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Mankind has managed to eradicate smallpox apart from two stocks of it kept in "secure" research lab stores, one in the US, one in the former USSR, I think it's in Russia.
Smallpox has no host apart from man, so once it's gone, it's gone. There's no scientific reason to keep it. We know the genome so, in principle, we could rebuild it if there were any need to (though I can't imagine why there might be). You don't need the virus to make a vaccine (you can use cowpox) and if we got rid of it there wouldn't be any call for the vaccine anyway.
If it were to escape (or be deliberately released) from those stores it would rip through the population. The lack of vaccination over the last decades would mean we would get a plague of biblical proportions.
Essentially all the data we have on the infectivity and mortality of smallpox is based on experience with populations which had already been exposed to it and/ or vaccinated.Today, very few people have any immunity, very few have been vaccinated and I rather doubt that there are stocks of the vaccine (why bother to clutter up the fridges with a vaccine for a disease that doesn't exist?)I rather suspect that an outbreak today would be a lot nastier than in the past, and it wasn't nice then.