Naked Science Forum

Life Sciences => Cells, Microbes & Viruses => Topic started by: scientizscht on 16/10/2019 23:08:01

Title: How is DNA sequencing done?
Post by: scientizscht on 16/10/2019 23:08:01

Hello!

Can someone describe in comprehensive and simple way how DNA sequencing is done now that it costs a thousand to do it?

thanks!

Title: Re: How is DNA sequencing done?
Post by: scientizscht on 19/10/2019 22:05:12

Anyone?

Title: Re: How is DNA sequencing done?
Post by: evan_au on 19/10/2019 23:14:33

You could listen to the most recent Naked Genetics podcast (30 minutes):
https://www.thenakedscientists.com/podcasts/naked-genetics/quadrillions-sequencing-uk-biobank

Or you could start here: https://en.wikipedia.org/wiki/DNA_sequencing

Techniques are advancing rapidly - I've heard it said that the cost of sequencing is halving about every 9 months.
- So only the general principles will be valid in 3 years time.

Title: Re: How is DNA sequencing done?
Post by: scientizscht on 20/10/2019 15:52:01

Quote from: evan_au on 19/10/2019 23:14:33

You could listen to the most recent Naked Genetics podcast (30 minutes):
https://www.thenakedscientists.com/podcasts/naked-genetics/quadrillions-sequencing-uk-biobank

Or you could start here: https://en.wikipedia.org/wiki/DNA_sequencing

Techniques are advancing rapidly - I've heard it said that the cost of sequencing is halving about every 9 months.
- So only the general principles will be valid in 3 years time.

What are these general principles please?

Title: Re: How is DNA sequencing done?
Post by: evan_au on 20/10/2019 23:28:40

Quote from: scientizcht

What are these general principles please?

Quote from: evan_au

You could listen to the most recent Naked Genetics podcast (30 minutes):
https://www.thenakedscientists.com/podcasts/naked-genetics/quadrillions-sequencing-uk-biobank

Or you could start here: https://en.wikipedia.org/wiki/DNA_sequencing