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all reactions have a degree of unpredictability, but decisions must be made..
a good reaction is one that replicates desireably, survival of the most aesthetically associated randomness
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Of course everything is subject to natural selection, including chemical reactions. The formation of heavier elements over time in the universe is not a new idea. Or, if you mean the conditions of the universe out of many possible states that is also not a new idea. What exactly did you have in mind anyway?