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Bullous pemphigoid is a blistering skin disease which usually affects middle aged or elderly persons. It is an immunobullous disease, i.e. the blisters are due an immune reaction within the skin. What does it look like?Characteristically, crops of tense, fluid-filled blisters develop. They may arise from normal-looking or red patches of skin, and the blisters may be filled with clear, cloudy or blood-stained fluid. Bullous pemphigoid is usually very itchy. It may be localized to one area but is more often widespread, often favouring body folds. In severe cases, there may be blisters over the entire skin surface as well as blisters inside the mouth.