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Life Sciences => Cells, Microbes & Viruses => Topic started by: scientizscht on 28/01/2020 19:50:48

Title: What happens to the T cells after they have bound to a target?
Post by: scientizscht on 28/01/2020 19:50:48

Hello

So T cells have membrane receptors that bind to specific antigens.

What happens afterwards? I assume cytokines are released by the T cell? What else is happening? Do the T cells detach or stay bound? What is their fate?

Thanks!

Title: Re: What happens to the T cells after they have bound to a target?
Post by: Hayseed on 30/01/2020 16:58:46

I have no idea.  But if I were a T cell, while attached, I would turn myself inside out, and engulf and absorb the intruder.

Title: Re: What happens to the T cells after they have bound to a target?
Post by: Spam2 201221 on 16/12/2021 12:02:01

When attached to its target cell, a cytotoxic T cell can use ways to kill it, which together work by encouraging the target cell to destroy itself through apoptosis.

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Title: Re: What happens to the T cells after they have bound to a target?
Post by: evan_au on 18/12/2021 09:45:43

There are a variety of T-Cell types which work together in various ways, by:
- Killing infected cells
- Recruiting more immune cells to fight the infection
- Suppressing an overactive immune response

The different T-Cell types are most easily characterised by the T-Cell receptor proteins on their surface.
- One of these proteins, "CD4" became well-known as the key by which HIV attacks the immune system in AIDS.

See: https://en.wikipedia.org/wiki/T_cell