[moses lawn (OP)]

I am on pravastatin because of slightly elevated cholesterol, but I am suffering considerably from the muscle pain associated with this drug.

Is there any evidence that changing to another statin, say simvastatin, would reduce likelihood of the muscle pain side effect, or is this a true class effect, in which all members of the class are equally likely to carry this problem to the same extent?

"You play ball with me, and I'll scratch yours"

[Andrew K Fletcher]

A single dose of cholesterol lowering drug causes painful muscle

Croft Woodruff

Code: [Select]

http://www.newmediaexplorer.org/chris/2004/03/20/cholesterol_drug_muscle_pain.htm----------------------------------------------------------------------------------------------------------------------------


1: Heart. 2004 Jan;90(1):e3.

Rhabdomyolysis induced by a single dose of a statin.

Jamil S, Iqbal P.

Medical Directorate, Chesterfield and North Derbyshire Royal Hospital NHS Calow, Chesterfield, UK.

Statins have been shown to cause myotoxicity and rhabdomyolysis. In most cases rhabdomyolysis occurs following the use of these drugs for at least one week. A case of rhabdomyolysis after just a single dose of simvastatin is reported.

Publication Types:
Case Reports

PMID: 14676266 [PubMed - indexed for MEDLINE]

http://www.newmediaexplorer.org/chris/2003/11/07/bad_news_about_statin_drugs.htm

Andrew



"The explanation requiring the fewest assumptions is most likely to be correct."
K.I.S. "Keep it simple!"

[chris]

How long have you been taking the prava ?

"I never forget a face, but in your case I'll make an exception"
 - Groucho Marx