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Physiology & Medicine / Re: Aspirin and immunosuppression
« on: 16/05/2004 04:09:25 »
ok long shot, i'm probably wrong;
amongst other prostaglandins that are produced though the cyclo oxygenase pathway, are the prostaglandins PGE2 and PGI2. They are vasodilators. Their effect may facilitate the action of other substances like the C5a complement element and LTB4, thus making LTB4 easier to attract more neutrophils.
However, it's not as if you've been taking glucocorticosteroids! I would say asprin has a negligable effect on the immune system.
amongst other prostaglandins that are produced though the cyclo oxygenase pathway, are the prostaglandins PGE2 and PGI2. They are vasodilators. Their effect may facilitate the action of other substances like the C5a complement element and LTB4, thus making LTB4 easier to attract more neutrophils.
However, it's not as if you've been taking glucocorticosteroids! I would say asprin has a negligable effect on the immune system.