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That's fantastic news, congratulations B_Daniel!I wonder if there are 2 Pois (hormonal unbalance and auto-allergy) or 1.Are allergic people more exposed to hypotestosteronemia than others ?http://www.aehf.com/articles/Testosterone.htm Quote 125 male allergy patients were studied 117 (94%) of these patients were diagnosed with Hypotestosteronemia QuoteConclusionThe results demonstrate that testosterone supplementation, when indicated in patients with allergic disorders, provides significant improvement in the patient’s overall health, well-being and energy level. An overwhelming number of male patients who were treated for their allergies in combination with testosterone supplementation, when indicated, reported a marked improvement in their original symptoms.
125 male allergy patients were studied 117 (94%) of these patients were diagnosed with Hypotestosteronemia
ConclusionThe results demonstrate that testosterone supplementation, when indicated in patients with allergic disorders, provides significant improvement in the patient’s overall health, well-being and energy level. An overwhelming number of male patients who were treated for their allergies in combination with testosterone supplementation, when indicated, reported a marked improvement in their original symptoms.
Quote from: kurtosis on 02/03/2012 08:46:42Quote from: observercenter on 01/03/2012 10:50:43Quote from: GoingCrazy on 01/03/2012 06:19:42 Unless someone could tell me why I would feel symptoms of being allergic to semen only in my brain.I bet that a lot of folks here would want to know the answer too. I do not know if this could serve as an answer; but every time when i had an ejaculation in the past i used to feel a "weird feeling" on my head. I felt exactly the same feeling on my head at the moment they were injecting my own semen- dilluted concentration of course- on the skin p- test. That was my 100% confirmation that i am reacting against my semen -(probably when it contacts the blood barrier?).Possibly because histamine is such a "swiss army knife" compound in the body. Have a look at http://en.wikipedia.org/wiki/Histamine"[Histamine is]...involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter". I think this all comes down to the "flight/fight" response and evolutionary biology. I suspect that an allergic reaction post orgasm is the exact wrong time to have it as an orgasm involves so many chemical reactions in the brain, some of them controlled by histamine receptors which regulate neural transmitter release. So instead of a really pleasurable post-O bliss that I'm told other people get, we get this headache, fuzzy feeling and dread. Of all the things you could have an allergic response to, seminal fluid is very unlikely but it doesn't seem to lead to infertility. So even something as seemingly ridiculous (and it does seem nuts) as a semen allergy could be passed on from generation to generation without it being properly diagnosed or cured. I don't believe we're the first people with POIS, just the first who have labelled it and are trying to analyse it in medical terms. There's also a strong relation between histamines, niacin and neurotransmitters like dopamine and serotonin. These last two of course act over the brain.The fabrication of histamines consume materials that dopamine and serotonin also require. Since a heavy load is demanded (for some reason heavier in POIS cases, maybe autoimmune reasons maybe not) the "building materials" become depleted and we remain short of dopamine etc until we can finally recuperate them. (5 or so days later).
Quote from: observercenter on 01/03/2012 10:50:43Quote from: GoingCrazy on 01/03/2012 06:19:42 Unless someone could tell me why I would feel symptoms of being allergic to semen only in my brain.I bet that a lot of folks here would want to know the answer too. I do not know if this could serve as an answer; but every time when i had an ejaculation in the past i used to feel a "weird feeling" on my head. I felt exactly the same feeling on my head at the moment they were injecting my own semen- dilluted concentration of course- on the skin p- test. That was my 100% confirmation that i am reacting against my semen -(probably when it contacts the blood barrier?).Possibly because histamine is such a "swiss army knife" compound in the body. Have a look at http://en.wikipedia.org/wiki/Histamine"[Histamine is]...involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter". I think this all comes down to the "flight/fight" response and evolutionary biology. I suspect that an allergic reaction post orgasm is the exact wrong time to have it as an orgasm involves so many chemical reactions in the brain, some of them controlled by histamine receptors which regulate neural transmitter release. So instead of a really pleasurable post-O bliss that I'm told other people get, we get this headache, fuzzy feeling and dread. Of all the things you could have an allergic response to, seminal fluid is very unlikely but it doesn't seem to lead to infertility. So even something as seemingly ridiculous (and it does seem nuts) as a semen allergy could be passed on from generation to generation without it being properly diagnosed or cured. I don't believe we're the first people with POIS, just the first who have labelled it and are trying to analyse it in medical terms.
Quote from: GoingCrazy on 01/03/2012 06:19:42 Unless someone could tell me why I would feel symptoms of being allergic to semen only in my brain.I bet that a lot of folks here would want to know the answer too. I do not know if this could serve as an answer; but every time when i had an ejaculation in the past i used to feel a "weird feeling" on my head. I felt exactly the same feeling on my head at the moment they were injecting my own semen- dilluted concentration of course- on the skin p- test. That was my 100% confirmation that i am reacting against my semen -(probably when it contacts the blood barrier?).
Unless someone could tell me why I would feel symptoms of being allergic to semen only in my brain.
B_Daniel - It's really good to read of another person on here who is over the moon with success from a treatment/therapy.I have a couple of questions for you. A. You said 'Testosterone in pill form - tells your body to produce more T'. I think you are mistaken here. Adding in external T does not stimulate your gonads to produce more. What were you on here...Andriol?B. What mg dosage are you taking currently in gel form per week?C. What levels are showing on your path tests..are you in the middle or in the top 1/3 for your age group?
Could you post your testosterone Resultats please? Thank you !
Check this out. It's about the relationship between testosterone and histamine.http://ajplegacy.physiology.org/content/201/4/740.abstract"Administration of testosterone propionate suppressed the output of free histamine... which showed the effect only after repeated administration of this hormone""When repeatedly treated with testosterone, female rats eliminated exogenous histamine more like males."- This could be why only the patches of T work for demo and you, it is a repeated administration.
Great stuff Daniel! I'm very happy for you! Testosterone works, very effectively for me, but use with caution as it will exacerbate any underlying Psychiatric issues, my anxieties and depression have heightened, and I used an Aromatase inhibitor to counteract the dumping of excess estrogen.
A. I was on the pill Clomid. This does regulated your body's internal T production. I'm now on Axiron, which is a foreign T and has my body producing less of its own.B. I'm taking 30mg per day.C. This is unclear as I've been getting on and off the T. My T levels were low-normal to normal going in.
Have you ever tried daily patches? It seems that you could achieve better and more stable control over the levels that way. Our two cases of "success" seem to have better success with a "daily method". As you see with B_Daniels report, that the daily method also allows him to tone down a day or two if he feels he's getting to horny. And/or you can boost it a little just after sex, or when you feel it's necessary.
Quote from: GoingCrazy on 02/03/2012 21:57:28Check this out. It's about the relationship between testosterone and histamine.http://ajplegacy.physiology.org/content/201/4/740.abstract"Administration of testosterone propionate suppressed the output of free histamine... which showed the effect only after repeated administration of this hormone""When repeatedly treated with testosterone, female rats eliminated exogenous histamine more like males."- This could be why only the patches of T work for demo and you, it is a repeated administration.I think this is very interesting especially since myself and others have had significant success from taking antihistamines.
- My Testosterone...levels have not been tested so far, would this make sense?
I see there are a few posts lately talking about histamine. I can't remember ever getting an abnormal reading for this on any on my past path tests. what I did score high on though was homocysteine and Immunoglobulin G (elevated levels are associated with allergy and I was in top 0.2% of population). Anti-histamines like Zantec have helped me a bit with brain fog.
You men need some solid, scientific research.Do what you can to alleviate the symptoms in the short term -- but go for that research grant!!!