The Naked Scientists
  • Login
  • Register
  • Podcasts
      • The Naked Scientists
      • eLife
      • Naked Genetics
      • Naked Astronomy
      • In short
      • Naked Neuroscience
      • Ask! The Naked Scientists
      • Question of the Week
      • Archive
      • Video
      • SUBSCRIBE to our Podcasts
  • Articles
      • Science News
      • Features
      • Interviews
      • Answers to Science Questions
  • Get Naked
      • Donate
      • Do an Experiment
      • Science Forum
      • Ask a Question
  • About
      • Meet the team
      • Our Sponsors
      • Site Map
      • Contact us

User menu

  • Login
  • Register
  • Home
  • Help
  • Search
  • Tags
  • Member Map
  • Recent Topics
  • Login
  • Register
  1. Naked Science Forum
  2. Life Sciences
  3. Cells, Microbes & Viruses
  4. Could you inject a donor X chromosome into an ovum?
« previous next »
  • Print
Pages: [1]   Go Down

Could you inject a donor X chromosome into an ovum?

  • 1 Replies
  • 4546 Views
  • 0 Tags

0 Members and 1 Guest are viewing this topic.

Offline aruna

  • First timers
  • *
  • 1
  • Activity:
    0%
    • View Profile
Could you inject a donor X chromosome into an ovum?
« on: 02/05/2008 08:25:58 »
Anu asked the Naked Scientists:
Could you inject a donor x-chromosome into a recipient ovum? What would happen?
What do you think?
Logged
 



Marked as best answer by on 12/02/2021 05:04:42

Offline chris

  • Naked Science Forum King!
  • ******
  • 7947
  • Activity:
    2.5%
  • Thanked: 274 times
  • The Naked Scientist
    • View Profile
    • The Naked Scientists
  • Undo Best Answer
  • Could you inject a donor X chromosome into an ovum?
    « Reply #1 on: 03/05/2008 09:28:25 »
    I'd say yes you could, because that's effectively how cloning works with the exception that in this instance the entire genome (all chromosomes) is injected rather than just one.

    Scientists have also recently produced miniature artificial chromosomes which can be injected into mouse embryos where they are propagated into the cell progeny like any other chromosome.

    So my prediction would be that you could inject an X chromosome into a cell and, just like multiple X chromosomes in human syndromes like Kleinfelter's, the bulk of the genes on either the native X chromosome, or the one you had injected, would be inactivated. Which was targeted for inactivation in different cells would be random, according to the Lyon hypothesis.

    Chris 
    Logged
    I never forget a face, but in your case I'll make an exception - Groucho Marx - https://www.thenakedscientists.com/
     



    • Print
    Pages: [1]   Go Up
    « previous next »
    Tags:
     

    Similar topics (5)

    In X-linked diseases, how does the a cell identify which chromosome is faulty?

    Started by Curious AshBoard Physiology & Medicine

    Replies: 2
    Views: 4112
    Last post 06/08/2008 00:10:07
    by chris
    What is the effect of fusion of chromosome 2 in human nuclear cell?

    Started by hamdani yusufBoard Plant Sciences, Zoology & Evolution

    Replies: 8
    Views: 3305
    Last post 22/11/2017 03:28:30
    by hamdani yusuf
    Is there a gene for colour differentiation in humans? If so in which chromosome?

    Started by LemonpieBoard Cells, Microbes & Viruses

    Replies: 1
    Views: 2915
    Last post 16/03/2011 19:40:57
    by Lemonpie
    If you inject a human enzyme in a human, will it cause immunological reaction?

    Started by scientizschtBoard Chemistry

    Replies: 1
    Views: 803
    Last post 13/02/2019 19:45:25
    by evan_au
    What is the convention for naming chromosome loci?

    Started by DoctorBeaverBoard Physiology & Medicine

    Replies: 9
    Views: 14952
    Last post 29/09/2011 10:28:20
    by chris
    There was an error while thanking
    Thanking...
    • SMF 2.0.15 | SMF © 2017, Simple Machines
      Privacy Policy
      SMFAds for Free Forums
    • Naked Science Forum ©

    Page created in 0.103 seconds with 37 queries.

    • Podcasts
    • Articles
    • Get Naked
    • About
    • Contact us
    • Advertise
    • Privacy Policy
    • Subscribe to newsletter
    • We love feedback

    Follow us

    cambridge_logo_footer.png

    ©The Naked Scientists® 2000–2017 | The Naked Scientists® and Naked Science® are registered trademarks created by Dr Chris Smith. Information presented on this website is the opinion of the individual contributors and does not reflect the general views of the administrators, editors, moderators, sponsors, Cambridge University or the public at large.