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This is such a crazy disease.... sometimes I feel like it's a curse. My whole life has revolved around this crap..... allways wondering what causes it and how long I can continue to fight it. Well almost a year since my last post on here..... but I think this time I am back for good.
All of this [POIS] really seems related to Dopamine, doesn't it?
with all the cross connections, different POIS sufferers might have weaknesses at different stages of such pathways and yet share very similar symptoms (as we do) because cross-connections in the pathways might ultimately all lead to an imbalance of the same chemical, set of chemicals or affect the same hormone cascade. This might mean different remedies are more effective for some of us than others because the starting cause might be different even though the end result is the same.
Quote from: mellivora on 26/02/2010 11:12:01with all the cross connections, different POIS sufferers might have weaknesses at different stages of such pathways and yet share very similar symptoms (as we do) because cross-connections in the pathways might ultimately all lead to an imbalance of the same chemical, set of chemicals or affect the same hormone cascade. This might mean different remedies are more effective for some of us than others because the starting cause might be different even though the end result is the same. Mellirova, this is a great summary/restatement of this issue. You are right to emphasize that different people might have deficiencies in different parts of the chain, and that therefore they might require different treatments, but that learning about what helps even just one person can be helpful for figuring out more about the overall picture, which can then help others.Also, regarding your point about the 'temporary' nature of the problem (i.e. lasting only a limiting number of days after orgasm)--is there any evidence that would indicate whether it's more likely to result from an excess of something (which is then slowly absorbed/metabolized over the course of a few days) or from a depletion of something (which is then slowly re-produced back to normal levels over the course of a few days). (For instance, in terms of alcohol, the symptoms of intoxication result from an excess of alcohol, which is then gradually absorbed, and the symptoms go away.) Physiologically, given the symptoms of POIS, is one more likely than another? Would there be a way to test or determine this?
AnxietyAny time there is a H. pylori problem or any digestive inflammation (from foods, other digestive infections), the adrenal glands have to produce the stress hormone cortisol. It is common to see either too high or too low levels of cortisol in people with Helicobacter pylori. Each molecule of cortisol has to be made from a molecule of progesterone and over time this leads to a deficiency in progesterone. In women, this often causes mood problems, especially depression, irritability and anxiety. It can also lead to PMS symptoms such as painful menstruation, heavy bleeding or skipping periods altogether.As the adrenal glands make cortisol, other hormones such as DHEA, testosterone and oestrogen can also drop too low, again contributing to depression in men and women. Dr Candace Pert, PhD calls hormones are ‘molecules of emotion’. High or low levels of these molecules can cause emotional imbalances.DepressionAny time there is a H. pylori problem or any digestive inflammation (from foods, other digestive infections), the adrenal glands have to produce the stress hormone cortisol. It is common to see either too high or too low levels of cortisol in people with Helicobacter pylori. Each molecule of cortisol has to be made from a molecule of progesterone and over time this leads to a deficiency in progesterone. In women, this often causes mood problems, especially depression, irritability and anxiety. It can also lead to PMS symptoms such as painful menstruation, heavy bleeding or skipping periods altogether.As the adrenal glands make cortisol, other hormones such as DHEA, testosterone and oestrogen can also drop too low, again contributing to depression in men and women. Dr Candace Pert, PhD calls hormones are ‘molecules of emotion’. High or low levels of these molecules can cause emotional imbalances.Fatigue / Low EnergyYou will no doubt have suffered with ‘the flu’ or a bad cold in the past. If so, you will have experienced how tired such an infection can make you feel. The same goes for a chronic digestive infection like H pylori. If you have a digestive infection of any kind, you will likely feel low on energy because your body will be using lots of energy to fight the infection 24/7.Your appetite may also drop, leading to inadequate intake of food (one of the reasons people lose weight when they are ill). Chronic digestive infections also lead to a condition called adrenal fatigue. Any time there is an infection or digestive inflammation, the adrenal glands have to produce the stress hormone cortisol. If the adrenals become tired, energy levels tend to become depleted, especially in the mid-afternoon. You may also wake up feeling unrefreshed because your body has been fighting the infection overnight.
Sleep problemsMelatonin is a hormone that helps us sleep. Any time there is a H. pylori problem or any digestive inflammation (from foods, other digestive infections) the adrenal glands have to produce the stress hormone cortisol. It is common to see either too high or too low levels of cortisol in people with Helicobacter pylori. High cortisol can disrupt the body’s ability to make melatonin, which can cause insomnia.Each molecule of cortisol has to be made from a molecule of progesterone and over time this leads to a deficiency in progesterone. In women, this can lead to sleep problems. Of course, Helicobacter pylori cause digestive pain, which can also disrupt sleep.
If Helicobacter pylori is present in the stomach for a long time, it damages the parietal cells that produce hydrochloric acid. This leads to low stomach acid, or hypochloridia. When acid is low, it becomes very difficult to digest food. As a result, food sits in the stomach and putrefies, giving off gases and causing a burning sensation in the stomach and/or throat.
My POIS symptoms at this point are not related to intestinal problems or candidiasis. I used to have horrible digestive problems for about ten years--including intestinal candida overgrowth. I tried to "get rid of" candida, with rigid diets and many kinds of anti-fungals (both herbal and drugs). But this backfired on me--the anti-fungals worked to lower the candida levels, but gave me horrible die-off symptoms; then when I stopped the protocols the candida came back on me. Finally, I discovered (through one of those well timed coincidences) that I needed hydrochloric acid, and began taking Betaine HCl with every meal. This was truly like a miracle on my digestive tract! I'd had a very difficult time digesting protein prior to this. My stomach did not produce enough HCl to break it down properly, so it would putrify rather than digest, and I'd end up with a killer migraine and a long night of vomiting my guts out. I was protein starved, very emaciated and exhausted from the nutritional deficiencies I'd acquired. After beginning the HCl, my digestion changed over night. From that point on I could eat protein without a problem. The migraine/puking episodes stopped. I gained weight and kept it on. AND... I no longer had candida. Granted I had stopped consuming as many starches, like potatoes and grains, and was now eating a lot more protein and vegetables, but I'm convinced that the HCl was very much the key to solving the candida problem for me. Once my digestion worked better, candida could not thrive there anymore. However, eliminating candida did not diminish or change the POIS problem. For me the POIS ismore endocrine related, and continues to be so.
SupplementsMany plants have shown an ability to kill H. pylori in the test tube but animal or human research has yet to prove these connections. Among the substances tested in the laboratory and found to have activity against the microbe is garlic, glycyrrhizic acid, Iceland moss, Manuka honey, cinnamon, garlic, capsaicin and Rheum palmatum (rhubarb root). Barry Marshall notes that H. pylori is sensitive to berberine, and that citrus seed extract is moderately effective in eradicating H. pylori. Mastic gum from the Pistacia lentiscus plant, an ancient remedy for digestive problems, is currently being used with some success.
Demo, maybe I should join your Fingertip Issue Club.
Also, I believe I've successfully sent a PM, including my email address, regarding the Research Study PDF.
You all have my sympathy.
Hi!Any ideas, what do You think? ->http://www.reuniting.info/science/articles/acute_dopamine_depletion_causes_psychological_distressRegards
H Pylori can cause an individual to have a Vitamin B12 deficiency. It is also a known contributor to gastritis, ulcers, and it can prevent to stomach from being able to absorb the Vitamin B12 you consume. According to the information on the PCC Natural Markets website, an infection of Helicobacter Pylori, especially in adults will lead to a deficiency of Vitamin B12.One study has found that 56% of those with H Pylori are also anemic due to a lack of Vitamin B12. Taking care of the H Pylori has shown that blood levels improve and Vitamin B12 are higher for 40% of those who have been infected. Some other studies indicate that H Pylori and a Vitamin B12 deficiency are definitely linked. However, eliminating H Plyori doesn't always mean the body will be able to have a higher level of Vitamin B12. Therefore it is important to have it carefully monitored.A study regarding the effects of H Pylori on Vitamin B12 levels can be found in the archives of Internal Medicine (Vol. 160, No. 9, May 8 of 2000). This study involved 138 individuals who were diagnosed with both anemia and a Vitamin B12 deficiency. Each individual in the study completed a Gastrointestinal Endoscopy to determine how severe the atrophic gastritis was. A biopsy was conducted for Campylobacter organisms and a complete medical history was documented. The diagnosis of H Plyori resulted in a combination treatment.The study determined that H Pylori was found in 77 of the 138 patients (56%). They H Plylori infection and the anemia both improved with the assistance of Vitamin B12 supplements in 31 (40%) of the individuals. Therefore, it is reasonable to state that H Plylori is linked to a Vitamin B12 deficiency.The results of various studies have shown that H Pylori damages the stomach cells which prevents it from successfully absorbing the Vitamin B12. Taking care of the H Pylori will help with the level of Vitamin B12 but not in every case. It is therefore essential that you have your Vitamin B12 levels checked at routine intervals if you have ever had H Pylori.You can also find more info on flaxseed oil and requirements for omega. OmegaFlaxSeedOil.com is a comprehensive resource to help individuals gain the benefits of essential nutrition such as flax seed oil, omega 3 and vitamin B12.
New TheoryH. pylori (Helicobacter pylori)Symptoms1. Anxiety2. Depression3. Fatigue / Low Energy
And could H. pylori be the root cause of my sleep difficulties?