Naked Science Forum

Life Sciences => Physiology & Medicine => Topic started by: jimmy on 25/09/2003 05:53:15

Title: Statins as anti-osteoporotic drugs
Post by: jimmy on 25/09/2003 05:53:15
Hi,
What are the prospects of statins (HMG-CoA reductase inhibitors) as an anti-osteoporotic drugs? Are they anti-resorptive or anabolic drugs?
Title: Re: Statins as anti-osteoporotic drugs
Post by: Donnah on 03/10/2003 01:51:38
Hi Jimmy, welcome.  I'll see what I can find.  Be patient.
Title: Re: Statins as anti-osteoporotic drugs
Post by: Donnah on 08/10/2003 00:02:38
Hi Jimmy,

Looks like statins may have antiresorptive and anabolic effects on bone.  http://www.ccjm.org/pdffiles/CRUZ402.PDF

There seems to be some confusion regarding various studies.  This is an overview.  There are some interesting links through this site.  http://www.k5thehometeam.com/Global/story.asp?S=1359994   

There is also some concern that statins inhibit CoQ10 synthesis.  http://www.epic4health.com/coqandstatdr.html

Hope that helps.   
Title: Re: Statins as anti-osteoporotic drugs
Post by: chris on 22/01/2004 16:23:52
And now also concern that statins may affect memory :

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&list_uids=12885101&dopt=Abstract

Chris

"I never forget a face, but in your case I'll make an exception"
 - Groucho Marx
Title: Statins as anti-osteoporotic drugs
Post by: Karen W. on 24/11/2009 10:50:46
What are some of the long term effects say of Pravastatin...?
I have been on it for about 2 years now.. I have both osteo and Rhumotoid Arthritis so how would this react to those factors? How does it effect the bone and The memory intrigues me as I have had real trouble there since after my mini stroke.. not like long term stuff but short term.. like I get up to get something and don't get to steps and have forgotten and get confused going back and forth in my head then don't even know what I had been doing or where I was before I found myself standing up confused about ..what?????? LOl Its horrible..