« on: 07/10/2017 11:50:18 »
Acidity causes your cells to mutate, disrupts the normal metabolism, causes the cells to break off to the blood stream and metastase.
Are you actually serious with this nonsense?
This is a science forum.
Let's see some evidence [like peer-reviewed.... in actual journals].
Last I checked, DCA's limited role in cancer supression involved countering the Warburg effect - which enables cancer cells to avoid excess ROS-generation from mitochondrial respiration.
1) Why acidity promotes oncogenesis?
"Warburg effect—increased glucose consumption, decreased oxidative phosphorylation, and accompanying lactate production—are also distinguishing features of oncogene activation."
2) Why acidity distrups normal cell metabolism?
A) Read the same article above.
B) Check a legit biochemistry textbook and look up on how pH changes prevent the normal binding of an enzyme and the substrate. Then sit and think for a minute how this affects the speed of intracellular chemical reactions. Look up what "metabolism" is and what importance do enzymes have in its harmony.
3) Article on why low PH promotes cancer invasion?
Took me five minutes to find scientifical arguments to back up my statement.
How DCA works ? I have already provided tons of information on that but I can repeat it again.
(Read https://www.cancertreatmentsresearch.com/dichloroacetate-dca-treatment-strategy/ again, the guy named Daniel provides links to every statement he makes, why haven't you read it yet and continue to discuss about it ? )
Basically, DCA does this:
Inhibits PDK --> Cancer cells reduce their Warburg effect, normal metabolism is returned, less pyruvate to lactic acid, more pyruvate to the H. Kreb's cycle --> the cell starts to produce energy more in an aerobic way, less in an anaerobic way --> tons of benefits such as:
A) More ROS are generated when oxygen is used in the Kreb's cycle. This inhibits tumour growth and promotes apoptosis - the natural chain of death for damaged cells.
B) Reduces lactid acid --> reduces the acidity (low PH) in cancer cells. We already covered up why low PH is bad for your cells and is good for cancer.
C) Less acidity in the tissues - less pain for people with tumours.
There are more intracellular things going on with the help of Dichloroacetate, I wouldn't quote the articles I've posted so far. Please read them before disagreeing.
Let me ask you a sincere question.
Have you ever studied biochemistry, physiology and oncology ?
Yes? Then go refresh your memory. What we are talking about is completely logical and has tons of articles which support these claims.
No ? Then why are you throwing insults accusing me of spreading nonsense?
Keep it professional. Accuse someone of nonsense when you're sure that you understand what you are talking about.