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Matthew Hodge asked the Naked Scientists: Hi Chris, Dave, Kat and the rest of the Naked Scientist team,I love your programme! Great diversity in topics and very accessible level of discussion. My wife bought me a ipod for my birthday and then I discovered "THE NAKED SCIENTIST" I'm up to mid 2009 in your Podcast listing. I have a question you could slot into a show related to genetics.Question: What is the difference at the genetic level between to identical groups of animals, then evolving separately, that then prevents them producing fertile offspring?So by definition what prevents inter species breading? Fanciful Example 1: There is a island populated with a particular snake on it and an earthquake splits the island in two. Due to the extinction of some predators and plants on one island, the two snake groups evolve different colouration, size and venom. Then another freak earthquake joins the two islands, now both snakes would be benefit from a mix of colour size and venom. Why wouldn't the genes allow this re-blending?