Naked Science Forum

Non Life Sciences => Chemistry => Topic started by: EvilFrog on 07/01/2010 13:53:06

Title: Why does glycolysis use glucose-6-phosphate but fructose-1,6-bisphosphate?
Post by: EvilFrog on 07/01/2010 13:53:06

why glucose have to change to glucose-6-phosphate and fructose-1,6-bisphosphate during glycolysis?

Title: Re: Why does glycolysis use glucose-6-phosphate but fructose-1,6-bisphosphate?
Post by: kilgorethecat on 08/03/2010 13:58:34

Adenosine triphosphate (ATP) donates a phosphate group to the 6th and 1st carbons on glucose in a series of enzyme assisted reactions to prepare the molecule to be split in half, forming two smaller molecules each with their own phosphate group.  This phosphate group is essentially a way to store energy in bonds that will later be released and reused by adenosine diphosphate (ADP), and you will end up with a product of more net ATP molecules than what were used to fuel the reaction. 

Title: Re: Why does glycolysis use glucose-6-phosphate but fructose-1,6-bisphosphate?
Post by: Yair Doza on 27/03/2010 20:15:43

another reason is to prevent the glucose leaving the cell. Glucose enter the cell by diffusion through glucose channels. To maintain the gradient the glucose is modified with one organic phosphate - it can not go through the glucose channels any more. The second phosphate and modification are as explained so well in the previous comment.