Naked Science Forum
Life Sciences => Cells, Microbes & Viruses => Topic started by: thedoc on 09/12/2014 15:30:01
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Jonathan Michael Acha asked the Naked Scientists:
Hi, I would like to ask, if Natural Killer cells attack cells that have insufficient MHC class I molecules in their surface, then why don't they attack Red Blood Cells which are non-nucleated and have no MHC I molecules?
What do you think?
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by its reciptors they know the body reciptors so they attack any unfamilliar reciptor
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why don't (Natural Killer cells) attack Red Blood Cells which are non-nucleated and have no MHC I molecules?
Because they all attended Thymus Immune Cell High School, where they only graduate if they don't attack normal cell types found in the body.
See: https://en.wikipedia.org/wiki/T_cell#Positive_selection