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Non Life Sciences => Chemistry => Topic started by: scientizscht on 08/09/2020 20:34:37

Title: How to determine the right buffer concentration?
Post by: scientizscht on 08/09/2020 20:34:37

Hello

In a solution that a reaction will take place and produce an acid, how can I calculate the needed buffer salt mass to be added to maintain the pH?

I know the pH needed and the final acid concentration and pKa.

I also know the buffer salt pKa.

How can I find out the optimal salt concentration?

Thanks

Title: Re: How to determine the right buffer concentration?
Post by: chiralSPO on 08/09/2020 21:05:33

What pH do you need to maintain, and how narrow of a range do you need to maintain? And how similar is the pH to the pKa of your buffer? And how far away is the acid pKa?

Title: Re: How to determine the right buffer concentration?
Post by: Bored chemist on 08/09/2020 21:29:27

Quote from: scientizscht on 08/09/2020 20:34:37

How can I find out the optimal salt concentration?

Quote from: Bored chemist on 04/09/2020 12:59:54

Quote from: scientizscht on 04/09/2020 12:48:19

How can I calculate the pH that will be formed

https://en.wikipedia.org/wiki/Henderson%E2%80%93Hasselbalch_equation

Title: Re: How to determine the right buffer concentration?
Post by: scientizscht on 08/09/2020 23:46:24

Quote from: chiralSPO on 08/09/2020 21:05:33

What pH do you need to maintain, and how narrow of a range do you need to maintain? And how similar is the pH to the pKa of your buffer? And how far away is the acid pKa?

pH needs to be 7.2-7.6
buffer is di-Sodium hydrogen phosphate dihydrate with pKa1=2.1 pKa2=7.2 pKa3=12.6
Acid pKa=3.6

What would be the output of these?