1

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 10/08/2012 02:45:00 »

Lastly, I also have experienced this cloudy urine. For a long time I have suspected that it is semen. Some places you read will tell you that it is phosphates and I think a way to test this is to add a potent acid to a beaker of the cloudy urine (like a strong vinegar or something) and it should go clear if it is phosphates. Like amijgoro I also have this "hair trigger penis". It makes riding the bus, cycling and some trousers very very uncomfortable - I hate it, it makes me feel very lightly POISy. So even when I haven't had an orgasm for a very long period of time, I still have this to contend with which gives me light POIS symptoms, so pure blissful mental clarity is something I don't often have I'm not sure if this is different from persistent sexual arousal disorder, I think it is because it is not that I have an erection all the time. Makes me suicidal sometimes! ^^ Nobody would understand though except for the people on this forum.

2

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 10/08/2012 02:24:50 »

Here's another back story. I was out in Coventry on the street and it got quite late. I was on the way back to the bus stop when two guys started giving me some trouble. A fight broke out and I fought them for a bit but being two against one they beat me down quite a bit until luckily some other people ran over and chased them off. I wasn't too bad, I had no blood or anything but I was quite dazed. The people called for an ambulance and when the paramedics arrived they looked at my pupils and kept asking me if I had "taken something". I repeatedly said no (not even alcohol) and they were very sceptical. So keywords are

sympathetic nervous system
eye dilation
fight-or-flight
dopamine

but here's the thing, dilated pupils from what I have read are caused by an EXCESS of dopamine. Isn't the general concensus that POIS is related to a lack of dopamine? Your thoughts please ^^

3

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 10/08/2012 02:05:04 »

Does anybody else get really large pupils/dilated iris during POIS-time? This is something that I have noticed. The reason I noticed is that I have eye-floaters (trivial problems in themselves, they are the shadow of clumps in the vitreous gel of the eye) and they became more obvious during POIS-time. Now everytime I look in the mirror I seem to have really dilated eyes. Why exactly this occurs I think is a really interesting question because I think it has something to do with the sympathetic nervous system.

4

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 21/07/2012 14:29:27 »

Hey everyone,

I'd like to introduce myself. I have actually been on and off visiting and reading the posts on this forum for many years. Well, I found it a while back but then stopped visiting for a period. I first noticed POIS when I was about 15. At first I would be perhaps at most 2 days ill afterward... but then over time this grew to the present 7 days. My complaints are exclusively cognitive. I feel very very slow mentally with difficulty concentrating.... well actually no... I can concentrate but everything requires much much more effort mentally than usual and sometimes I am unable to accomplish what would normally be trivial. Recalling information becomes hard. I have difficulty speaking and recalling words. This was particularly frustrating when I had a nocturnal emission before my german oral exams at school. My behaviour becomes completely different. I am admittedly a bastard to everyone around me. I first shared it with my parents when I become extremely bitter/angry/depressed when I had a nocturnal emission very shortly before a large chemistry A-level exam. As you have probably guessed, I do not masturbate and have no partner, hence why I have these nocturnal emissions from time to time. I shared it with my parents back then but they were largely skeptical and even to this day they think it is all in my head and accuse me of being a hypochondriac. I went to the Doctor and he gave me Prozac primarily because of the side-effect which decreases libido, for the purpose that this would lower the frequency of NEs. I took that for a while and then stopped. I revisited the doctor then at university to try and push this all further and was met with scepticism and disbelief. I guess I visited two more doctors at this stage. I had my first year exams at university and I had more NEs due to the stress. I complained to my parents but all they said was "Well its just the stress" "Its the stress thats doing this...". I visited the mental health counsellor at university and she was the first to take me seriously. She referred me to a genitourinary specialist at the erectile dysfunction place at the hospital who gave me a physical exam and quickly passed me on to another specialist, namely a sexual psychotherapist. He again tried to tell me that this is all in my head. At this point, even I was beginning to question my own judgement and sanity. I figured... maybe I should just lighten up and have sex.. for fun. But obviously this did not work. At this point, I was so fed up and despairing with all of the doctors I had seen (I had visited other GPs in between), so I gave up. I dont engage in any sexual activity whatsoever. I gave up on the hope of a relationship with a girl. I accepted that I would be alone in life. And what is more, I would even be happy in this life, if it were not for these NEs happening still. I went back to prozac and then went off it again. I distinctly remember a very ill week in my 3rd year of university, on the week when my first exams would begin. I worked so hard for these exams and then an NE, I was incensed. I stopped reading this forum at a point because there were really so many different "remedies" that people had come up with that it was becoming a bit ridiculous (i don't mean to offend). It seems everyone was clutching at straws and out of desperation latching on to something which claimed to help. If a medical practitioner saw this and didn't give it any credibility, I would forgive him for that. It seems anything from wheat-grass to herbs to anticonvulsants to antihistamines to hormone injections are helping people. This does not give our condition any credibility, in fact, it makes it lose credibility. That there are so many different remedies suggests that this is a psychological condition, when everyone here knows that it certainly is not! I think that peoples judgement on something helping is biased by their absolute desperation and hope that it will help.  If this is a real objective condition then there is an absolute etiology for these symptoms and hence there must exist a definite mechanism by which a medication would help, they cannot all be working.

I have been in touch with two guys, namely, victor and juan-pablo. They have been very supportive and from them I have learned about Niacin and the recent papers. I am curious about the autoimmune hypothesis proposed by Waldinger. However, I am still sceptical. Firstly, symptoms are supposed to alleviate with desensitization treatment. But I've already been exposing my body to my own semen for years, without it getting better! This does not agree with Waldinger. Secondly, there was no control group in his work, he explicitly mentions this in his paper:

"Although the current study supports our
hypothesis of an immunogenic reactivity against
autologous semen, the current study contains an
important limitation due to the current prelimi-
nary observational design. One of the main ques-
tions that still needs answering is whether clinical
and immunogenic responses post-ejaculation are
different in two intentionally recruited groups,
e.g., individuals with POIS criteria vs. a control
group. In other words, the current study does not
provide data on sensitivity and specificity of skin-
***** testing in POIS. Another intriguing question
is whether hyperreactivity against autologous
semen is confined to POIS or to a common phe-
nomenon in the general population.
"

Put it this way, what would a skin-test show on a normal person with no POIS symptoms? It would not surprise me if they too had a reaction, afterall, semen is not meant to be injected directly into the bloodstream. Moreover, he concludes that it is a semen allergy because men to stopped before ejaculating did not experience the symptoms. For me personally, ejaculation coincides with orgasm. So why could it not in fact be the orgasm that is causing POIS and not the ejaculation?

I am personally worried about the auto-immune hypothesis. Auto-immune responses are always to do with inflammation. I would be very worried if it were the brain that is becoming inflamed and is causing these cognitive defects. I would like to ask if anyone has had an MRI scan WHILST IN POIS to see if there is anything abnormal. In Waldingers papers with the two case studies it says that nothing normal is observed in the MRI, but it does not say whether the patient is in a POIS episode or not.

I scored the highest mark in A-level chemistry in the end, I was also given the sixth form prize for mathematics and performance in A-levels. I recently got a masters in physics and was awarded the departmental prize for performance in examinations. Now I have a fellowship to do a PhD in the US. As I gave up on a regular life and relationship, my mind is my most treasured asset. Recently a dangerous idea has began to grow in my mind, that these POIS symptoms might cause damage and that it is not 100% reversible after 7 days (again, symptoms peak in 2 days). I cannot seem to shake this idea and it is really troubling me, as I don't feel as sharp as I used to be...

5

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 25/01/2009 10:29:19 »

hey londonchap, im in the uk too!! im from bournemouth, but am at warwick university at the moment. I have decided to go see the neurologist/sexual psychotherapist. Knowing the uk tho the appointment probably got cancelled because I want quick enough xD will find out on monday.. guess what, going through POIS =D but only myself to blame would you guys class yourselves as very "sexual beings" ?

Hi rapidgaming--
I'm curious. I've had POIS over 20 yrs and am considerably older. I'm just wondering what a younger person suspects to be the cause. I wish I could go back in time and theorize. Do you have an inkling, or are you like most of us, totally perplexed ? Yes to your last question. I'd love to hear your thinking/intuition, even if you don't know.

Hmm well ok I don't know if i can be of much help but I guess these are the things which I think about. Well I began masturbating during puberty.. which I guess and thought at the time was normal? I think back then I was actually quite stressed out so I perhaps masturbated more than the next guy? Then I started to notice that the next day after masturbating I would feel a bit run down, so i remember thinking to myself that If i wanted to masturbate, if I had done the day before then I would not. After time this run down period began to increase until about a week and the symptoms began to be so bad that I would not masturbate. The symptoms did not warrant the intial pleasure, so i began being abstinent (but this was hardxD) particularly how there is temptation everywhere. At one point i installed an internet filter on my computer because I did not want to be tempted by anything. And for long periods of time I could manage to not even think about it, perhaps 2 months or so. But if I relapsed and did masturbate my thought process is as follows:
-well im gonna be really bad for a week now anyway..
-might as well do it again
So the case is that if i masturbate, i find it very hard to stop repeatedly masturbating after that (i remember reading something similar here by someone). This is of course different to the usual thing which happens with guys, once and then thats completely fine for them because they are "satisfied" and go to sleep. it seems with me im still unsatisfied. So for the longest time i did not masturbate but then because i was getting no sexual release i was getting wet dreams, which gave the same results for the following week. Now we reach where I am now, im weening off the prozac and I thought if i just thought "this is natural dont worry about it, its probably in your head" then it would be ok. like a therapist i spoke to said i might be "hung up" about the issue now and just try to relax. So yesterday i masturbated, and many times after that, and now i feel really bad xD huzzah! Also accompanied by feelings of guilt because although i did not view pornography, i did view the old arousing video on youtube which comes pretty close to it and i am thinking that i am some sort of "pervert" because I do not want to objectify women and I feel bad for doing so because of thoughts of this girl i am close with. But sometimes when you just feel "horny" i wonder whether it is actually possible to reason your way against something :/ I don't think im a bad guy.. I think i began masturbating more as a way to cope with stress, also when im more stressed out then its more likely i have a wet dream. Also if i eat very unhealthily that day i am more likely to have a wet dream. but as previously mentioned i relapsed yesterday. I guess i still view it as something wrong aside from the fact that it gives me negative symptoms. My guess would be that i "burnt up" myself earlier on in life and am suffering from some sort of endocrine/neurological exhaustion or something :/ I remember thinking sometihng is DEFINATELY wrong with us, recently i started thinking if i put it all behind me and just didnt get hung up about it as in "yeah masturbate, its ok" then i wouldnt feel as bad, but i still do so... i don't know

6

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 24/01/2009 22:22:24 »

hey londonchap, im in the uk too!! im from bournemouth, but am at warwick university at the moment. I have decided to go see the neurologist/sexual psychotherapist. Knowing the uk tho the appointment probably got cancelled because I want quick enough xD will find out on monday.. guess what, going through POIS =D but only myself to blame would you guys class yourselves as very "sexual beings" ?

7

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 23/01/2009 16:01:17 »

Hi guys, its been a while. For some reason I don't know where to place POIS anymore :S I have seen numerous doctors, an erectile dysfunction doctor and have been taking prozac for 1 or 2 years now to reduce the frequency of nocturnal emissions. After the erectile dysfunction consultant was unable to help, he referred me to a neurologist and a sexual psychotherapist.. yet the appointment letter has been lying on my desk for weeks now :/ months ago I would have lept at the oppertunity, but now I can't shake the thought "is this all in my head?" What do you guys think?

8

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 06/11/2008 17:03:30 »

"I had come across the following article from Lancet long ago. It is somewhat inversely related to your case. Interestingly, the patient was cured with antiepileptic, carbamazepine 300mg."

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New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 06/11/2008 17:02:39 »

also notworth is:

"Dr. David Rabinowitz advised a full battery of investigations, and raised the possibility of a dissociative state, or a variant of Transient Global Amnesia. Dr. Ganesh Adaikan forwarded an article from the lancet where a woman with similar symptoms was cured with the antiepileptic, carbamazepine. Dr. Broderick also advised ruling out arrhythmias and blood pressure disorders by an ambulatory halter monitor and Blood Pressure cuff, then proceeding with considering dissociative states."

Taken from http://www.issm.info/prod/system/main/index.asp?page=/prod/data/issirlist/digest13.htm

10

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 06/11/2008 16:59:58 »

Sorry guys but im in a bit of a bad mood! have we supposed almost every single cause under the sun by now? Testosterone, endocrine stuff, intestinal stuff? candida, blood pressure, neurotransmitter depletion, dopamine all this sorta stuff. I went to my gp the other day, she referred me to an erectile dysfunction clinic (the waiting period is around 11 weeks). I dont know where thats gonna go but i dont feel very enthusiastic. Howeverm My counsellor said that she had heard of cases where orgasm had induced an epileptic attack or fit. READ THIS http://en.wikipedia.org/wiki/Postictal_state
Do the words written here jump out of the page to you, like they did me?

“poor attention and concentration, poor short term memory, decreased verbal and interactive skills, and a variety of cognitive defects specific to individuals.”

Sound familiar? Also notice it mentioned that you may not be aware you have had a seizure. On further research i am under the impression that epilepsy is a very complex condition and that you do not have to have a "fit" (as what would normally assosciate with epilepsy) to have a seizure. the Neurotransmitter depletion suggestion as the cause for a post ictal state makes perfect sense to me. What do you all think?

11

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 29/10/2008 17:38:26 »

Hi people, I went along to my university health coordinator and she was very sympathetic and supportive with our cause =) She said she is going to contact some neurologists in oxford/at oxford (cant remember which:P) she had a special name for the institute, but i cant remember. She said hopefully because it is coming from her they will have the courtesy to reply shedding what knowledge they have. Also she suggested that I try and find a neurologist, because she definately thinks its something physiological rathern than psychological, and run tests to see what actual changes are in the brain. This would mean masturbating for the process of the test. Has anybody done anything like this before? Im will to give it a go i think, but admittadly we were both in agreement that finding a neurologist will be difficult, but she said it can and should be done. She wondered if it might be a form of epilepsy?

12

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 13/10/2008 10:42:05 »

Chronic excessive sex in the past alternates and exhausts the hypothalamus-pituitary-adrenal function. Likely drugs, sex is very addictive due to neuroplasticity. What do you think?

I can see how that makes sense. When i was younger and just discovered it I used to masturbate quite frequently. The problem is with society is there is a stigma talking about it and all that is said is that its fine and completely normal. I thought it was pretty much normal and natural. After 1 or 2 years i started noticing fatigue the following day so id limit myself to once every couple of days. and it just got worse after that xD

13

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 12/10/2008 22:05:14 »

Hey people im still around =)
I have my first session with our university mental health counsellor to talk about this with her. I seem to remember an online form, where users could submit their symptoms and all sorts of information.. Id like to show this to her as i found it very useful =)
could someone please link me?? []

************ is my email

14

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 19/07/2008 22:19:27 »

Hi guys, im still about! I'm going to try and play a more active role in this forum, it seems i only come to you guys when I need comforting. Im up for making that video, that sounds a very good idea to me. Together we can beat this ^^ and the website would be a good way to get together. Imagine if this site were to go down O.O I actually need you guys.

Yukka:ich möchte Sie hier Willkommen heiβen. Mein Deutsch ist keineswegs perfekt, aber ich könnte vielleicht für sie übersetzen. Die wichtigste Sache dass wir tun können ist dieser Thema zu besprechen und wir interessieren uns für ihre Erfahrungen =) Hoffentlich hören wir bald von dir!

That was just a little hello for Yukka guys =) no secret information being discussed here! I said we wanna hear about his/her experiences and stuff

15

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 10/06/2008 11:24:12 »

and the discussion continues xD Man i sure had a lot to catch up on since my last posts. It seems as though this page is getting a bit more precidence in the search results as there seems to be a lot more members joining lately =) I just thought id mention, i tend to have wet dreams in the morning, about 04:00? if thats any help, i heard this is because testosterone is highest in the morning "morning glory" and all that.. but its nice to communicate with people who know what we are talking about. One of the hardest things with this is not being able to talk to people about it!

-hey how are you?
er...good..

And so it happens again and i have 5 exams tomorrow and the academic aspirations for the future become ever more distant =) I liken it to getting beaten down to the floor, picking oneself up only for it to happen again. Each time it gets a little harder to stand up..

16

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 14/05/2008 09:21:42 »

My POIS symptoms are unique, different to when I have done lots of sport. Mine include

Mental Fog, Can't concentrate or think logically, work things out or recall necessary things.
Severe Depression
a little physical fatigue and headache
Large pupils

Actually to mention on that stretching thing i did find it harder to stretch in a pois cycle, and I used to do lots of  hard stretching. I also have pretty bad OCD

And guess what, i had another wet dream last night! and I have an A2 Module tomorrow! Doesn't it just make you glad to feel alive..

17

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 11/05/2008 09:19:32 »

Hi guys, Thank you very much for replies, they mean a lot. Its reassuring to know there are people out there who understand. I had another nocturnal emission last night :/ but as you can see.. Im still here...

I do not know if this has already been posted but i found this article:
http://www.reuniting.info/science/sex_and_addiction
particularly go down to sex's hidden hangover

18

New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 07/05/2008 19:38:25 »

Ive started a POIS cycle again, but for me it takes over a week to recover properly and to get to the point to where I can think right again, and i have exams coming up. I am so close to suicide right now