Naked Science Forum

Life Sciences => Physiology & Medicine => Topic started by: teach on 18/02/2004 18:56:53

Title: Cloning
Post by: teach on 18/02/2004 18:56:53
Hello, this is Anna Wells, and Beth Wright.  We are doing an international research project on cloning.  We are interested in your thoughts on human cloning; do you think it is ethical, or do you think that there should be a law banning human cloning?
Title: Re: Cloning
Post by: Donnah on 18/02/2004 21:43:44
It's a natural step forward for scientists.  We just need to have clear guidelines.
Title: Re: Cloning
Post by: Quantumcat on 19/02/2004 10:49:29
As long as the laws are set down now to stop the bad side affects of cloning, and clear goals are established so scientists know exactly what their aiming for, then I say go for it.

Am I dead? Am I alive? I'm both!
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Title: Re: Cloning
Post by: MissMontana on 19/02/2004 21:54:27
Playing devils advocate here but isn't there a danger that cloning will become just a nicer name for eugenics?
Title: Re: Cloning
Post by: Exodus on 19/02/2004 22:29:08
quote:
Originally posted by MissMontana

Playing devils advocate here but isn't there a danger that cloning will become just a nicer name for eugenics?



Miss Montana, are you some kind of beauty queen or something... was thinking along the lines of
(https://www.thenakedscientists.com/forum/proxy.php?request=http%3A%2F%2Fwww.mikesnewsquips.freeservers.com%2Fph9%2C28%2C2missuniverse.jpg&hash=5c7f4daa24bb970a9a3e843e2b6426f1)

Or are we looking at...

(https://www.thenakedscientists.com/forum/proxy.php?request=http%3A%2F%2Fwww.thecostumer.com%2Fupload%2Fbeauty_queen.jpg&hash=bc2ec055c11189bd5d3aaf8f1beeb2b0)

[;)][:D]LOL[:)]

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Title: Re: Cloning
Post by: MissMontana on 19/02/2004 22:59:04
PMP

Because of the name or the comment?
Title: Re: Cloning
Post by: Ylide on 19/02/2004 23:03:38
Exodus:  That's just wrong, man.  

As far as human cloning goes, I have mixed feelings.  Genetic diversity  and mutations are the cornerstone of evolution.  If you take away the randomness of gamete formation and eliminate mutations, you're essentially halting the progress of evolution.  To advance as a race (or into a new race) you're then going to need to take it upon yourself to decide which traits are advantageous and which are not.  You then find yourself in a dystopian scenario like in Brave New World or Gattaca.  

However, certain cloning-related technologies such as being able to replicate genetically identical organs for transplant has great potential for use in healthcare.  Cloning as a manner of reproduction opens a can of worms that I don't think we're socially mature enough as a race to handle.  



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Title: Re: Cloning
Post by: Exodus on 19/02/2004 23:05:18
PMP- i dont understand what that means... Nah just the name... its like when you have Miss America competitions you have a Miss Florida or Miss Montana etc... was just playing around. [;)]

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Title: Re: Cloning
Post by: Exodus on 19/02/2004 23:06:32
quote:
Originally posted by cannabinoid

Exodus:  That's just wrong, man.  

As far as human cloning goes, I have mixed feelings.  Genetic diversity  and mutations are the cornerstone of evolution.  If you take away the randomness of gamete formation and eliminate mutations, you're essentially halting the progress of evolution.  To advance as a race (or into a new race) you're then going to need to take it upon yourself to decide which traits are advantageous and which are not.  You then find yourself in a dystopian scenario like in Brave New World or Gattaca.  

However, certain cloning-related technologies such as being able to replicate genetically identical organs for transplant has great potential for use in healthcare.  Cloning as a manner of reproduction opens a can of worms that I don't think we're socially mature enough as a race to handle.  



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Wrong?

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Title: Re: Cloning
Post by: MissMontana on 19/02/2004 23:15:00
Peeing my pants or laughing quite intensely

Montana because my name is Toni, Miss because I'm not a bloke
Title: Re: Cloning
Post by: Exodus on 19/02/2004 23:18:20
quote:
Originally posted by MissMontana

Peeing my pants or laughing quite intensely

Montana because my name is Toni, Miss because I'm not a bloke



phew!! thought i'd done some upsetting there! well its damn good to meet you toni. I have not been on here for a few months due to University work, but its nice to be back!

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Title: Re: Cloning
Post by: MissMontana on 19/02/2004 23:25:39
Nah, no upsetting, they were tears of laughter honest
Title: Re: Cloning
Post by: roberth on 19/02/2004 23:42:14
Anyway Richard, I thought I asked you to keep those pictures of my sisters private.
Title: Re: Cloning
Post by: genegenie on 20/02/2004 02:02:32
I have mixed feelings teach. We are products of our genetic make-up BUT environmental influences also have such a huge impact. As a standard practice, I'm against it, for similar reasons as cannabinoid gave relating to genetic diversity and evolution. However, there may be certain situations....????

Science is organized knowledge. Wisdom is organized life.
Title: Re: Cloning
Post by: bezoar on 20/02/2004 02:12:21
But if we clone, and what with apoptosis, won't the clone die sooner?  And let me open up a real can of worms -- will it have a soul?
Title: Re: Cloning
Post by: genegenie on 20/02/2004 09:53:41
I know that there have been problems with telomere shortening, triggering early apoptosis. I'm not sure if it's been overcome yet. Bezoar, I'm not totally convinced of the presence of a 'soul' (well certainly not in the Christian sense) but assuming we all have a soul, then I'm sure that identical twins (both having an identical genetic makeup) would each possess individual souls. A clone shouldn't be 'soul-less'.

Science is organized knowledge. Wisdom is organized life.
Title: Re: Cloning
Post by: Acrinimiril on 20/02/2004 20:02:12
quote:
Originally posted by bezoar

But if we clone, and what with apoptosis, won't the clone die sooner?  And let me open up a real can of worms -- will it have a soul?



 
I love it when creationists say "Yep. God Created me in 6 days."
 
I love it because I get to quote the ever-quotable Bill Hicks who
was thought to have replied "Yeah, I'd say he rushed you."

Did you know that RNA is only passed along the female side since protozoa such as sperm carry only DNA?  The Egg is a complete, if sterile, cell.  But it carries memory that sperm cannot.
Title: Re: Cloning
Post by: Acrinimiril on 20/02/2004 20:14:07

 
PS.  That was NOT troll bait or a flame.
It just p!$$e$ me off.

Tell me, young Einstein, exactly how many pieces do ten fingers blow into?
Title: Re: Cloning
Post by: bezoar on 20/02/2004 23:20:22
I like the Bill Hicks line.  I can think of a few people I'll use it on soon.  Thanks.

And as far as eggs carrying memory, ya think that's why women have better memories than men?
Title: Re: Cloning
Post by: Ylide on 21/02/2004 02:41:42
My favorite Bill Hicks quote about God:

And on the seventh day, god stepped back and said "There is my creation, perfect in every way... oh, dammit I left pot all over the place. Now they'll think I want them to smoke it... Now I have to create republicans."

I'll be all for cloning once they can replicated my body, keep it in cryostorage until I'm near death's door,then transfer my consciousness into my clone.  That would be freakin' sweet.



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Title: Re: Cloning
Post by: genegenie on 21/02/2004 11:22:42
quote:
Originally posted by bezoar

I like the Bill Hicks line.  I can think of a few people I'll use it on soon.  Thanks.

And as far as eggs carrying memory, ya think that's why women have better memories than men?



I think it's why women are better than men, period. (haha, joke fellas)

Science is organized knowledge. Wisdom is organized life.
Title: Re: Cloning
Post by: tweener on 22/02/2004 03:02:50
I just finished reading a book "The Stone Canal" by MacLeod where the technology was advanced to a point where they could completely copy a persons brain patterns, store them, make complete clones (in a couple of weeks) and transfer the brain patterns into the cloned body.  Or they could make machines that could hold the brain patterns and function just as a person would.  It was an interesting concept, though the overall book was a little flat.

Back to this topic, I feel that cloning is just simply making a copy of the DNA and growing a new body.  It does not imply that the new body will be the same person or not have a soul or any such thing.  The new person is a person in their own right and will NOT be the same as their "parent".  Their environment will be completely different in the whole of their life, so they will be a different person.  Identical twins are clones of one another, and they (usually) share as close to the same environment as is possible.  Yet, they are distinct people.

This leads me to something else I read tonight in another thread (written by Quantumcat) that a person will always make the same choice under the same circumstances.  I don't buy that.  The only way that would hold true is if the brain were in the same state when all external circumstances were the same.  This is not possible.  I think that people will react differently to an ambiguous situation because they will always be in a different "state of mind".  A clone would always have a different state of mind than their twin.

Now, given all that, I'm all for "theraputic" cloning that can help cure disease, provide a person with a transplantable organ etc.  I don't strongly favor reproductive cloning because (as Jay said) there are plenty of people.  However, some couples that cannot naturally conceive children might really benefit (at least psychologically) from a cloned offspring.

As for the evolution argument, I don't buy that.  The human population is so large, and our technology so advanced, that natural selection plays no role in our gene pool.  Evolution only really works to change a species when the species is isolated into very small groups for several generations at a time.  This has not been the case with humans for several thousand years now.

I don't think that we as a society are ready for being able to "design" our offspring.  My worst fear is that everyone would want the same traits and thus we would end up more homogeneous than we already are.  Just like everyone going to WalMart and getting the same one or two choices for any product.

Wow, I guess I got started on that one huh?


----
John
Title: Re: Cloning
Post by: Ylide on 22/02/2004 04:55:22
John, is it really cloning if both parents contribute genetic material to the child?  It's more like artificial insemination meets testtube baby at that point.  Formally, a clone is a genetic duplicate of the parent...a child made via an artificial genetic cross would be genetically distinct.  

To address your other point, your experiences and environment dictate your behvior far more than your genetics do.  You may be genetically predisposed to certain behavior (XYY males, homosexuals, etc) but a good deal of your mental development comes during childhood.  You will develop within the parameters of what your genetics allow for, (a downes syndrome kid isn't going to be doing any higher mathematics) but for a normal person, that's a VERY broad range.  

A normal (i.e. not retarded, not genius) can vary from impulsive, uneducated to refined, wise, and intelligent, to street-smart, fast-talking, and crafty.  It's all in the way you're raised and what things happen to you during impressionable years.  Things like illness, poor parental support, even social ostracization can inhibit mental development of a person during childhood years.  

I also agree with you that natural selection no longer plays a role in our society.  When morons hurt themselves doing things like jump onto 20 foot railings on a skateboard, smoking copious amounts of methamphetamine, or driving drunk and still survive because of the emergency medical support they receive from others, we are DEFINATELY not weeding out the unfit.  In fact, our society is oddly configured in that those who SHOULD be progenators of most of the offspring (the more educated and less violent members of society) are the ones spewing out the fewest kids.  



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Title: Re: Cloning
Post by: tweener on 23/02/2004 04:00:40
Jay,
If you are taking my statement "Identical twins are clones of one another,..." to mean that they are not clones, you're right.  What I meant is that they share identical DNA, just like a clone.  Neither one is really a clone because both parents contributed DNA, but compared with each other they are as close to a clone as we can get right now.

I was kind of rambling.


----
John
Title: Re: Cloning
Post by: Ylide on 23/02/2004 07:11:09
No, I was referring to your statement:

"However, some couples that cannot naturally conceive children might really benefit (at least psychologically) from a cloned offspring."

It's not really cloning if each parent contributes one set of chromosomes.  It's related technology of course, but not really cloning in the formal sense.



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Title: Re: Cloning
Post by: Quantumcat on 23/02/2004 10:44:14
Well, twins aren't clones, because one wasn't made from the other, but they share genetic material like a clone, because both parents gave exactly the same genes to them as the other ... And they already do artificial baby-making now don't they? they take an egg and a sperm and introduce them ...  then in a few weeks implant it in the mother. At least that's what I thought.

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Title: Re: Cloning
Post by: tweener on 23/02/2004 19:34:31
Jay,
In talking about couples benefit from a cloned offspring, I meant that the offspring would be a clone of one of them (or maybe someone else).  They would still have a child to raise, which is presumably what they wanted.  I know that they wouldn't both contribute DNA or it wouldn't be a clone.  Then it would be in-vitro fertilization.  And, if I remember correctly, IVF caused almost as much hoopla when it was new as cloning is causing now.  

I just hope that the conservatives (aka religious fanatics) can't bully their way on this issue.  Someone in some country will press ahead, and I think it would be better to lead the way rather than follow.  But we (the USA) seem to be following more and more lately.

And QC you are absolutely right!


----
John
Title: Re: Cloning
Post by: Ylide on 24/02/2004 07:31:00
Ah, thanks for clarifying, John.  I was misinterpreting what you were saying.  

The Bible-thumpers always manage to muscle their way into any research that involves the creation of human life.  They have the market cornered on divinity and they'll eat their shoes before they'll mankind demonstrate the ability to make life as their God supposedly did.



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Title: Re: Cloning
Post by: tweener on 24/02/2004 19:16:42
I wish they would eat their shoes.  They are usually too busy trying to shove them down someone else's throat.


----
John
Title: Re: Cloning
Post by: chris on 25/02/2004 08:17:35
Definition of "Clone" (from Google online dictionary)

1. A segment of DNA contained within a cloning vector.
2. An organism derived from a founding individual by asexual means that is genetically identical to the founding individual.

Technically speaking I would argue that identical twins are "clones" because a single fertilised embryo - the founding individual - splits to give rise to a second genetically identical individual. Twins therefore fit the definition.

It is worth bearing in mind that the present-day clones that we have been creating are not actually genuine clones. There are subtle differences between these specimens and a pair of twins.

All clones start with an enucleated egg (an egg from which the nucleus has been artificially removed). The reason for doing this is that egg cells contain the necessary machinery (mitochondria) for making energy in the new cells. But more significantly, eggs also contain specially primed cytoplasm (the liquid part of the cell) that can re-activate the developmental programme in DNA that guides embryonic development. This programme is shut off in adult cells and for good reason - because it shares some of the same mechanisms as cancer - rapid and invasive cell growth. We don't yet know the identity of many of these chemical factors that can re-awaken DNA that has been shut-off, which is why we need to rely on eggs to do the job for us.

Now, if the egg you use to make your clone is one of your own then you can expect to produce a genuine clone of yourself. But if, as frequently is the case, the egg you use is not one of your own - then the result will not be a geunine clone - because the mitochondria in each of the clone's cells will be derived from the original egg, and mitochondria contain their own genetic material.

To change the subject completely, you are absolutely right to question the role of DNA in guiding your behaviour and development. Our brains are products of our experiences with the best example being 2 identical twins separated at birth and raised in different countries. One would grow up speaking say French, and the other German or English. This is an example of how 2 genetically identical individuals would behave differently due to different life experiences.

I have covered much of this, and some more belt-and-braces cloning considerations in this article :

http://www.thenakedscientists.com/HTML/articles/article/chrissmithcolumn.htm

Chris


"I never forget a face, but in your case I'll make an exception"
 - Groucho Marx
Title: Re: Cloning
Post by: tweener on 25/02/2004 20:29:37
Chris, it is good to see you posting again!

----
John - The Eternal Pessimist.
Title: Re: Cloning
Post by: bezoar on 26/02/2004 05:21:10
I'll second that!  Missed you Chris.  Good to have you back.
Title: Re: Cloning
Post by: christianchick on 26/03/2004 14:16:24
i think it should be banned only because of the natural desire in man to always want more, and because i want identity theft to stay with my credit card and ss#, not with my entire self

i have been here longer yet you seem to be more advanced...
Title: Re: Cloning
Post by: Quantumcat on 27/03/2004 11:20:07
WHat the heck????

Am I dead? Am I alive? I'm both!
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Title: Re: Cloning
Post by: MayoFlyFarmer on 27/03/2004 19:13:34
its far fetched, but it does make sense

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