[h3]Obesity and precision work[/h3]
For some time I was wondering about aspects of one's state of mind, and the effect on weight gain; in particular, I find that when I am concentrating intently on a problem, I tend to slow down my breathing rate, and when I tend to do lot of such problem solving, I tend to gain weight more. It occurred to me that as I slow down my breathing rate, it must slow down the rate at which I can metabolise fuel, and that this might have as significant an effect as the rate at which I consume food (when one controls the performance of a car engine (at least in old fashioned corroborated engines), one does not actually directly control the fuel intake, but one tends to control the air intake, and the fuel burn then adjusts accordingly – and the same might be happening to the human body).
One of the things that occurred to me is that sportsmen who do high precision sports will sometimes abuse beta blocker in order to slow down their metabolism and steady themselves, in exactly the way that I am naturally slowing down my respiration when doing precision (whether mental or physical precision) work.
http://www.eirpharm.com/healthtips.php?g_id=9&g_name=Sports%20Medicine&id=123
Beta Blockers can be used in precision sports to steady nervous twitches improve accuracy and could potentially be abused in sports such as Gymnastics, Motorcycling, Archery and Shooting They tend to be used at the same levels as for therapeutic use associated with their use for hypertension, some cardiac arrhythmias, or migraine. Side effects of beta-blockers when used in healthy individuals may include cardiac problems including slow heart rate and low heart rate, dizziness and impotence.
It also occurred to me to see if there was any information on beta-blockers and weight gain, and voil :
http://jcp.sagepub.com/cgi/content/abstract/29/3/212?ck=nck
[h2]Obesity and beta-blockers: influence of body fat on their kinetics and cardiovascular effects [/h2]
[h5]F Galletti, ML Fasano, LA Ferrara, A Groppi, M Montagna, and M Mancini [/h5]
Beta-blockers are among the most widely used antihypertensive drugs. They differ from each other in regard to several factors such as: beta-agonist activity, beta 1-selectivity and solubility. Aim of this work was to evaluate the influence of obesity on the kinetics and the antihypertensive effect of two Beta-blockers with different solubility such as: the water-soluble, atenolol and the liposoluble, metoprolol. The study was carried out according to an open randomized cross-over design. Eight obese hypertensive patients, after a two week washout period, were randomly allocated to a four week treatment. After a two week intermediate washout period, each patient switched to the other treatment for an additional four week period. On the first and the last day of each treatment the subjects were hospitalized to collect blood samples for the assay of the two drugs and to measure cardiovascular parameters. Obesity does not exert any effect on the kinetics of the water-soluble beta-blocker, atenolol, while markedly interferes with that of the liposoluble, without any apparent influence on its anti-hypertensive effect. These findings extend to obese hypertensives the concept that the plasma concentrations of beta-blocking agents are not reliable predictors of their therapeutic effect.
Could the increasing amount of high precision work in the modern workplace have more to do with the increase in obesity than the actual reduction in physical exercise, or excess of food?