Post Orgasmic Illness Syndrome (POIS)

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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12850 on: 17/04/2011 01:24:41 »

Semen includes non-sperm liquids. Are you suggesting liquids that are NOT semen?

Perhaps you meant to write, "Maybe it's not only a semen sperm allergy but also an allergy for the other liquids after an ejaculation."
Yes this is what I mean:
"Maybe it's not only a semen sperm allergy but also an allergy for the other liquids after an ejaculation."

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12851 on: 17/04/2011 04:10:10 »

Demo T/P Update Day 5 - Final


POIS appears to be 99% symptom-free today, but I'm suspicious of the placebo effect.

Thank you everyone for "participating" with me in this 'adventure'. I probably wouldn't have attempted it without your support (and of course my wonderful endocrinologist's).

edit - discontinuing T/P, as explained earlier (side effects).
« Last Edit: 17/04/2011 07:03:16 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12852 on: 17/04/2011 04:21:35 »

Semen includes non-sperm liquids. Are you suggesting liquids that are NOT semen?

Perhaps you meant to write, "Maybe it's not only a semen sperm allergy but also an allergy for the other liquids after an ejaculation."


Yes this is what I mean:
"Maybe it's not only a semen sperm allergy but also an allergy for the other liquids after an ejaculation."


Van. thank you very much for clarifying.

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Offline Green

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12853 on: 17/04/2011 12:10:52 »
Just a quick update on my situation, today is day 1 of POIS, apart from bloating there is no brainfog or fatigue, just a groggy feeling and I can think pretty clearly, slight back pain and indegestion but, this has to be one of the least symptomatic POIS episodes I've ever had in my life.


I've been experimenting quite a bit, it appears if you tweak the dosages POIS can be almost emilnated, depending on sex/masturbation frequency.

I have been abstaining for a month and then ejaculating 2-3 in a week and repeat for a the past 4-5 months, each and every time the resulting POIS is becoming less and less, and only know I'm starting to feel the postive effects of Orgasm, mood is better, concentration is actually slightly up and stress levels seem to be reduced, all of which quantify POIS is reducing each and everytime, I'm very confident, in a year or so I'll be totally POIS free, given the massive milestone I've come about today.

For those of you who are on test/HCG, it might be worth trying my method and seeing if it works for you, also. It seems to be modulating my system to accept orgasm, who knows.
« Last Edit: 17/04/2011 12:12:48 by Green »

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Offline daveman

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12854 on: 17/04/2011 16:06:10 »
Just a quick update on my situation, today is day 1 of POIS, apart from bloating there is no brainfog or fatigue, just a groggy feeling and I can think pretty clearly, slight back pain and indegestion but, this has to be one of the least symptomatic POIS episodes I've ever had in my life.


I've been experimenting quite a bit, it appears if you tweak the dosages POIS can be almost emilnated, depending on sex/masturbation frequency.

I have been abstaining for a month and then ejaculating 2-3 in a week and repeat for a the past 4-5 months, each and every time the resulting POIS is becoming less and less, and only know I'm starting to feel the postive effects of Orgasm, mood is better, concentration is actually slightly up and stress levels seem to be reduced, all of which quantify POIS is reducing each and everytime, I'm very confident, in a year or so I'll be totally POIS free, given the massive milestone I've come about today.

For those of you who are on test/HCG, it might be worth trying my method and seeing if it works for you, also. It seems to be modulating my system to accept orgasm, who knows.

Just a reminder Green, you are on TRT? What is the dosage?

I wonder how this abstenance/2-3 per wk program could work for those who are not taking T as well?

Thx
How does Murphey do it??

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12855 on: 17/04/2011 20:14:35 »
Just a quick update on my situation, today is day 1 of POIS, apart from bloating there is no brainfog or fatigue, just a groggy feeling and I can think pretty clearly, slight back pain and indegestion but, this has to be one of the least symptomatic POIS episodes I've ever had in my life.


I've been experimenting quite a bit, it appears if you tweak the dosages POIS can be almost emilnated, depending on sex/masturbation frequency.

I have been abstaining for a month and then ejaculating 2-3 in a week and repeat for a the past 4-5 months, each and every time the resulting POIS is becoming less and less, and only know I'm starting to feel the postive effects of Orgasm, mood is better, concentration is actually slightly up and stress levels seem to be reduced, all of which quantify POIS is reducing each and everytime, I'm very confident, in a year or so I'll be totally POIS free, given the massive milestone I've come about today.

For those of you who are on test/HCG, it might be worth trying my method and seeing if it works for you, also. It seems to be modulating my system to accept orgasm, who knows.

Fantastic news, Green, thank you for sharing it!!!

Would you mind re-capping your med-mix?
« Last Edit: 17/04/2011 20:21:59 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12856 on: 17/04/2011 20:29:07 »

I wonder how [Green's] abstinence/2-3 per wk program could work for those who are not taking T as well?


Yes, I am curious, too! I have likewise had success with abstinence/continuation but it was fuzzy/accidental and nowhere near Green's length-of-abstention as well as precise measurement, so I'm anxious to learn more.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12857 on: 17/04/2011 20:45:20 »

Demo T/P Update Day 5 - Final

POIS appears to be 99% symptom-free today, but I'm suspicious of the placebo effect.

Thank you everyone for "participating" with me in this 'adventure'. I probably wouldn't have attempted it without your support (and of course my wonderful endocrinologist's).

edit - discontinuing T/P, as explained earlier (side effects).


Just to clarify for anyone following this, I stopped the 'P' in T/P before Day 5. So...my total T/P experimentation lasted 4 days, but I reported on the 5th Day because I assumed the 'P' was still in my system due to the half-life of most medications that I'm aware of. Thanks again.

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Offline daveman

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12858 on: 17/04/2011 22:10:54 »
Demo,

Do you still have the Rx, in case you might somehow decide to try the "P" again?

How does Murphey do it??

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12859 on: 17/04/2011 22:39:17 »

Demo,

Do you still have the Rx, in case you might somehow decide to try the "P" again?



Yes, Dave, including 4X refills! Pssst, wanna buy some...whoops, nevermind that's illegal! [;D]
« Last Edit: 17/04/2011 22:43:05 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12860 on: 17/04/2011 22:47:07 »
Joking aside, I have thought of re-starting. But bothersome that I didn't adjust even after 4 (daily) doses. Took nausea meds even last night, 36+ hours since last dose. Today I'm ok.

I'm waiting for Guinea Pig #2  [;D]
« Last Edit: 17/04/2011 22:49:21 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12861 on: 17/04/2011 22:52:48 »

Re-reading Dr Dexter's POIS paper was REALLY interesting! Now I see why my endo said to go ahead even after Zero-Sperm-Count. Dexter's case study made an impression on my endo (and he is a VERY skeptical endo).

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Offline dbfd588

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12862 on: 18/04/2011 04:38:33 »
abstinence dont fix nothin! Ive abstained for the last 3 or so years. Im 21 and its been hard but POIS sucks! So its been worth it. Only orgasms I have are thru NE's about ever 2-3 weeks and POIS is still pretty strong. Usually a 2 day session. My symstoms have kinda contained to headache, tight chest, indigestion, and just lousy POIS feeling. Ive have tried the Fenugreek and it does seem to help take the edge off of the symtoms. But as far as abstinence goes, for me it helps because of the less frequent POIS, but it doesnt seem to help as far as the serverity of the symptoms I have. Well maybe tt has because I remmeber a time when POIS lasted a week. Symptoms as strong but last a shorter time.

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Offline Counterpoints

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12863 on: 18/04/2011 18:41:08 »
Tamsulosin update

For those who don't remember, Tamsulosin (aka Flomax) is a selective alpha-1A blocker, like Silodosin.  I took tamsulosin and it prevented semen from being emitted from the urethra upon orgasm; in other words, it gave me dry orgasms.  I did still have muscular contractions, and I may have had retrograde ejaculation, although I did not notice anything unusual in my urine.

In my last update, I said that on Tamsulosin I noticed a difference in my symptoms.  I will now be more specific about this.  The symptoms were generally worse following ejaculation, and there were qualitative changes.  For instance, I consistently got heart palpitations, and difficulty focusing and communicating, in addition to this great need for relief in two different ways which can be described with two different analogies -- 1) as if I had to go pee and was somehow unable to empty my bladder, 2) as if I had a drug addiction (e.g. heroin) and took flour instead.

Also, while on Tamsulosin, I instinctively felt I could not alleviate my symptoms with subsequent orgasm, as I have often been able to do.  It seemed, generally, that every time I had (a tamsulosin) orgasm my symptoms got worse.

Overall Tamsulosin made things worse rather than better, but to be fair I only tried it for a period of about 2 weeks.

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Offline Animus

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12864 on: 18/04/2011 19:39:07 »
Tamsulosin update


Counterpoints,
I know what you mean by the great need for relief analogies I think. I felt the same way when I took medications that I interacted badly with, it was hard to describe literally. But I felt the exact same way.
It sounds like you had a bad interaction with it...

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Offline Counterpoints

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12865 on: 18/04/2011 19:51:46 »
Tamsulosin update


Counterpoints,
I know what you mean by the great need for relief analogies I think. I felt the same way when I took medications that I interacted badly with, it was hard to describe literally. But I felt the exact same way.
It sounds like you had a bad interaction with it...


I didn't really have side effects from the drug (without orgasm I felt normal), it just affected the way I responded to orgasm.  It also made some symptoms I occasionally have after orgasm (like heart palpitations) very consistent.

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Offline Habibou

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12866 on: 18/04/2011 21:26:07 »
Hi,I'M 51 and I'm suffering of this disease since 12 years. I saw many doctors. Today i talked to one of them who met Dr Marcel Waldinger at Malaga on this November. Dr Waldinger said to my doctor that he found the problem that cause POIS. However, Dr Waldinger don't want to talk right now. He's negotiating whit a scientific publication to publish is work. He told to my doctor that it would be published by 2 or 3 months from now. They met at a congress in Malaga this November.

Please, do you know more about this conference? :)  Smiley my doctors asked me some details , thank you !

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Offline daveman

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12867 on: 18/04/2011 21:41:08 »
Tamsulosin update


Counterpoints,
I know what you mean by the great need for relief analogies I think. I felt the same way when I took medications that I interacted badly with, it was hard to describe literally. But I felt the exact same way.
It sounds like you had a bad interaction with it...


I didn't really have side effects from the drug (without orgasm I felt normal), it just affected the way I responded to orgasm.  It also made some symptoms I occasionally have after orgasm (like heart palpitations) very consistent.

The only note I might make, is that when I feel I have had retrograde ejaculation, things are worse for me in the same way as you mention but without the effects of "withdrawl" or desperately needeing to be fulfilled.
« Last Edit: 18/04/2011 23:03:57 by daveman »
How does Murphey do it??

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12868 on: 18/04/2011 22:12:19 »

Hi,I'M 51 and I'm suffering of this disease since 12 years. I saw many doctors. Today i talked to one of them who met Dr Marcel Waldinger at Malaga on this November. Dr Waldinger said to my doctor that he found the problem that cause POIS. However, Dr Waldinger don't want to talk right now. He's negotiating whit a scientific publication to publish is work. He told to my doctor that it would be published by 2 or 3 months from now. They met at a congress in Malaga this November.


Please, do you know more about this conference? :)  Smiley my doctors asked me some details , thank you !


It was the 13th Congress of The European Society For Sexual Medicine, November 14-17, 2010, Malaga Spain:
http://www.essm.org/fileadmin/user_upload/medien/download/pdf/Programms/ESSM_Final_Program.pdf

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12869 on: 18/04/2011 22:17:21 »

Tamsulosin update


I took it for quite some time for its intended use, never saw any POIS effect. Didn't work particularly well for its intended use either.
« Last Edit: 18/04/2011 22:51:20 by demografx »

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Offline Counterpoints

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12870 on: 18/04/2011 23:15:29 »

Tamsulosin update


I took it for quite some time for its intended use, never saw any POIS effect. Didn't work particularly well for its intended use either.

Did it cause orgasms to be dry? (no ejaculation from urethra?)

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Offline apostate801

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12871 on: 19/04/2011 01:24:53 »
Whoever mentioned saw palmetto helping their symptoms, thanks!  Been taking it for a month and having sex about once a week, noticed a decrease in symptoms.  It's still there but definitely more tolerable and not as long lasting?  I want to test more sex but too scared.  Full on POIS is brutal.

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12872 on: 19/04/2011 07:33:32 »
I took [Flomax] for quite some time for its intended use, never saw any POIS effect. Didn't work particularly well for its intended use either.
Did it cause orgasms to be dry? (no ejaculation from urethra?)
No.
« Last Edit: 19/04/2011 07:51:05 by demografx »

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12873 on: 19/04/2011 07:34:19 »

Full on POIS is brutal.


"Truer words were never spoken"!


« Last Edit: 19/04/2011 07:52:05 by demografx »

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Offline alky

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12874 on: 19/04/2011 16:33:22 »
Whoever mentioned saw palmetto helping their symptoms, thanks!  Been taking it for a month and having sex about once a week, noticed a decrease in symptoms.  It's still there but definitely more tolerable and not as long lasting?  I want to test more sex but too scared.  Full on POIS is brutal.


Hello good to hear that. i think i want to try one of these natural herbs but what should i chose for the first time? 

saw palmetto or fenugreek ? thanks guys . From what i can see saw palmetto is much more expensive than fenugreek.
« Last Edit: 19/04/2011 16:57:22 by alky »

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Offline alky

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12875 on: 19/04/2011 16:47:11 »


edit - sorry if my initial reaction came across harshly, see follow up posts.

no problem

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Offline Willem

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12876 on: 19/04/2011 18:08:49 »
Hey guys, new to this forum.  Been a POIS sufferer for 7 years, 32 years old.  Thanks for all the info. 
My symptoms:
POIS seems to affect my muscles and nerves the most.  Right after orgasm whatever muscles I've been using at the time start to ache.  POIS lasts for about 1 week and during that time my body can't seem to repair muscle or nerve damage so I get repetitive motion injuries and can't lift weights.  Mild brain fog (though I'm loathe to admit it). 

Treatments I've tried that worked:
1) For over 1 year MgCl worked very well.  Didn't stop my reaction, but seemed to help my muscles and nerves recover faster.  Can't take it any more as it upsets my stomach and is no longer effective. 
2) Currently on Claritin after reading the Jan publications on POIS.  It's working the best of any treatment I've tried.  Still feeling fatigue, but seeing about 80% improvement in muscles and nerves.

Tests:
Was tested by an allergist doing subcutaneaous injection at (I believe) 1/100 and 1/1000 dilutions using my wife as a control.  I tested negative for the skin reaction (same as my wife), but had the same immediate muscle aches, which leads me to believe that it is an allergy. 

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Offline Willem

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12877 on: 19/04/2011 18:11:28 »
Because of my negative reaction on the allergy test, the allergist doesn't think a subcutaneous immunotherapy makes sense.  I'm tempted to do my own home dilution and sublingual immunotherapy.  Has anyone out there attempted this? I apologize I haven't read through all the posts.

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Offline Willem

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12878 on: 19/04/2011 18:37:16 »
Thanks B_Jim.

Looks like it's very popular in Europe, but not so much in the U.S. After reading Dr. Waldinger's (et al) paper on Hyposensitization Therapy with Autologous Semen, I found this Wikipedia article on it:
http://en.wikipedia.org/wiki/Sublingual_immunotherapy

Not as effective as subcutaneous, but for a single known allergy it seems to work well, and might be an option for those of us who can't find an allergist willing to do a subcutaneous treatment.   

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Offline Willem

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12879 on: 19/04/2011 19:47:35 »
Is it effective ?
http://www.medscape.com/viewarticle/446202_4
'efficacy','possible efficacy','no efficacy'...
Thanks for the link B_Jim.  Even if it is effective, it would seem difficult to optimize the dosage and time span of treatment.  If it worked for POIS it might be years before a specific treatment plan could be recommended.
« Last Edit: 19/04/2011 19:51:46 by Willem »

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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12880 on: 19/04/2011 19:51:46 »
Is it effective ?
http://www.medscape.com/viewarticle/446202_4
'efficacy','possible efficacy','no efficacy'...
Thanks for the link B_Jim.  Even if it is effective, it would seem difficult to optimize the dosage and time span of treatment. 

welcome williem
when i did my test my semen was not diluted and i reacted, i was thinking maybe if yours is not diluted may be you will get immedieate reaction.

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Offline daveman

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12881 on: 19/04/2011 20:28:14 »
Hey guys, new to this forum.  Been a POIS sufferer for 7 years, 32 years old.  Thanks for all the info. 
My symptoms:
POIS seems to affect my muscles and nerves the most.  Right after orgasm whatever muscles I've been using at the time start to ache.  POIS lasts for about 1 week and during that time my body can't seem to repair muscle or nerve damage so I get repetitive motion injuries and can't lift weights.  Mild brain fog (though I'm loathe to admit it). 

Treatments I've tried that worked:
1) For over 1 year MgCl worked very well.  Didn't stop my reaction, but seemed to help my muscles and nerves recover faster.  Can't take it any more as it upsets my stomach and is no longer effective. 
2) Currently on Claritin after reading the Jan publications on POIS.  It's working the best of any treatment I've tried.  Still feeling fatigue, but seeing about 80% improvement in muscles and nerves.

Tests:
Was tested by an allergist doing subcutaneaous injection at (I believe) 1/100 and 1/1000 dilutions using my wife as a control.  I tested negative for the skin reaction (same as my wife), but had the same immediate muscle aches, which leads me to believe that it is an allergy. 

These nerve and muscle symptoms parallel mine very well. Lately, very simple things like operating a wrench on a simple plumbing coupling or lifting my nephew once or twice so he can "fly" produces a sensation of muscle damage for several days. Not just stiff, but as though there were damage to the tissues. In several days it goes away though.

Also, when I lifted weights (25 yrs ago), I had injuries in the inner elbows, where the muscle attaches to the bone, when I did some weight excersizes. These come back now with POIS and last up to 2 wks. Similar pains at other union points (muscle to bone).

« Last Edit: 19/04/2011 20:54:05 by daveman »
How does Murphey do it??

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12882 on: 19/04/2011 21:56:18 »

Willem, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS resources which may be helpful to you:

The Learning Channel (TLC) upcoming feature TV presentation on POIS, featuring our member here at this forum, "Animus". They're planning to air it on May 22, 10pm Eastern Standard time. Animus will keep us informed of any changes.

Our POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

The POIS Information Website is home to the famous POIS Forum Compendium, written by "Pyropeach", and contains theories already discussed here and treatments that have both worked and failed.

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:
http://www.youtube.com/watch?v=UWBxAUC9k1g

Our new POIS chatroom (realtime chat). Invite or visit another member(s) there, ANY TIME. We can all get to know each other better:
http://forums.delphiforums.com/POIS/chat


* Most recent POIS Research Studies, 2011 *

If you will send Prof. dr. Waldinger an e-mail, stating that you have read his message on the Forum, at http://www.thenakedscientists.com/forum/index.php?topic=6576.msg340138#msg340138 and that you are willing to fill in a questionnaire, he will send you the copies of both 2011 research articles by return through email. At a later date, he will send you the questionnaire which, after having filled in, you should send him back by e-mail.
His email:
prof.dr.waldinger.pois@gmail.com

Prof. dr. Marcel D. Waldinger's website:
http://www.post-orgasmic-illness-syndrome.com/en/index.html


First POIS Research Study, 2002

We have a copy of the first formal medical investigation on POIS by Prof. dr. Marcel D. Waldinger,MD,PhD, and Dr. Dave Schweitzer, MD.

  
Recent POIS Research Study, 2010

CASE REPORT
Postorgasm Illness Syndrome - A Spectrum of Illnesses
Jane Ashby, MRCP, and David Goldmeier, MRCP
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg316781#msg316781


British Medical Journal Case Report, 2010

Case study by Dr. Selwyn Dexter of a patient with a headache-featured POIS symptom treated with progesterone/norethisterone.
http://casereports.bmj.com/content/2010/bcr.10.2009.2359.short?rss=1


There are a couple of ways to get any or all of the above 3 studies: (1) if you want a PDF copy, send me a Private Message (PM) with your regular email address (use "AT" instead of "@" ) and I'll send you back the PDF.

Or, if you prefer, (2) I can simply reply with a Private Message (no regular email needed) and provide you with a simple text version embedded in your PM.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

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In addition to serving our own informational interests, the resources listed above can be useful for you to show our credibility to the medical world - which often shows little understanding and is sometimes skeptical of our condition: POIS has scientific underpinnings and POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapeutic community. All of this information can greatly help you to fight the immediate reaction of some doctors: so just tell them, "IT'S NOT 'ALL IN OUR HEADS'! "

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum, which has already been referenced in respectable sources such as the Journal of Sexual Medicine (Dr. Waldinger's study), British Medical Journal and wikipedia:
http://en.wikipedia.org/wiki/Postorgasmic_illness_syndrome

For over 4 years, our POIS forum has attracted over 200 POIS sufferers worldwide who have posted here, research on an additional 200 sufferers elsewhere on the internet, plus over 1,000,000 page visits. Not bad for a rare malady!





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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12883 on: 19/04/2011 21:58:13 »


Willem, this post will help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:


SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: more than 4 years' worth of posts (over  10,000 posts!) from 200+ Forum members, and an additional 200 POIS sufferers found elsewhere on the Internet by Member B_Jim.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://thenakedscientists.com/

for example, I tried
nocturnal emission POIS site:http://thenakedscientists.com/

and 740 results came up for "nocturnal emission" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.



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Offline Willem

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12884 on: 19/04/2011 22:12:12 »
@demografx 
Thank you very much for the research synopsis and google search tips.  I purchased copies of the articles by Dr. Waldinger, but wasn't aware of the hormone research.  Thanks again.

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Offline Willem

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12885 on: 19/04/2011 22:15:48 »
Is it effective ?
http://www.medscape.com/viewarticle/446202_4
'efficacy','possible efficacy','no efficacy'...
Thanks for the link B_Jim.  Even if it is effective, it would seem difficult to optimize the dosage and time span of treatment.  If it worked for POIS it might be years before a specific treatment plan could be recommended.

It would be boring to lose 1 or 2 years more. :)

I think more and more to do the dilution and injection myself. Saline solution and syringes are available in pharmacy. Type I diabete sufferers do their own insuline injections. 
The dilution is the difficult point. But if CCC made a test with not diluted semen, maybe there is few risk for a lot of us (if not extreme flu-like symptoms case).

I agree with you.  My worry is that semen quickly coagulates in water (don't know about saline solution), and it might be difficult to get a uniform dilution. 

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Offline Willem

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12886 on: 19/04/2011 22:20:47 »
Hey guys, new to this forum.  Been a POIS sufferer for 7 years, 32 years old.  Thanks for all the info. 
My symptoms:
POIS seems to affect my muscles and nerves the most.  Right after orgasm whatever muscles I've been using at the time start to ache.  POIS lasts for about 1 week and during that time my body can't seem to repair muscle or nerve damage so I get repetitive motion injuries and can't lift weights.  Mild brain fog (though I'm loathe to admit it). 

Treatments I've tried that worked:
1) For over 1 year MgCl worked very well.  Didn't stop my reaction, but seemed to help my muscles and nerves recover faster.  Can't take it any more as it upsets my stomach and is no longer effective. 
2) Currently on Claritin after reading the Jan publications on POIS.  It's working the best of any treatment I've tried.  Still feeling fatigue, but seeing about 80% improvement in muscles and nerves.

Tests:
Was tested by an allergist doing subcutaneaous injection at (I believe) 1/100 and 1/1000 dilutions using my wife as a control.  I tested negative for the skin reaction (same as my wife), but had the same immediate muscle aches, which leads me to believe that it is an allergy. 

These nerve and muscle symptoms parallel mine very well. Lately, very simple things like operating a wrench on a simple plumbing coupling or lifting my nephew once or twice so he can "fly" produces a sensation of muscle damage for several days. Not just stiff, but as though there were damage to the tissues. In several days it goes away though.

Also, when I lifted weights (25 yrs ago), I had injuries in the inner elbows, where the muscle attaches to the bone, when I did some weight excersizes. These come back now with POIS and last up to 2 wks. Similar pains at other union points (muscle to bone).


I'm very sorry to hear that daveman, I wouldn't wish it upon anyone.  It's tough trying to explain to my boss that my leg muscles are sore for 2 months after wakeboarding so I can't go any more.  Looks at me like I'm some weirdo.

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Offline Willem

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12887 on: 19/04/2011 22:29:08 »
Hi all.
With all this no sperm talk with people with pois im
really worried about my future chances of having children.
Can anyone ease my fear about this?
Hey scooby, also wanted to chime in that I've had POIS for 7 years, but thankfully I've had no fertility issues.  Probably takes my wife and me an extra couple of months due to lower frequency, but that's nothing.  Have three boys ages 5, 3, and 1. 

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12888 on: 19/04/2011 22:39:33 »

@demografx 
Thank you very much for the research synopsis and google search tips.  I purchased copies of the articles by Dr. Waldinger, but wasn't aware of the hormone research.  Thanks again.


There are also additional studies/papers available that go into more detail regarding testosterone + progesterone (T/P), also known as 'Male Contraceptive Approaches'. If after reading Dr Dexter's case report on progesterone as a standalone remedy, and it is found interesting, anyone can PM me for those additional papers ( obtained by daveman, CCconfucius and myself). Did I leave any contributor out?

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12889 on: 19/04/2011 22:42:47 »
Hi all.
With all this no sperm talk with people with pois im
really worried about my future chances of having children.
Can anyone ease my fear about this?
Hey scooby, also wanted to chime in that I've had POIS for 7 years, but thankfully I've had no fertility issues.  Probably takes my wife and me an extra couple of months due to lower frequency, but that's nothing.  Have three boys ages 5, 3, and 1. 

Worth repeating! Many thanks for affirming  Willem, that there most certainly  _IS_  "Life After POIS !!"

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Offline emi_b

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12890 on: 20/04/2011 10:29:06 »
Hi, everybody.

I am a 20 years old male from Romania, who suffer from similar symptoms from when I was 17.

I have cognitive, psychological and physical symptoms, and they are very debilitating, and some of them are long lasting. I never found a true relief from then. I have posted a comprehensive history about my condition on the POIS forum.
I tried to copy that post here but there was an error.

I want to thank all of you for maintaining the POIS sufferers informed with the latest news, and to thank for spreading out info about this illness.

emi_b

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12891 on: 20/04/2011 19:07:49 »
Hi, everybody.

I am a 20 years old male from Romania, who suffer from similar symptoms from when I was 17.

I have cognitive, psychological and physical symptoms, and they are very debilitating, and some of them are long lasting. I never found a true relief from then. I have posted a comprehensive history about my condition on the POIS forum.
I tried to copy that post here but there was an error.

I want to thank all of you for maintaining the POIS sufferers informed with the latest news, and to thank for spreading out info about this illness.

emi_b


emi_b, thank you very much for your very kind words. Your presence and support here is also vital to us in our quest to find a cure!

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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12892 on: 20/04/2011 19:34:31 »


emi_b, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS resources which may be helpful to you:

The Learning Channel (TLC) upcoming feature TV presentation on POIS, featuring our member here at this forum, "Animus". They're planning to air it on May 22, 10pm Eastern Standard time. Animus will keep us informed of any changes.

Our POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

The POIS Information Website is home to the famous POIS Forum Compendium, written by "Pyropeach", and contains theories already discussed here and treatments that have both worked and failed.

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:
http://www.youtube.com/watch?v=UWBxAUC9k1g

Our new POIS chatroom (realtime chat). Invite or visit another member(s) there, ANY TIME. We can all get to know each other better:
http://forums.delphiforums.com/POIS/chat


* Most recent POIS Research Studies, 2011 *

If you will send Prof. dr. Waldinger an e-mail, stating that you have read his message on the Forum, at http://www.thenakedscientists.com/forum/index.php?topic=6576.msg340138#msg340138 and that you are willing to fill in a questionnaire, he will send you the copies of both 2011 research articles by return through email. At a later date, he will send you the questionnaire which, after having filled in, you should send him back by e-mail.
His email:
prof.dr.waldinger.pois@gmail.com

Prof. dr. Marcel D. Waldinger's website:
http://www.post-orgasmic-illness-syndrome.com/en/index.html


First POIS Research Study, 2002

We have a copy of the first formal medical investigation on POIS by Prof. dr. Marcel D. Waldinger,MD,PhD, and Dr. Dave Schweitzer, MD.

  
Recent POIS Research Study, 2010

CASE REPORT
Postorgasm Illness Syndrome - A Spectrum of Illnesses
Jane Ashby, MRCP, and David Goldmeier, MRCP
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg316781#msg316781


British Medical Journal Case Report, 2010

Case study by Dr. Selwyn Dexter of a patient with a headache-featured POIS symptom treated with progesterone/norethisterone.
http://casereports.bmj.com/content/2010/bcr.10.2009.2359.short?rss=1


There are a couple of ways to get any or all of the above 3 studies: (1) if you want a PDF copy, send me a Private Message (PM) with your regular email address (use "AT" instead of "@" ) and I'll send you back the PDF.

Or, if you prefer, (2) I can simply reply with a Private Message (no regular email needed) and provide you with a simple text version embedded in your PM.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show our credibility to the medical world - which often shows little understanding and is sometimes skeptical of our condition: POIS has scientific underpinnings and POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapeutic community. All of this information can greatly help you to fight the immediate reaction of some doctors: so just tell them, "IT'S NOT 'ALL IN OUR HEADS'! "

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum, which has already been referenced in respectable sources such as the Journal of Sexual Medicine (Dr. Waldinger's study), British Medical Journal and wikipedia:
http://en.wikipedia.org/wiki/Postorgasmic_illness_syndrome

For over 4 years, our POIS forum has attracted over 200 POIS sufferers worldwide who have posted here, research on an additional 200 sufferers elsewhere on the internet, plus over 1,000,000 page visits. Not bad for a rare malady!






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Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12893 on: 20/04/2011 19:36:37 »



emi_b, this post will help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:


SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: more than 4 years' worth of posts (over  10,000 posts!) from 200+ Forum members, and an additional 200 POIS sufferers found elsewhere on the Internet by Member B_Jim.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://thenakedscientists.com/

for example, I tried
nocturnal emission POIS site:http://thenakedscientists.com/

and 740 results came up for "nocturnal emission" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.




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Offline Nightingale

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12894 on: 20/04/2011 19:48:16 »
Hi again guys,

I'm trying to find the link to the page where all the sympathetic physicians/contacts are.  I found it on that new forum/website someone here had created, but I can't seem to find it now.  It's the one that has an IP address as part of the url

?

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Offline daveman

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12895 on: 20/04/2011 20:17:49 »
Nightingale,

You're looking for:

http://72.52.181.21/collaborator_list.php
How does Murphey do it??

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Offline Kingkong

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12896 on: 21/04/2011 23:50:53 »
Hi, I saw my doctor today. He read partly the result of the doctor Waldinger's reseach. He found the conclusion very interesting. He thinks that the idea that it would be an allergic reaction is probably the right cause. He had my father and my mother as a patient. Both of them had an immunologic desease. I'm doing asthma, i'm allrergic to any king of smoke. I'm allergic also to some chemical that they put in clothes. He suggest to me to try 10 mg of prednisone 6 hours before intercourse. He thinks that it must be an inflamation somewhere. To have an alergy, the semen have to reach the blood. An inflamation is a door for the semen to get into the blood. Is there some of you is taking prednisone or something like that? Thank you.

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Offline Defsync

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12897 on: 22/04/2011 01:04:47 »
Hey folks.

Apparently there is 2nd generation antihistamines now?

http://en.wikipedia.org/wiki/Loratadine

http://en.wikipedia.org/wiki/Cetirizine

Lots of detailed information at bluelight.

http://www.bluelight.ru/vb/showthread.php?t=400201

There is mention at bluelight they ahve more affect on the peripheral histamine receptors and not the CNS receptors, which could be key if histamine plays a roll in POIS.

I have had a couple O's with my girl, and have been on 200mg of Zoloft daily. I also have prescribed Imitrex (http://en.wikipedia.org/wiki/Sumatriptan) a migraine medication.

THe fatigue and mental deficiencies from POIS have been noticeably dulled the days after an O when I take and Imitrex.

Food for thought.

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Offline carlitto

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12898 on: 22/04/2011 09:09:18 »
Because of my negative reaction on the allergy test, the allergist doesn't think a subcutaneous immunotherapy makes sense.  I'm tempted to do my own home dilution and sublingual immunotherapy.  Has anyone out there attempted this? I apologize I haven't read through all the posts.

Interesting but weird! I had a pricktest AND a subcutaneous test just a month ago. The pricktest was negative whereas the intracutaneous injections were all positive. The 1:100 dilution gave a wheal as big as the histamine control and the doctor couldn't believe his eyes but dismissed the possibility of doing hyposensitization because he doesn't know if autologous semen injections always cause allergy-like wheals in ANY person. We had so to say no POIS-free 'control person' to compare with. I saw my doctor yesterday again and she said well your blood and semen values are all normal... I will prescribe pollen-allergy pills that generally suppress the immune system. Try them if you think it is allergy what you're suffering from, won't hurt to try.

I am really counting on Vandemolen to tell us hopefully in a couple of months if he is seeing any improvement as a result of his hyposensitization.

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Offline Vandemolen3

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #12899 on: 22/04/2011 09:49:12 »
Hi, I saw my doctor today. He read partly the result of the doctor Waldinger's reseach. He found the conclusion very interesting. He thinks that the idea that it would be an allergic reaction is probably the right cause. He had my father and my mother as a patient. Both of them had an immunologic desease. I'm doing asthma, i'm allrergic to any king of smoke. I'm allergic also to some chemical that they put in clothes. He suggest to me to try 10 mg of prednisone 6 hours before intercourse. He thinks that it must be an inflamation somewhere. To have an alergy, the semen have to reach the blood. An inflamation is a door for the semen to get into the blood. Is there some of you is taking prednisone or something like that? Thank you.
Prednisone is worth trying. Dr. Waldinger tried it with a few patients but it didn't work. But you never know. Remind that Prednisone is a very heavy medicine with a lot of side effects. And you can't just stop with it. Good luck!