histamine will interact with the hypothalamus in a negative way, causing neurotransmitters and their release to become imbalanced and possibly even decreasing them.My symptoms are very similar to dopamine deficiency, which I think might play a key role in POIS.Anyways, I would appreciate any feedback and I hope you guys are doing well.Thanks,Chris
Hi guys, I have been suffering from the symptoms of POIS for my entire adult life (roughly 11 years). Symptoms include brain fog, difficulty maintaining erections, depression, fatigue, anxiety, swelling of eyes, paleness, premature ejaculation, lack of motivation...the list goes on. I seem to get POIS when I get aroused...the symptoms are significantly worse after ejaculation than before, but if I masturbate or have sex without ejaculation or orgasm I still have the symptoms to a lesser degree. I have a few questions for you guys...I am going to see my allergist this upcoming Friday and I am supposed to provide a "specimen" sample of my semen for skin ***** testing. So here are my questions:1). How long before the skin ***** testing should I wait to provide the sample? The doctor said the morning of the appointment is fine (appt is at 10:00 a.m.). I know that sperm dies rather quickly after leaving the male body...will this affect the results of the test if I wait several hours?2). If I do have a reaction to my own semen, will I have to provide a sample every time before I am giving the hyposensitization therapy? Or will they freeze the specimen and use it until they run out?4). What is the Kurtosis protocol I keep hearing about? I can't find any exact listing of what it entails as far as vitamins and procedure.Thanks,Chris
I shared it with my parents back then but they were largely skeptical and even to this day they think it is all in my head and accuse me of being a hypochondriac.
This does not agree with Waldinger. Secondly, there was no control group in his work, he explicitly mentions this in his paper:Put it this way, what would a skin-test show on a normal person with no POIS symptoms? It would not surprise me if they too had a reaction, afterall, semen is not meant to be injected directly into the bloodstream. Moreover, he concludes that it is a semen allergy because men to stopped before ejaculating did not experience the symptoms. For me personally, ejaculation coincides with orgasm. So why could it not in fact be the orgasm that is causing POIS and not the ejaculation?
I scored the highest mark in A-level chemistry in the end, I was also given the sixth form prize for mathematics and performance in A-levels. I recently got a masters in physics and was awarded the departmental prize for performance in examinations. Now I have a fellowship to do a PhD in the US. As I gave up on a regular life and relationship, my mind is my most treasured asset. Recently a dangerous idea has began to grow in my mind, that these POIS symptoms might cause damage and that it is not 100% reversible after 7 days (again, symptoms peak in 2 days). I cannot seem to shake this idea and it is really troubling me, as I don't feel as sharp as I used to be...
MSLQuote from: msl on 21/07/2012 14:29:27I shared it with my parents back then but they were largely skeptical and even to this day they think it is all in my head and accuse me of being a hypochondriac.Omg, same exact thing happens to me and it's rediculous. Just because something isn't posted in a medical paper doesn't mean it isn't real. This is probably the thing that really ticks me off about POIS. But thing is that if I didn't have POIS, I wouldn't believe it either. It really takes having it to believe it.Quote from: msl on 21/07/2012 14:29:27This does not agree with Waldinger. Secondly, there was no control group in his work, he explicitly mentions this in his paper:Put it this way, what would a skin-test show on a normal person with no POIS symptoms? It would not surprise me if they too had a reaction, afterall, semen is not meant to be injected directly into the bloodstream. Moreover, he concludes that it is a semen allergy because men to stopped before ejaculating did not experience the symptoms. For me personally, ejaculation coincides with orgasm. So why could it not in fact be the orgasm that is causing POIS and not the ejaculation? This is also rediculous... you think a professional would have a control group in his study. This was also discussed by us right as soon as Waldinger came out with his paper. I also think that too and still believe that it is the orgasm that is causing the allergic reaction, not the semen, as there are too many things being released upon orgasm that can contribute to the POIS feeling, and just because 10 people with POIS react to sperm being put into their bloodstream doesn't mean that is is the sperm causing the feeling.Quote from: msl on 21/07/2012 14:29:27I scored the highest mark in A-level chemistry in the end, I was also given the sixth form prize for mathematics and performance in A-levels. I recently got a masters in physics and was awarded the departmental prize for performance in examinations. Now I have a fellowship to do a PhD in the US. As I gave up on a regular life and relationship, my mind is my most treasured asset. Recently a dangerous idea has began to grow in my mind, that these POIS symptoms might cause damage and that it is not 100% reversible after 7 days (again, symptoms peak in 2 days). I cannot seem to shake this idea and it is really troubling me, as I don't feel as sharp as I used to be...That's great that you are making progress while having POIS. It is very motivating to me as I am also at the most important part of my life which is college. I think it's funny how I can tell that you are a highly driven person just from having avoided orgasms and only having NE's. Many people are in that same boat. I feel too much motivation while not having an orgasm, but it's driven me to a point where I am psychologically inclined to be the best that I can be, almost to a spiritual level, knowing that I am doing the "right" thing supposedly. But sex should be a part of life and nothing to worry about. POIS is what we really need to figure out, and once we do, we can all enjoy life to the fullest and have relationships whether currently we are in them or not.
I don't agree that most people w/o POIS symptoms would have a reaction to their own semen...plenty of women are the recipients of semen on their skin and a majority of them do not have any kind of reaction.I do agree with you that the orgasm appears to be the main culprit...there are so many variables to contend with as far as orgasm is concerned that it's hard to tell what the culprit is...I'm leaning towards thinking it is a dopamine deficiency because many of the POIS symptoms mirror low dopamine.
Kurtosis, have you had any side effects from taking Huperzine A. I have tried other nootropics like Vinpocetine and others, but only ever ate one pill out of the bottle because of side effects.