Can Artificial Sweeteners make rats fat?

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Can Artificial Sweeteners make rats fat?
« on: 12/02/2008 13:52:01 »
Not sure if this should be under Physiology, or Zoology, since it is about rats, but trying to model human conditions.
A study which showed that rats fed on artificial sweetener still put on weight has baffled researchers.

Scientists from Purdue University in the US now believe that a sweet taste followed by no calories may make the body crave extra food.

Their research, published in the journal Behavioral Neuroscience, found that rats fed sugar subsequently had lower appetites.

But nutritionists say that low-calorie sweeteners are still best for health.

Conventional wisdom says that, as part of a calorie controlled diet, artificial sweeteners can help people lose weight or keep it off.

But the Purdue study turns that wisdom on its head.

They gave different yoghurt to different groups of rats, some sweetened with sugar, and some with saccharin.

They were then given a plentiful supply of food, and the researchers observed the results.

The saccharin-fed mice ate more calories, put on more fat, and gained more weight than their sugar-fed counterparts.

They did not make any attempt to cut back on their food later to regulate their weight.

Sweet expectations

The researchers wrote in the journal: "The data clearly indicate that consuming a food sweetened with no-calorie saccharin can lead to greater body-weight gain and adiposity than would consuming the same food sweetened with higher calorie sugar."

One theory, they said, was that, in normal conditions, the arrival of a sweet taste in the mouth helped prime the metabolism for the arrival of a calorie-heavy, sweet meal into the digestive system.

When the meal does not arrive, they said, the body may get confused and have more trouble regulating its appetite when other food is around.

They said that if this were the case, other low-calorie sweeteners such as aspartame, sucralose and acesulfame could have a similar effect.

A spokesman for the British Nutrition Foundation said the study findings were "interesting", but did not prove that artificial sweeteners could be counterproductive in dieting humans.

"This needs far more research - as studies in humans have shown that low-calorie sweeteners can help people lose weight."
« Last Edit: 05/03/2008 09:08:10 by Karen W. »


Offline Karen W.

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Re: Can Artificial Sweeteners make rats fat?
« Reply #1 on: 12/02/2008 17:09:47 »
I have actually tested this on myself for almost a year, I used artificial sweeteners and I gained 50 lbs... The doctor then said that she would prefer that I not use artificial sweeteners and just use regular sugar and do the same cut back with food consumption.. within a short period of time my food cravings stopped being so crazy and I was able to slowly over three months get back down to the size I was before I started dieting... so for me it did make a difference! The artificial sweeteners made me feel unsatisfied with my food intake. Craving more of the artificially sweetened foods and carbs... But when I stopped I found that that added weight disappeared and I plateaued. For about a year I stayed at 351 pounds. That is when I started in the forum almost three years ago.. I did was able to loose using the zeta and support of the thread and others.. I am still down..110 lbs.. since 2005, but I gained 22 pounds back over the last year, and in the last two months have taken it off again. and am left at 110 as a loss.

I really believe there is something to it. I know longer use the zeta and still I have maintained this weight.. I am very inactive now so hopefully with recovery from illness I will gain some exercise ability again and be able to move down some more.

I felt as if the artificial sugar just made me crave sweets even more.. especially high sugar carbs.. I know longer have those crazy cravings like that. an occasional craving but not like before and I believe that eliminating the artificial sweeteners helped me a lot!
« Last Edit: 12/02/2008 17:11:40 by Karen W. »

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