Naked Science Forum

Life Sciences => Physiology & Medicine => Topic started by: jfoldbar on 21/07/2021 01:53:20

Title: what was the first mrna vaccine?
Post by: jfoldbar on 21/07/2021 01:53:20

i got reading about history of vaccines, and learned that we seem to be at a new age of vaccine manufacturing. now using mrna vaccines.
im curios, is covid the first of this type of vaccine, or have there been other vaccines made via mrna?

Title: Re: what was the first mrna vaccine?
Post by: Origin on 21/07/2021 03:20:24

The covid 19 vaccine was the first mRNA vaccine used in large scale phase III trials.

Title: Re: what was the first mrna vaccine?
Post by: evan_au on 21/07/2021 11:55:48

Research into mRNA vaccines has been underway for about 30 years.

The Gates Foundation pumped tens of $million into the research, in the hope of making flexible vaccines for neglected tropical diseases.
- COVID-19 was the impetus that brought them to mass market
- Ironically, the current generation of mRNA vaccines are not heat stable, and need to be kept in extreme cold conditions, which rules them out for most tropical countries
- But I'm sure researchers are working on ways to stabilise them

See: https://en.wikipedia.org/wiki/RNA_vaccine#Early_research