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The steroid psychoses we saw presented as a spectrum psychosis with symptoms ranging from affective through schizophreniform to those of organic brain syndrome. No characteristic stable presentation was observed in these 14 patients, but the most prominent symptom constellation to appear during the course of the illness consisted of emotional lability, anxiety, distractibility, pressured speech, sensory flooding, insomnia, depression, perplexity, agitation, auditory and visual hallucinations, intermittent memory impairment, mutism, disturbances of body image, delusions, apathy and hypomaniaSince our study, several other critical reviews of the literature and new studies have become available. This newer literature provides longitudinal insight into the nature of steroid induced mental change. The incidence of steroid psychosis varies widely in the literature ranging from 13 to 62%, with a weighted average of 27.6% for some steroid induced mental change, the vast majority of which are mild to moderate and do not herald the development of a full-blown psychosis or affective syndrome. The incidence of a severe psychiatric syndrome in the more than 2,500 patients reported in the literature ranges from 1.6 to 50% with a weighted average of 5.7%.
TABLE 2 Adverse Effects of Steroid Therapy and Cautions. Neuropsychiatric:Headache, vertigo, seizures, increased motor activity, insomnia, mood changes, psychosis. Use with caution in patients with convulsive or psychiatric disorders. Use may aggravate preexisting psychiatric conditions. Steroid-induced psychosis is dose-related, occurs within 15 to 30 days of therapy and is treatable if steroid therapy must be continued.
TizanidineFrom Wikipedia, the free encyclopediaRoutes Oral, Intranasal, Injection Tizanidine (brandnames Zanaflex, Sirdalud) is a drug which is used as a muscle relaxant. It is a centrally acting α-2 adrenergic agonist. It is used to treat the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, spastic diplegia, back pain, or certain other injuries to the spine or central nervous system. It is also prescribed off-label as a sleep aid, seizure inhibitor, and for some symptoms of fibromyalgia.
Some anticonvulsant drugs are effective in treating bipolar disorder, fibromyalgia...The anticonvulsants are also known as anti-epileptics. They were designed -- and are approved by the Food and Drug Administration -- primarily to treat people who have various kinds of seizure disorders, including seizures or convulsions caused by epilepsy, strokes, and brain tumors. Several -- phenytoin (Dilantin), carbamazepine (Carbatrol, Tegretol,), ethotoin (Peganone), and valproic acid/divalproex (Depakene/Depakote) -- have been on the market since the 1950s. But a "second generation" of anticonvulsants was developed in the 1990s. These include gabapentin (Neurontin), lamotrigine (Lamictal), pregabalin (Lyrica) and topiramate (Topamax).
Cognitive Behavioral Insomnia Therapy for Individuals With FibromyalgiaThis study is currently recruiting participants. Verified by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)The purpose of this study is to evaluate the effectiveness of cognitive behavioral insomnia therapy in reducing sleep disturbances and improving other FM-related symptoms.
It includes the BNF details medicines prescribed in the UK, with special reference to their uses, cautions, contraindications, side-effects, dosage and relative costs. Updated in print every six months, the BNF reflects current best practice as well as legal and professional guidelines relating to the use of medicines.
Have you had an epidural at any time?
Stay away from the pomegranate juice as it is a very powerful oestrogen loaded drink that will play havoc with your other problems.
IBT will give you the leverage to rapidly detox s it increases urine density markedly over flat bedrest and daily activity.
And with your psychology background you may be able to give an accurate description of changes, so please make a note of anything which we can reflect upon down the road to some significant recovery.
Thank you for your kind offer to monitor your varicose veins also as this will prove very useful in say 4 weeks from when you tilt your bed. I say bed because when the bed is tilted it will be far more beneficial than sleeping on the couch. The dogs will love it also If you could take discrete photographs of the veins you are monitoring so we can see a before and after it would prove very useful, if not don't worry about it.
the flash in this artificial light just burned the images out.
Helping the medical profession to better understand the nature of the condition, or similar, related conditions, the ups and downs, and effects on the daily life of someone with such, is an area that I may well be useful in.
In fact, and to be fair to anyone reading this, I am being urged to attempt to do this by a number of other people. It is possible some may, in their own time, come forward here and reveal themselves. That will be up to them, but I have suggested they do so and as a result of private email correspondence that I've received.One has mentioned the difference that one of the drugs that you mentioned has made to them, and we are exchanging an interesting dialogue, so even if there's not a great deal of feedback forthcoming, as yet, in this thread, some good is coming from it, which is encouraging.
Stay away from the pomegranate juice as it is a very powerful oestrogen loaded drink that will play havoc with your other problems
I have it in my head that I may be short of magnesium, although where that idea has come from I don't know
Thank you, Andrew!! I'll try that! (I suppose brewing for 10 minutes?)Anybody with any ideas re this?
LOL - When it comes to long posts, I can hardly point a finger at you, now can I, GOM? Andrew...I am going to print out a large print version of your post in a minute, and take my time going through it. My eye muscles are still tired after it's only been possible to get another four house sleep and from gone 6am until my helper's husband telephone to try and wake me in time for the district nurse's visit. (My helper was worried sick, as she failed to wake me at all when here from 8 - 10 am.) Phone penetrated as far as the reptilian brain (archipallium) and just about reached the paleomammallian level by the time I answered. (Powerless over the first thought, but not over the second!) Thankfully, the neomammalian rationale surfaced before the tongue lashed!Whatever, even through the p-holes in the snow, a LOT of things are leaping out at me from your post. Doing justice to any reply will take time - and probably a few more hours sleep, too. I am not fibro-fogged YET, but am not sufficiently alert to do justice to responding to your post at present - but I will be. No more muscle spasms to report yet, either, but there was 100ml of discharge in the drain when it was changes, but the district nurse (a fellow fibro sufferer) forgave me and understood why only too well when I explained what I'd done. Stuck with the drain for at least another two days, though. Small price to pay to be free of those spasms!Grumpy Old Mare...Thanks for coming out into to open here. Could it be that your challenge team's shaman's missing right arm is responsible for pulling your extra left leg? He is certainly helping to keep me awake with his mind games on the TRPD forum!For the benefit of others here, this is copied and pasted from my reply to the Grumpy Old Mare's PM to me about the possible hormone connection...Good point about the hormones, and possibly one worth you posting in that Naked Scientists thread, too. I have learned that, ref. the cancer, I am hormone receptive, therefore will be having the anti-hormone drug treatment in combination with chemo and probably radiotherapy. However, I had a hysterectomy in 1991, when they also removed my left ovary, leaving the right, which, apparently, now has cysts. Presumably unruptured egg follicles? That was left so that the hormones would help to delay any onset of osteoporosis. I mentioned this recently to the cancer specialist nurse and the doctor, and was told it probably wasn't working now anyway.[/b]Before I can take my replies further, I really do need to rest both my eyes and brain(s) now. I might even end up sleeping the clock around, which often happens after a really bad flare, so don't anyone worry if the old dragon appears to be in hibernation. She's just away with the dogs on the sofa... Yes, I know, barking mad. (A bit like the spell-check on here, it seems... clearly lacks education... How the heck IS 'unruptured' spelled, please? It sure as heck isn't an enraptured egg follicle in that condition!)Grumpy Old Mare - just realised that your team mate's gonna get another win as soon as I hit the 'Post' button... But I am too tired now to care let alone explain... 'Enraptured Egg Follicles Challenge' my aging... donkey! Let your extra leg explain that one.
"I have quite a complex medical history that includes spinal damage; fibromyalgia and recently diagnosed breast cancer - oh, and I need to lose around 4 stones to aid mobility but without that impacting on pending chemotherapy (following lumpectomy and full lymph node axillary clearance) and fibro associated IBS sensitivities."
A friend of mine is drinking it also in hopes she will receive some benefits... what kind of troubles specifically did you run into..