Naked Science Forum

On the Lighter Side => New Theories => Topic started by: smart on 21/12/2015 12:57:42

Title: How can ultrasonic neuromodulation remotely control brain activity?
Post by: smart on 21/12/2015 12:57:42
how could remote control of neuronal populations by ultrasound neuromodulation modify brain activity ?

From wikipedia: 
"Transcranial pulsed ultrasound (TPU) uses low intensity, low frequency ultrasound (LILFU) as a method to stimulate the brain. In 2002, Dr. Alexander Bystritsky first proposed the idea that this methodology contained therapeutic benefits.[1] Beginning in 2008, Dr. William Tyler and his research team from Arizona State University began an investigation and development of this alternative neuromodulation without the harmful effects and risks of invasive surgery. They discovered that this low-power ultrasound is able to stimulate high neuron activity which allows for the manipulation of the brain waves through an external source. Unlike deep brain stimulation or Vagus nerve stimulation, which use implants and electrical impulses, TPU is a noninvasive and focused procedure that does not require the implantation of electrodes that could damage the nervous tissue. Its use is applicable in various fields including but not limited to medical and military science. Although this technology holds great potential to introducing new and beneficial alternatives to conventional brain manipulation, it is a relatively young science and has certain obstructions to its full development such as a lack of complete understanding and control of every safety measure"


http://en.wikipedia.org/wiki/Transcranial_pulsed_ultrasound

www.tylerlab.com/projects/ultrasound

www.public.asu.edu/~wtyler/lab/Curriculum%20Vitae_files/Tufailetal061010.pdf
Title: Re: How can ultrasonic neuromodulation remotely control brain activity?
Post by: RD on 21/12/2015 15:06:56
... Transcranial pulsed ultrasound (TPU) uses low intensity, low frequency ultrasound (LILFU) as a method to stimulate the brain. In 2002, Dr. Alexander Bystritsky first proposed the idea that this methodology contained therapeutic benefits ...

If that doctor is this Californian psychiatrist, then the medical board of California are not happy with his behaviour, nor are some of his patients ....

Quote from: cchroc.org
... On Dec 26th, 2013, Dr Bystritsky (a Russian trained psychiatrist) was reprimanded by the Medical Board of California...
http://cchroc.org/alexander-bystritsky-ucla-psychiatrist-receives-public-letter-reprimand/

Quote from: vitals.com
The overall average patient rating of Dr. Alexander Bystritsky is Below Average ... The rating is 2 out of 5 stars
http://www.vitals.com/doctors/Dr_Alexander_Bystritsky.html


I'd want independent-verification of Dr.Bystritsky's proposition before devoting any time to considering the matter.

[ Hopefully you're not trying to come up with an exogenous mechanism for "thought insertion (https://en.wikipedia.org/wiki/Thought_insertion)"]
Title: Re: How can ultrasonic neuromodulation remotely control brain activity?
Post by: RD on 21/12/2015 15:26:45
Dr. William Tyler ... from Arizona State University

Is not a di$intere$ted-party ...
Quote from: linkedin.com
SynSonix is a privately held company founded in 2009. SynSonix was originally founded by Dr. William Tyler of Arizona State University ... The foundation of SynSonix is its patented technology using pulsed ultrasound to noninvasively and remotely control brain function. SynSonix is focused on developing medical devices designed to noninvasively control brain function for diagnostic and therapeutic purposes for such diseases as epilepsy, chronic pain, traumatic brain injury, Alzheimer's, Parkinson's, depression, brain cancers, and obesity ...
https://www.linkedin.com/company/synsonix-llc

How many cu$tomer$ in America for a non-invasive therapy which could, theoretically, address obesity ?. Who wouldn't want to invest in that technology, if it worked.
Title: Re: How can ultrasonic neuromodulation remotely control brain activity?
Post by: smart on 21/12/2015 16:31:59
How many cu$tomer$ in America for a non-invasive therapy which could, theoretically, address obesity ?. Who wouldn't want to invest in that technology, if it worked.

Social neuroscience is the branch of neuroscience which studies the neural correlates of behavior.

While TPU might not be ready for medical purposes, the military applications of ultrasonic neuromodulation are well defined. Non-lethal population control of thoughts and beliefs through brain stimulation of hippocampal neurons
is an example of the applications this technology could exploit.

Title: Re: How can ultrasonic neuromodulation remotely control brain activity?
Post by: smart on 21/12/2015 17:21:20
"Neural Dust: An Ultrasonic, Low Power Solution for Chronic Brain-Machine Interfaces"

Could synthetic nanoparticles injections in the atmosphere provides a piezoelectric framework for brain-machine
interfaces through ultrasonic transduction of brain waves into electrical signals?

http://arxiv.org/pdf/1307.2196.pdf;

https://en.wikipedia.org/wiki/Ultrasonic_transducer
Title: Re: How can ultrasonic neuromodulation remotely control brain activity?
Post by: smart on 21/12/2015 19:27:05
More evidences towards the use of engineered barium titanate nanoparticles for ultrasonic neuromodulation of neurons:

"Piezoelectric Nanoparticle-Assisted Wireless Neuronal Stimulation.

Tetragonal barium titanate nanoparticles (BTNPs) have been exploited as nanotransducers owing to their piezoelectric properties, in order to provide indirect electrical stimulation to SH-SY5Y neuron-like cells. Following application of ultrasounds to cells treated with BTNPs, fluorescence imaging of ion dynamics revealed that the synergic stimulation is able to elicit a significant cellular response in terms of calcium and sodium fluxes; moreover, tests with appropriate blockers demonstrated that voltage-gated membrane channels are activated. The hypothesis of piezoelectric stimulation of neuron-like cells was supported by lack of cellular response in the presence of cubic nonpiezoelectric BTNPs, and further corroborated by a simple electroelastic model of a BTNP subjected to ultrasounds, according to which the generated voltage is compatible with the values required for the activation of voltage-sensitive channels. "

http://www.ncbi.nlm.nih.gov/pubmed/26168074

Title: Re: How can ultrasonic neuromodulation remotely control brain activity?
Post by: evan_au on 21/12/2015 19:55:41
Quote
Could synthetic nanoparticles injections in the atmosphere provides a piezoelectric framework for brain-machine interfaces through ultrasonic transduction of brain waves into electrical signals?
To transfer power efficiently, you need:
- a good impedance match between transducer and target.
- a transducer that is at least a wavelength in size (they are promoting use of ultrasound at 5.7MHz).

Analyzing it:
- There is a very poor impedance match between the air and body, which effectively blocks ultrasound.
- The impedance match from air to the bone of your skull is even worse
- I expect that there would be a very poor impedance match between synthetic nanoparticles and the air.
- The "nanoparticles" would need to be at least 0.05mm across to produce any significant signal at 5.7MHz; this is quite a large dust particle, which would fall out of the air pretty quickly.
- The battery in your smartphone goes flat after a day - think what will happen to the nanobattery in a high-power ultrasound transmitter!
- To produce particular neurological results, you would need to target it to particular regions of the brain. You would need to provide the hypothetical nanodust with legs (like little nits).

This is why the familiar baby ultrasound is mains-powered, typically uses a transducer at least 5mm across, is held in direct contact with the body, and uses an impedance-matching gel to improve power transfer.

Quote
neuromodulation modify brain activity?
What are you smoking (http://www.abc.net.au/radionational/programs/healthreport/health-risks-of-using-cannabis/7029228)?
Title: Re: How can ultrasonic neuromodulation remotely control brain activity?
Post by: smart on 21/12/2015 20:33:02
Quote
Could synthetic nanoparticles injections in the atmosphere provides a piezoelectric framework for brain-machine interfaces through ultrasonic transduction of brain waves into electrical signals?
To transfer power efficiently, you need:
- a good impedance match between transducer and target.
- a transducer that is at least a wavelength in size (they are promoting use of ultrasound at 5.7MHz).

I'm not sure what means "impedance match". What I believe is that the piezoelectric properties of barium titanate makes it a potential nanotransducer for ultrasonic neuromodulation of brain currents.

Quote
Analyzing it:
- There is a very poor impedance match between the air and body, which effectively blocks ultrasound.
- The impedance match from air to the bone of your skull is even worse
- I expect that there would be a very poor impedance match between synthetic nanoparticles and the air.
- The "nanoparticles" would need to be at least 0.05mm across to produce any significant signal at 5.7MHz; this is quite a large dust particle, which would fall out of the air pretty quickly.
- The battery in your smartphone goes flat after a day - think what will happen to the nanobattery in a high-power ultrasound transmitter!
- To produce particular neurological results, you would need to target it to particular regions of the brain. You would need to provide the hypothetical nanodust with legs (like little nits).

This is why the familiar baby ultrasound is mains-powered, typically uses a transducer at least 5mm across, is held in direct contact with the body, and uses an impedance-matching gel to improve power transfer.
Thanks for this information.  Again, i'm unfamiliar with impedance matching so I guess you believe that nanoparticles must be well characterized/engineered for allowing remote brain activity modifications. 

Quote
neuromodulation modify brain activity?
Quote
What are you smoking?
I'm barely attempting to discover the connections between nanotechnology and social neuroscience.
Title: Re: How can ultrasonic neuromodulation remotely control brain activity?
Post by: mriver8 on 26/12/2015 05:54:05
If this existed would this shield it?
Jem v. the US Navy's latest weapon - Bang Goes th…:
Title: Re: How can ultrasonic neuromodulation remotely control brain activity?
Post by: evan_au on 26/12/2015 12:06:56
Quote from: tkadm30
I'm not sure what means "impedance match".
An example: When you try to see into the water in the daytime, it's pretty difficult, because of the sunlight reflected from the water. This is because air and water have a different impedance for light (light travels faster in air than in water); whenever there is a change in impedance, you get reflections, and some of the energy gets reflected away. The greater the impedance change, the greater the amount that is reflected away.

Sound travels at different speeds in air and water (faster in water than in air). A different speed is one characteristic when a wave enters a material with a different impedance. The inner ear is filled with fluid, while the air is filled with... air. In the case of the audible noise source in the video above, the outer ear collects and feeds sounds into the middle ear and inner ear, transforming the impedance so that the ear is exquisitely sensitive to sound in the audible range.

Another contrasting example is the flute and saxophone. The bell of the saxophone performs an impedance matching function between the mouthpiece and the air, resulting in much more efficient transfer of power from the mouthpiece to the air. Saxophone vs Flute: Saxophone always wins.

So in the case of ultrasound-emitting nanoparticles, it takes a lot of energy to distort the solid nanoparticles, but very little of this energy is transferred to the air (because of impedance mismatch). Any vibration that does make it into the air then spreads out in space. Most of the ultrasonic energy that strikes a human head will just bounce off again into the air (impedance mismatch again). A lot of the ultrasonic energy that finds its way into the scalp will bounce off the much stiffer bone of the skull.

So to get ultrasound into the body, it is best for the source to be directly in contact with the body, without an intermediate air barrier. This makes remote control via ultrasound very inefficient (even if it were possible using direct mechanical contact).
Title: Re: How can ultrasonic neuromodulation remotely control brain activity?
Post by: mriver8 on 28/12/2015 15:03:15
Duel layered with an insulator made up of a polyhedral vacuum cell structure?

http://m.bonanza.com/listings/masei-610-storm-trooper-motorcycle-helmet-white-st610-s-m-l-xl/251464746?gpid=76984043821&gpkwd=&goog_pla=1&gclid=CjwKEAiA2IO0BRDXmLndksSB0WgSJADNKqqog8VA_UpumQ4elPjiH7gbfI8LUU41_JCjhm7Amt-M6xoCl_Tw_wcB
Title: Re: How can ultrasonic neuromodulation remotely control brain activity?
Post by: smart on 03/03/2018 21:21:32
ultrasonic side channels in mobile devices can operates in the 50-60 kHz range.
Title: Re: How can ultrasonic neuromodulation remotely control brain activity?
Post by: Bored chemist on 03/03/2018 21:25:39
Buy a bat detector, and prove there's a real story, or keep quiet.
Title: Re: How can ultrasonic neuromodulation remotely control brain activity?
Post by: Tobias Claren on 08/02/2019 22:22:49
Hello.

Are there DIY projects to build a "thinking cap"?
There are some users of TcDCS, but that is the most primitive and inaccurate technology
1. Transcranial Direct Current Stimulation.
2. Transcranial Magnetic Field Stimulation.
3. Transcranial Ultrasound Stimulation <= The holy grail, deep-focusable etc..

Is it possible to buy suitable focusable capacitive micromachined ultrasonic transducers ("CMUTs")?
Where can I buy it?

Is this the same technology ?:
youtu be/kaoO5cY1aHk

We need a helmet with lots of CMUT.
Or (cost and effort) a helmet with locally movable CMUT emitters.

And a electronic, that controls strength, frequenzy, pulse rate, focus (depth) etc..


Early military experiments:
science.dodlive mil/2010/09/01/remote-control-of-brain-activity-using-ultrasound/