Naked Science Forum
Life Sciences => Physiology & Medicine => COVID-19 => Topic started by: Cogreslab on 20/04/2020 18:50:53
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Before antibiotics, UVC blood irradiation was dramatically successful in the 1930s and 1940s against viral infections like viral pneumonia and polio virus. It is” a cure which time forgot” to quote a 1997 paper by Rowen. More recently, Michael Hamblin and a team at Harvard Medical School in a 2016 J Photobiol paper recommended that the intervention, known as the Knott technik after its discoverer, should be reinvestigated as a treatment. The SARS COV 2 virus has a diameter of 120nm and will be resonated to destruction by UVC at around 240nm. The treatment only irradiates about 5 percent of the donor whole blood which is anticoagulated and reintroduced to the circulation via a normal saline drip. From some 6000 applications it has become clear that one outcome of the treatment is a dramatic increase in he oxygen-carrying capability of haemoglobin. It is simple, virtually costless, and can be administered in ten minutes by any competent phlebotomist. Given that a vaccine will take many months to develop, if at all, it is sensible, surely, to re-visit this proven harmless but effective procedure as a promising new treatment for COVID patients?
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It's an interesting idea.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122858/
But...
Blood is opaque.
The SARS COV 2 virus has a diameter of 120nm and will be resonated to destruction by UVC at around 240nm.
That's not how it works.
From some 6000 applications it has become clear that one outcome of the treatment is a dramatic increase in he oxygen-carrying capability of haemoglobin
That's just not plausible.
We know that hemoglobin is already very good at its job and if a simple change (like that brought about by UV) made it better then evolution would have "learned" how to make that change.
” a cure which time forgot”
Time probably had a reason to forget it.
proven harmless
How did the follow ups check on, for example, blood cancers?
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Thanks for comments. I will try to answer them. “Blood is opaque”. Yes the early papers reporting this technique designed a quartz window to allow blood to flow across it thinly in order to optimise exposure. “Sure which time Forgot” was the title of a 1997 paper. “UV was beneficial... nature would have used it. Sunlight kills bacteria for sure (Downes and Blunt, 19th century discovery). Heliobiology won Finsen a Nobel. Nature does use it! Resonance occurs when the object to be resonated has a diameter of half the wavelength. The wave “buffets” the object the same number of times as its frequency. The wave equation relates wavelength to frequency (l =c/f) so the virus and it’s spikes would be “buffeted” billions of times a second. Sorry for using a non technical word There were over 60000 applications of this technique in the 1930s to 1950. I hope you will read the literature, which reports the finding that the oxygen carrying ability of the patients blood was markedly improved. The finding is impirical. All of the early papers and also those more recent are in the public domain without need for Myathenns or any payment.
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To correct some typos. The Cure which Time Forgot was from the title of Rowen’s 1997 paper. not my phrase. Should read 6000 applications, not 60,000! These were without finding any adverse reactions.
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Maybe they should try sound waves of a frequency which would destroy the virus.
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Maybe they should try sound waves of a frequency which would destroy the virus.
OK, obviously that would need to be quite a high power density.
What frequencies did you have in mind?
Remember- it has to be a frequency that's not absorbed by human tissue or you will kill the patient, rather than the virus.
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Maybe they should try sound waves of a frequency which would destroy the virus.
OK, obviously that would need to be quite a high power density.
What frequencies did you have in mind?
Remember- it has to be a frequency that's not absorbed by human tissue or you will kill the patient, rather than the virus.
I was thinking of taking the blood out through a tube and back in and using the sound on the blood passing through the tube.
Some research here https://www.livescience.com/7472-kill-viruses-shake-death.html
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Maybe they should try sound waves of a frequency which would destroy the virus.
OK, obviously that would need to be quite a high power density.
What frequencies did you have in mind?
Remember- it has to be a frequency that's not absorbed by human tissue or you will kill the patient, rather than the virus.
I was thinking of taking the blood out through a tube and back in and using the sound on the blood passing through the tube.
Some research here https://www.livescience.com/7472-kill-viruses-shake-death.html
OK, any idea what the range of 60 GHz sound waves is in blood?
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... The wave “buffets” the object the same number of times as its frequency....
Even if buffeting inactivated all the virus in extracorporeal blood, it would have no effect on the virus in the cells of the body. (e.g. lungs).
UV light can modify the behaviour of lymphocytes (https://www.ncbi.nlm.nih.gov/pubmed/?term=UV+irradiation+lymphocytes), (which are in blood), which when returned to the patient could behave differently as a consequence of UV exposure.
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RD appears to suggest that only the extracorporeal blood is irradiated. But the reinfused blood does not stop radiating immediately after the UVC source is switched off. It continues to irradiate as it circulates to the deepest parts of the lungs, and only resonates objects with a diameter of 120 nm . Organic cells eg lymphocytes, have diameters of several microns and are not resonated.. That is the nature of UV. That is why microwave oven makers ask users to let the irradiated food stand for a few minutes. Otherwise the consumers mouth and gullet might be irradiated.Microwave oven frequency is 2.45 GHz, the optimal frequency for resonating water. A wavelength of UVC is far shorter e.g. 240 nm.
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The reason it is suggested that food should be allowed to stand a few minutes is because superheating sometimes occurs that leads to explosions nothing to do with stored radiation !
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only resonates objects with a diameter of 120 nm .
That's still not how it works.
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RD appears to suggest that only the extracorporeal blood is irradiated. But the reinfused blood does not stop radiating immediately after the UVC source is switched off. It continues to irradiate as it circulates to the deepest parts of the lungs ...
Sounds like you're invoking blood (auto)fluorescence to deliver light into the body,
but I think that only persists for nanoseconds, a millisecond at most, (blood will not travel very far in that time).
In this example the mice are entirely & continuously illuminated with IR light when injected with ICG, which fluorescences in IR ... https://movie-usa.glencoesoftware.com/video/10.1073/pnas.1718917115/video-1