Naked Science Forum

Life Sciences => Plant Sciences, Zoology & Evolution => Topic started by: neilep on 17/02/2012 13:30:18

Title: Do Non Human Species Have Down Syndrome ?
Post by: neilep on 17/02/2012 13:30:18

Ever seen a Down Syndrome Ape ?..Cat ?...Fish ?...Giraffe ?


whajafink ?

Title: Re: Do Non Human Species Have Down Syndrome ?
Post by: Nizzle on 17/02/2012 14:47:15

I'm fairly sure the genetic basis of the Down Syndrome can also occur in non-human species, but I'm not sure if the symptoms would manifest in the same way...

Title: Re: Do Non Human Species Have Down Syndrome ?
Post by: Lmnre on 10/03/2012 21:11:25

"Trisomic Ts65Dn mice show direct parallels with many phenotypes of Down syndrome (DS), including effects on the structure of cerebellum and hippocampus."

source: Trisomy for the Down syndrome ‘critical region’ is necessary but not sufficient for brain phenotypes of trisomic mice (http://hmg.oxfordjournals.org/content/16/7/774.full)

Title: Re: Do Non Human Species Have Down Syndrome ?
Post by: neilep on 11/03/2012 17:22:22

Quote from: Nizzle on 17/02/2012 14:47:15

I'm fairly sure the genetic basis of the Down Syndrome can also occur in non-human species, but I'm not sure if the symptoms would manifest in the same way...

Thanks Nizzle for your kind response here. Sorry I was slow to acknowledge it. It did not show up as a new post for me...must still be a few gremlins in the system !

Title: Re: Do Non Human Species Have Down Syndrome ?
Post by: neilep on 11/03/2012 17:23:51

Quote from: Lmnre on 10/03/2012 21:11:25

"Trisomic Ts65Dn mice show direct parallels with many phenotypes of Down syndrome (DS), including effects on the structure of cerebellum and hippocampus."

source: Trisomy for the Down syndrome ‘critical region’ is necessary but not sufficient for brain phenotypes of trisomic mice (http://hmg.oxfordjournals.org/content/16/7/774.full)

Thank ewe Lmnre. I appreciate the info anf the link.