Naked Science Forum

Life Sciences => Physiology & Medicine => Topic started by: Lewis Thomson on 14/01/2022 10:29:22

Title: How do antiflam tablets not damage the stomach lining?
Post by: Lewis Thomson on 14/01/2022 10:29:22
Carli wants to know an answer to the following.

"Lets assume stomach acid round PH 3. How does an antiflam tablet, that does not have PH anywhere near that, damage the lining of stomach if the same lining is able to withstand the stomach acid?"

What do you think? Leave your answers in the comments below...
Title: Re: How do antiflam tablets not damage the stomach lining?
Post by: Bored chemist on 16/01/2022 09:47:50
Part of the answer is that may anti inflammatory drugs like aspirin are phenols and phenols  denature proteins by interaction with the amide groups.
Title: Re: How do antiflam tablets not damage the stomach lining?
Post by: evan_au on 17/01/2022 09:20:26
Some tablets have an "enteric coating" that protects the stomach from the active ingredient (and vice-versa) until the tablet has progressed into a different part of the digestive system, with a different pH.