Does aspirin interact with St. John's Wort?

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Morag Selkirk

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Does aspirin interact with St. John's Wort?
« on: 04/02/2009 00:30:01 »
Morag Selkirk  asked the Naked Scientists:

Can you tell me if there is any interaction between St John's Wort and aspirin?  Or does one cancel the other out?

With thanks
Morag Selkirk

What do you think?


Offline DrN

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Does aspirin interact with St. John's Wort?
« Reply #1 on: 14/02/2009 22:02:19 »
This was on RxList for St Johns Wort ('s+Wort+Oral.aspx?drugid=1773&drugname=St.+John's+Wort+Oral):

Aspirin can increase the risk of bleeding when used with this product. If your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Discuss the risks and benefits with your doctor.

Basically, it seems like there is probably no direct chemical interaction, but may cause harm when the two are taken together. Although, further up the page, it does list NSAIDs as being a group of drugs that may interact with St Johns Wort. They state ibuprofen, but aspirin also belongs to this group. It would be advisable to discuss any medication you take with a pharmacist or GP before taking St Johns Wort.