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Cells, Microbes & Viruses / Re: Can some one here explain the biology of aging?

« on: 24/04/2022 17:57:03 »

What causes collagen build up? Does scientist know what causes collagen build up? I would think if scientist knew what causes collagen build up there would be drug or gene therapy to counter it.

From what I understand when people get older the skin starts to build up lots of collagen and this is what makes the skin very hard and less elastic.

When person is young the skin is very mice and soft and smooth. It is very elastic.

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Cells, Microbes & Viruses / Re: Can some one here explain the biology of aging?

« on: 17/04/2022 13:17:26 »

when you get older the reason your face and skin get wrinkled is because it becomes hard and less elastic.

Skin ageing is caused in part by TGF-β, which reduces the subcutaneous fat that gives skin a pleasant appearance and texture.

It still does not explain why the skin build up lots of collagen and how to counter it.

When a person is young the skin is nice and smooth and texture is nice and smooth and elastic. When the person gets older the skin is hard and not elastic because of the build up of collagen.

I also read things like free radicals and problems with the mitochondria can cause aging.

So it may not be one or two things but number of things causing aging.

And nice and smooth skin cells is just one of them.

I also hear the cells not dividing or dividing very slow because of the short telomere caps problem.

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Cells, Microbes & Viruses / Can some one here explain the biology of aging?

« on: 15/04/2022 13:51:49 »

I read some where when you are young the skin cells are nice and smooth and elastic but when you get older the reason your face and skin get wrinkled is because it becomes hard and less elastic. Not sure why it get hard and less elastic?

Some thing to do with the human body that replace extracellular protein elastin with less pliable collagen? The build up of collagen and less elastic or less pliable collagen?

Also some thing to do with cells not dividing or dividing very slow because of telomere caps? That the telomeres have a cap and cells stop dividing or are dividing very slow because of the telomeres cap.

Not sure why people when they get older get thin hair or very little hair may be it is some thing to do with person DNA?