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quote:Originally posted by cannabinoidConformational isomers are those that have the same chemical formula and same basic structure, but the molecules occupy different positions on that structure. For instance, picture 1-methyl-4-chloro-2-butene. The double bond is in the middle of the molecule, and the methyl and chloro groups can both be on the top/bottom of the double bond or on opposite sides. Respectively, they are called cis and trans conformations. Think of it as 2 identical houses, but on one there is a front door and side door on adjacent sides of the house and on the other, there is a front door and a back door on the opposite side of the house.