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One thing I am absolutely secure, when I have an orgasm I feel almost inmediately that something weird happens in my stomach. I feel like my organism whants to sweep stomach contents to intestine, and that get manifested with fatigue and bad mood. I think that may be some substance poured inside by the orgasm mechanism produce this effect. The process I described it last few days and it is acompanied by other common Pois symthoms that I think are result of that process. And not necessarly having diarrea, it is not my case, I start to get very constipated, wich it helps to get worse others symthomps, like to much fatigue, headaches, swollen nose, greasy nose, sweats, get hungry, specially need for sugar foods somethimes or big meals, little of acne, hard hair hard to comb, among many others.
But this Forum, to me, is an incredible breakthrough. Prior to the Forum, we had absolutely nothing. Now we have hundreds of focused pages chock full of fascinating personal history and even some successes in the cure department. To some degree, I attribute my partial cure to this Forum in that it raised my awareness of possible contributors and alleviants of POIS.
Aight people, I just sent the letter for OHSU, so cross your fingers.
(PS. I aim to have the form up and accessible for us this week. I think it will be a great way to quickly organize and compile our information for researchers).
This is by far the best place I've found in about 10 years of many google searches.
I am really impressed by us! We are so wonderfully relentless.   
Hope this helps. For me it's only confusion.
martin88I feel the same as you, almost exactly the same kind of problem. I am an athlete, and POIS takes my performance down to about 20% of my abillity. Very annoying!
Why can't I just have peanut butter and jelly sandwiches? They cured _everything_ when I was a kid.