I usually just take a claritin 24-hour antihistamine about an hour before sex. I don't notice POIS if I take claritin. I am just a bit drowsy but I guess that is normal while on an antihistamine plus post-orgasm.Hey GC, have you tried any other antihistamines by chance? I have tried cetrzine and zirtec, for hayfever relief. They were good, but I have to admit I never noticed any significnat benefit with pois. I actually think it might have helped things a bit with brain fog but it certainly no omg effect.
I have tried Ceterizine (whatever you call it), but that was taken after my orgasm and it didn't do much. Other than that I have only tried claritin 24-hour at least an hour before sex.