Would you want to know what's lurking in your genome?

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Offline thedoc

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A genetic screen tells your doctor knows you are at increased risk of getting cancer.  You’d want to know, right?  Or maybe not? And what about those people with whom you share your genes, such as parents, bothers, sisters or children. You knowing affects them too. Anna Middleton has set up a survey to find out what we think about these issues...

Read the article then tell us what you think...
« Last Edit: 30/09/2016 16:52:34 by _system »


Offline CliffordK

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Re: Would you want to know what's lurking in your genome?
« Reply #1 on: 16/09/2013 20:29:09 »
Knowledge such as cancer risk may help with determining appropriate asymptomatic screening.  Perhaps it may also direct expensive tests when a patient has ambiguous symptoms.  Preventative treatments such as bilateral mastectomy?

There are a lot of issues with testing for genetic diseases such as Huntington's disease that present in middle-age adults.

Parents might choose to know risk factors for recessive diseases such as cystic fibrosis or sickle cell anemia which may also involve prenatal testing.


Offline chris

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Re: Would you want to know what's lurking in your genome?
« Reply #2 on: 17/09/2013 23:17:38 »
Absolutely. Huntington's is a condition that, currently, we can do almost nothing for. So if one sibling discovers they carry it, then there's a certainty that a parent does, and at least a 50% chance that a brother or sister also do. Neither may wish to know, since the only effect would be to affect quality of life. Although it might also affect decisions to have children I suppose.

In one family I know affected by this, in which the father died of HD about 10 years ago, there is a daughter. She has elected not to test herself and has gone on to have children.

Here we have an interesting situation, since those children will know their parentage and risk, and may want to test themselves; if they do they'll reveal Mum's genotype.
I never forget a face, but in your case I'll make an exception - Groucho Marx