Naked Science Forum

Life Sciences => Physiology & Medicine => Topic started by: Mustang on 24/09/2021 02:54:17

Title: Ab + blood type and AstraZeneca VITT
Post by: Mustang on 24/09/2021 02:54:17

Does anyone know what the distribution of blood types was in the vaccine thrombocytopenia cases?
I’m AB+ which is apparently more susceptible to thrombosis.
Therefore I may be at increased risk of this post vaccine complication?

Title: Re: Ab + blood type and AstraZeneca VITT
Post by: Colin2B on 24/09/2021 09:30:29

I haven’t seen anything linking blood type and ITP. Two recent studies showed those most at risk from ITP were older, with an average age of 69 years, and had at least one underlying chronic health problem such as coronary heart disease, diabetes or chronic kidney disease.
All 11 patients, as well as another 17 for whom the researchers had blood samples, tested positive for antibodies against platelet factor 4 (PF4). These antibodies are also observed in people who develop heparin induced thrombocytopenia. None of the patients had received heparin before their symptoms started.
The German study added: “Whether these antibodies are autoantibodies against PF4 induced by the strong inflammatory stimulus of vaccination or antibodies induced by the vaccine that cross-react with PF4 and platelets requires further study”

I’ll ask @chris if he can comment, he may have more detail.