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I often wondered whether Demografx and I were approaching the same solution from different directions. The articles below hint strongly that Viagra can have the effect of increasing oxytocin production during orgasm:http://www.reuniting.info/science/viagra_and_oxytocinhttp://www.news-medical.net/?id=29102Now I know Viagra and Levitra aren't identical, but their effects are sufficiently alike that you have to wonder whether Levitra might not also aid in increasing oxytocin production?I initially started taking Fenugreek to try to boost my oxytocin levels - could we both be achieving the same effect using different methods?
Have been traveling, so catching up now on lots of interesting posts. Mostly wanted to react to John23's comments. My voice gets deeper too after O (for a day or two). Also, the list of symptoms related to hypogonadism comes very close to my key symptoms, except that I definitely do not suffer from "small gonads". All this points to a very puzzling dynamics in the link between testosterone and POIS.
Yes, hurray, I've been thinking that way for some time, even posted briefly about Levitra stimulating oxytocin. So I really appreciate hearing that from you as well.Viagra might be the same. I'm just afraid to try it, because I tried Cialis and it was a disaster. But Cialis I think works differently to produce that very-long lasting effect (36 hours?).But in my case, I think testosterone - in combination with Levitra - plays a critical part of my POIS cure. When testosterone was out of my system, Levitra worked very poorly alone. Sometimes, some drugs simply stop working, but my intuiition says it was the combination that was critical.
Quote from: demografx on 24/02/2009 22:07:18Yes, hurray, I've been thinking that way for some time, even posted briefly about Levitra stimulating oxytocin. So I really appreciate hearing that from you as well.Viagra might be the same. I'm just afraid to try it, because I tried Cialis and it was a disaster. But Cialis I think works differently to produce that very-long lasting effect (36 hours?).But in my case, I think testosterone - in combination with Levitra - plays a critical part of my POIS cure. When testosterone was out of my system, Levitra worked very poorly alone. Sometimes, some drugs simply stop working, but my intuiition says it was the combination that was critical.I think all 3 drugs are supposed to be PDE5 inhibitors, but only Cialis has the long-lasting effects - so it would seem likely that V+L were the most closely linked.Your success with testosterone and Levitra sounds like a real breakthough! I wonder whether this approach would work with some of the other POIS sufferers on the board (strict medical supervision permitting)?
Getting the right medical expertise seems to be the key to nailing POIS - hope it continues to work for you Demo
One other thing - when I am suffering from POIS, it physically feels as if my frontal lobe of my brain has almost closed down, and what conscious thoughts I am having are coming from the sides of my brain, which apparently are the temporal lobes.Wikipedia says:Damage to the frontal lobes can lead to a variety of results:Mental flexibility and spontaneity are impaired, but IQ is not reduced. Talking may increase or decrease dramatically. Perceptions regarding risk taking and rule abiding are impaired. Socialization can diminish or increase. Orbital frontal lobe damage can result in peculiar sexual habits. Dorsolateral frontal lobe damage reduces sexual interest. Creativity is diminished as well as problem solving skills. Distraction occurs more frequentlySome of these certainly ring true from my experience of POIS. If I had to guess which area of the brain was most affected by POIS, I would definitely pick the frontal lobes. Plus, the frontal lobes is where most of the dopamine lives, which is possibly one of the things you are interested in measuring.
Regarding my Endo - she shut me down yesterday and said that she will no longer test for POIS. I could feel this coming so no hard blow there. Instead I have an appt this afternoon with another doctor. Go go persistance.
So I bring the Netherland study and newpaper article, and give them to the [new] doctor. As he's reviewing the literature I'm rambling off all the symptoms, durations, and my speculations of causes - I suggest a 24hr urine cortisol test. When he's done reading, he stares at the ground for like a minute (complete siliance), then he looks at the ceiling same amount of time, then all he say is 'hmmm' - I kid you not.After I feel a bit awkward and question why I'm there, he says 'well I've never heard of this, and you should see an endocrinologist, and if I give one test that will never end, and it might be psychological, and these doctors from the studies aren't from the US'. So I interrupted him and began talking so much he couldn't get another word in...it was quite rude. BUT it worked! I got the paper work for the test!Bold and italicized/underlined emphasis mine - demo
That [cognitive symptoms] sounds a lot like me, I know I am smart, it's just that I can't perform that well. I think when I get these headaches my frontal lobe is trying to come back from its current state. This explains ADD