How can I turn my blood green?

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Offline ATremor

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How can I turn my blood green?
« on: 16/05/2010 02:33:18 »
On a 2007 podcast it was reported that a Vancouver man oooozed green blood. It was presumed that this had occurred because of the man taking a much higher dose of his migraine medication that contained Sumatriptan.  Sumatriptan contains a sulfur group that was binding to the hemoglobin in place of oxygen.  I currently take the same medication so I've often wondered how much I'd actually have to take to have this same effect. Don't think I'd care to be a test subject, but it'd be a hell of a party trick on St. Patricks Day!  Would this be a common phenomenon with overdoses containing this compound? Thanks

Adam

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Offline Bored chemist

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How can I turn my blood green?
« Reply #1 on: 16/05/2010 15:37:05 »
Sulfhemoglobin doesn't carry oxygen. You might want to think about the potential consequence of that.
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Offline ATremor

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How can I turn my blood green?
« Reply #2 on: 17/05/2010 00:23:28 »
Not all of the RBC's will be bound to sulfur. I think on the podcast it mentioned he had 1 gram of sumatriptan for every liter of blood and his was green.

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Offline chris

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How can I turn my blood green?
« Reply #3 on: 18/05/2010 12:45:50 »
Here's a link to the transcript of that news item from when it was covered:

http://www.thenakedscientists.com/HTML/content/news/news/745/

The original item was published in the Lancet:

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(07)60918-0/fulltext

Chris
« Last Edit: 18/05/2010 12:49:29 by chris »
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Offline ATremor

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How can I turn my blood green?
« Reply #4 on: 21/05/2010 22:54:43 »
Very cool case. Thanks for the links Chris!