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We selected 86 molecules that span olfactory stimulus space and individually diluted them to a point of about equal intensity...
We obtained 86 monomolecular odorants that were well distributed in both perceptual (Fig. 1A) (1, 11–13) and physicochemical (Fig. 1B) (1, 14, 15) stimulus space.
In vision and audition, the clear mapping between physical and perceptual dimensions allowed identification of the physical limits of perception (390 to 750 nm in color vision and 20 Hz to 20 kHz in auditory pitch). Therefore, spanning physical space in these domains is relatively straightforward. In contrast, the full extent of olfactory physicochemical space remains unknown, and its key axes remain poorly defined.