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Among other things, it has been tested as a male oral contraceptive in China.
Quote from: http://en.wikipedia.org/wiki/GossypolAmong other things, it has been tested as a male oral contraceptive in China. [xx(] [xx(] [xx(]Here is a summary of two different methods of processing the cottonseed oil. The processing seems to rely on the Gossypol becoming water soluble in a basic solution. Then the oil is separated from the aqueous phase. It may also involve drying and evaporation.Thus, any chemical that had a relatively high boiling point, is heat stable, and is oil soluble may in fact be able to pass through the processing.