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General Science / Re: Does hypoxia trigger neurogenesis?
« on: 28/02/2015 19:35:32 »
This is a very interesting study about how three half-hour bouts of exercise induced hypoxia in obese males led to a significant increase in carbohydrate oxidation across 7.5 hours as compared to subjects who were not in the hypoxic condition. Perhaps this is what I thought I felt after my little 20 minute bouts of exercised induced hypoxia -- the apparent deep tiredness that I speculated I felt more after hours of back-packing. Hmm...
The following article is at: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108629
"Impact of Exercise and Moderate Hypoxia on Glycemic Regulation and Substrate Oxidation Pattern
Takuma Morishima, Ayaka Mori, Hiroto Sasaki, Kazushige Goto
Published: October 16, 2014DOI: 10.1371/journal.pone.0108629"
"We understand that some limitations should be carefully considered for interpretation of the present study. First, subjects in the present study were overweight men, but they did not have any metabolic disorder, which may affect the present results. Further studies using severely obese people or people with type 2 diabetes are necessary to extend our understanding. Second, substrate levels in blood do not correspond correctly to substrate utilization because substrate levels such as glucose, lactate or FFA are influenced by the rates of appearance and disappearance. This will partly explain for lack of attenuations of glucose and insulin responses in hypoxia, in despite of augmented carbohydrate oxidation.
"Conclusion
"Neither rest alone nor rest and exercise under moderately hypoxic conditions attenuated postprandial glucose responses. Additionally, rest alone under moderately hypoxic condition did not affect the substrate oxidation pattern markedly. However, carbohydrate oxidation was enhanced significantly over 7.5 h when three bouts of submaximal exercise were incorporated under moderately hypoxic conditions."
This is an interesting factor, I think -- exercise-induced hypoxia. Might be particularly useful for those with diabetes, by clearing the system of carbohydrate, as well as, perhaps, helping one be resistant to stroke, etc.
Yours,
Caleb
The following article is at: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108629
"Impact of Exercise and Moderate Hypoxia on Glycemic Regulation and Substrate Oxidation Pattern
Takuma Morishima, Ayaka Mori, Hiroto Sasaki, Kazushige Goto
Published: October 16, 2014DOI: 10.1371/journal.pone.0108629"
"We understand that some limitations should be carefully considered for interpretation of the present study. First, subjects in the present study were overweight men, but they did not have any metabolic disorder, which may affect the present results. Further studies using severely obese people or people with type 2 diabetes are necessary to extend our understanding. Second, substrate levels in blood do not correspond correctly to substrate utilization because substrate levels such as glucose, lactate or FFA are influenced by the rates of appearance and disappearance. This will partly explain for lack of attenuations of glucose and insulin responses in hypoxia, in despite of augmented carbohydrate oxidation.
"Conclusion
"Neither rest alone nor rest and exercise under moderately hypoxic conditions attenuated postprandial glucose responses. Additionally, rest alone under moderately hypoxic condition did not affect the substrate oxidation pattern markedly. However, carbohydrate oxidation was enhanced significantly over 7.5 h when three bouts of submaximal exercise were incorporated under moderately hypoxic conditions."
This is an interesting factor, I think -- exercise-induced hypoxia. Might be particularly useful for those with diabetes, by clearing the system of carbohydrate, as well as, perhaps, helping one be resistant to stroke, etc.
Yours,
Caleb