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Physiology & Medicine
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05/01/2006 09:25:46 »
Thank you for a really great site it has been both interesting and helpful. I started out looking for a link between Type 2 Diabeties and Fungal infections. This led to several sites that claimed that the Probiotics were the answer to everything. One site in particular promoted THREELAC which is said to contain Bacillius Coagulans, Bacillus Subtillis and Enterococcus Faecalis. These bugs were not mentioned in your article on this. Also most commentators reviewing past studies seem to get caught up on the survivability of the bugs as they pass through the high acid environment which leads to conclusions that probiotics in general cannot be shown to be very effective.I have two questions, Are these bugs well known and beneficial, and is it possible to get them alive through to the lower gut where they might do some good. If the answer to these two questions is positive then do you know of any evidence that this approach could lead to improvements in the management of either Type2 Diabeties and/or fungal infections
Re: gut bugs
Reply #1 on:
05/01/2006 18:07:34 »
there is a method of delivering drugs to the intestine called "Modified Release (MR)" :
an "enteric coating" encapsulates the drug, this capsule only breaks open, releasing the medicine,
AFTER it has passed through the stomach. (I believe the stomach acid softens the coating, but does not rupture the capsule).
This method could be used to deliver probiotic bacteria to the intestine, protecting them from stomach acid.
Last Edit: 07/01/2006 11:13:39 by ROBERT
Neilep Level Member
The Naked Scientist
Re: gut bugs
Reply #2 on:
09/01/2006 11:38:34 »
a show from the 23rd January 2005 featured microbiologist and pro-biotic specialist Prof. Glenn Gibson from the University of Reading. He discussed this at some length and took a number of calls from listeners :
- Radio show about Probiotics and gut bacteria with Prof. Glenn Gibson
Also, Jemima Stockton has written a thorough
account of the applications and evidence for the effectiveness of probiotics
"I never forget a face, but in your case I'll make an exception"
- Groucho Marx
Last Edit: 09/01/2006 11:40:05 by chris
I never forget a face, but in your case I'll make an exception - Groucho Marx