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Let me approach this from a different angle with a relative analogy. Say someone was on a diet. The goal of losing weight has been in the works for some time and means a lot to them. After planning they start diet. After a few weeks they cheat on the diet. The people who created the most lofty goal to succeed, will feel the strongest feelings of disappointment, as well as other possible feelings. We could call this emotional withdrawal, Post Cheating on the Diet Syndrome or PCOTDS. In the case of PCOTDS, this is not based on a chemical imbalance, although a chemical imbalance may appear up, later, if we remain depressed. We can treat the symptoms of PCOTDS but this does not reach the cause. Rather the foundation affect stems from subroutines in the mind. We can only be disappointed and depressed, if we previous had a lofty image of a goal, we did not achieve. In this case, the imaginary positive self image of being on the diet, may have associated extrapolations of becoming more beautiful, more confident and happier. The opposite of that ideal is more ugly, more withdrawn and more depressed. If one sets a strong line in the sand, via a subroutine, there may not be shades of gray in terms of the output reaction. The question I would ask is, what did/do women with POIS expect from an orgasm? What is the image of the distant goal that this dynamics is/was suppose do lead to? Is it morning sickness? Is it flying on a cloud of joy? Is it love? I don't mean to stereo-type, but this appears to be an open minded group discussion. In my experience, many, but not all female minds, seem to work more like an on-off switch, instead of a variable switch. This is partly connected to perfection, which has only one way. For example, the abused wife may love her abusive husband, unconditionally; on switch. Instead of pro-rating her love in shades of gray that average her abusive husband's good side wth his bad side, she may want to see only the good. This can be to her peril. If they divorce, instead of taking an average of the good he did over the years, and the bad he also did, she may only feel 100% negativity; off switch. The on-off switch of the female mind appears to be connected to not only perfection, but also to unconditional love and maternal instincts. Unconditional love does not have shades of gray. The mother does not pro-rate the love for a child who has both problems and brings her joy; shades of gray in her love. She will keep the switch on. This female line in the sand, could explain why POIS is more of a lady thing. The reflection sub-routine symptoms will be stronger. I come back to the questions, what is/was the ideal image of an orgasm; line in the sand?