Naked Science Forum
Life Sciences => Physiology & Medicine => Topic started by: Zer0 on 23/10/2021 19:36:53
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" Superbug: : An informal term for a bacterium that has become resistant to antibiotics that usually are used to treat it, such as methicillin-resistant Staphylococcus aureus (MRSA) or any multidrug-resistant bacterium. "
Dated - 29-Mar-2021.
Is this Real?
(Does seem Official)
But then, Why do i not hear about people passing away due to a
" SuperBug " ?
Ps - Surely the Pharmaceutical Giants will find a Solution for this soon, Right?
🤞
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MRSA is certainly real.
https://en.wikipedia.org/wiki/Methicillin-resistant_Staphylococcus_aureus
But then, Why do i not hear about people passing away due to a
" SuperBug " ?
Did you look?
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/850521/hcai_fatality_report_201819.pdf
"In 2018/19, 805 MRSA bacteraemia cases were reported in England. Information on mortality was available for ~97% (n= 779) of these cases (Table S13). There were 191 deaths within 30 days of an MRSA bacteraemia "
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Surely the Pharmaceutical Giants will find a Solution for this soon, Right?
We hope so, but there's no guarantee.
It would help if we stopped over- prescribing antibiotics.
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There is an ongoing war between bacteria and fungi, using various antibiotic chemicals. So there are certainly additional antibiotics in nature.
The problem is that we can only culture a small fraction of these microbes in the lab (or factory). In nature, microbes tend to live in ecosystems, sharing resources and waste products with other microbes, and we can't replicate that ecosystem in the lab - especially if we want to guarantee the purity of our factory production line.
One approach was to take a small soil sample, dilute it and spread it across many pages of a book whose leaves were a thin, permeable membrane (with pores too small to allow a microbe to pass) - and then bury it back in the soil. This allows microbes to pass resources around, while growing a mono-species colony on each page whose genetics and antibiotic properties can then be studied in the lab.
For volume production, the relevant genes would need to be copied into a factory-friendly microbe - and hopefully, it wouldn't kill the factory microbe!
If an antibiotic occurs in nature, then there are certainly defenses against that antibiotic in nature. The experience is that antibiotic resistance appears in humans within 1 or 2 years of widespread usage of a new antibiotic. It costs $ billions and perhaps 10 years to bring a new antibiotic to market, and then it loses effectiveness within a few years - that is not a profitable product, so Big Pharma companies have largely moved out of antibiotics, focusing on chronic diseases like blood pressure medication.
So, really, it comes back to responsible use of antibiotics, and changing the economics of antibiotic development and approval.
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Many years ago, my great aunt had MRSA. She ended up being okay. I recall that MRSA was also mentioned as a concern when I had an abscess on my leg drained back in 2008. That turned out not to be the cause of infection for me, fortunately. It's certainly a real thing.
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Surely the Pharmaceutical Giants will find a Solution for this soon, Right?
We hope so, but there's no guarantee.
It would help if we stopped over- prescribing antibiotics.
I keep hearing " Vegans " making alot of Noise on this issue.
They Use the notion that Excessive Antibiotics are fed to cattle & farm animals to keep them healthy & to make them grow fatter quickly.
Considering, We now have a global interlinked market...
Beef & Milk from Brazil, India, Australia or elsewhere does reach out to other countries.
So...agreeing on " SuperBug " being a Reality.
Then, do such Excessive Antibiotics also get thru into the byproducts, like say chicken meat, eggs & milk?
Also...farming & agriculture has Not as yet picked up on the
" All Organic " trend worldwide.
Third world countries seem to use Excessive chemicals to keep crops safe & do whatever it takes to prevent harvest from failing.
So...do all such Excessive Chemicals make their way into food grains, pulses & fruits?
I recently heard that there would be more Plastic in the Oceans vs the amount of Fish by 2050.
(Does Not seem Factual or Real)
But considering, work on Plastic eating Bacteria seems Stalled.
And most plastics degrade into finer minute particles.
So...is there Really Plastic in the Fish Meat?
My home water purifier has Plastic tubes, does it slowly n steadily keep dissolving micron quantities of it, due to the steady flow of water?
(If a river can cut thru rocks, then what's a tube)
So...am i drinking micro mini microns of plastic?
Ps - I surely breathe poison with every breath, that I'm quite sure of.
😷
(Not referring to the virus)
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Many years ago, my great aunt had MRSA. She ended up being okay. I recall that MRSA was also mentioned as a concern when I had an abscess on my leg drained back in 2008. That turned out not to be the cause of infection for me, fortunately. It's certainly a real thing.
Hi!
😊
Your Great Aunt must have been guarded over by Higher Powers.
(Extremely Lucky)
👍
You yourself seem to have had your fair share of Luck too.
👍
Ps - Please be a bit more self caring & self preserving & don't push your luck.
👷
(Helmets/Headgear should be made Compulsory for All Mods)
🤞
Tc!
(I stopped using all plastic water bottles. I used any plastic bottle before, then i switched to the ones internationally proclaimed to be made of a different form of plastic that wouldn't dissolve by holding hot water...but now i simply stopped n use a metal flask.)
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Your Great Aunt must have been guarded over by Higher Powers.
Specifically, doctors.
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do such Excessive Antibiotics also get thru into the byproducts, like say chicken meat, eggs & milk?
I don't think that eating the residual antibiotics in the animal is the major concern - antibiotics are rapidly excreted and/or broken down in the body.
A larger concern is that this farming technique feeds animals on low levels of antibiotics; not enough antibiotics to kill all the microbes, because animals (and humans) need a microbiome to help digest their food.
- However, this environment, those microbes which are more resistant to this antibiotic will thrive, while those that are susceptible will die - evolutionary pressure.
- That means that antibiotic resistance will quickly increase in such an environment: Bacteria engage in "Horizontal gene transfer", where useful genes are passed between different species of bacteria
- A combination of antibiotic resistance and a bacteria that is dangerous to humans is an even more dangerous combination.
People working closely with animals are more likely to pick up microbes from them - including antibiotic-resistant microbes.
- And people who eat the meat will tend to pick up antibiotic-resistant bacteria from the food, especially if it is not properly cooked.
There is a similar concern about increasing antibiotic resistance in farm soil (antibiotic-rich urine) and streams (due to antibiotic-rich farm runoff).
Colonization by antibiotic resistant bacteria is not in itself particularly dangerous - until the bacteria get into a sore or the bloodstream, and then our favorite tools for dealing with bacteria are suddenly ineffective.
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👷
(Helmets/Headgear should be made Compulsory for All Mods)
🤞
Tc!
Thick skins are issued as standard 8)