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Sensodyne-F contains potassium nitrate 5% w/w, as the desensitizing agent, and also contains fluoride for ongoing caries prevention. Potassium nitrate inhibits repolarization of sensory nerve endings, thereby reducing the pain response to stimulation
Sensodyne Original formula contains strontium chloride 10% w/w. Strontium chloride occludes the dentinal tubules, thereby reducing fluid flow and dentin hypersensitivity pain. This formula does not contain fluoride.