Naked Science Forum

Non Life Sciences => Chemistry => Topic started by: david77 on 09/12/2019 10:35:10

Title: How do I identify this molecule we've made?
Post by: david77 on 09/12/2019 10:35:10
So I am in organic chemistry 2. Basically we synthesized an unknown dipwprice using EDCI HCL. We were assigned two amino acids, one a boc protected amino acid where the r side chain be one of the 20 amino acids and an amino acid methyl ester hydrochloride where the Rain side chain can once again be one of the 20 possibilities. Based on my spectra I can see I have an aromatic present and two methyls. In terms of aromatic I strongly believe I have phenylalanine present and in terms of the other amino acid there are only three that have two methyls and they are valine, leucine, and iso leucine and of those I believe it is valine. Just wanted to know what you guys think about what I believe it is and if itís correct. Thanks a ton for reading my long post.

Title: Re: How do I identify this molecule we've made?
Post by: chiralSPO on 10/12/2019 18:14:15
I can't answer based on the info provided... phenylalanine, tyrosine, and tryptophan all have aromatic portions (histidine may also have shifts in this region)--analysis of the relative integration and symmetry will determine which it is.

Differentiation of valine, leucine, and isoleucine can be done based on coupling patterns. Also, you mention seeing two methyls, but it is not clear from the post that they are different from the methyls that come from the methyl ester and Boc groups. Also, (apologies if you have already considered this) could the apparent two methyls be the one methyl of alanine, split into a doublet by the neighboring proton?