Post Orgasmic Illness Syndrome (POIS)

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Offline horizon

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« Reply #14100 on: 21/07/2011 20:24:27 »
Since eating garlic all the time in POIS helps POIS but is completely impractical due to the death breath, I have been researching Garlic Injections.

I found this info..
http://www.webtrek.com/pipermail/sumo/2006-January/002317.html
http://yakyubaka.com/tag/garlic-injection/
http://curezone.com/forums/fm.asp?i=949656#i

> Does someone know what these garlic injections are ?
> What are they supposed
> to do ? When can you take it ?

Actually you can get a "garlic" injection at medical
clinics in Japan but "garlic" is a misnomer.  It isn't
as if they liquify garlic and shoot it in your vein.

Basically it refers to a certain injection made up
with a variety of vitamins but mostly B compounds.  As
you know vitamin Bs are known to help get you recover
quickly when you feel you are exhausted (especially
Vitamin B1 is known to break down lactic acids in your
body and as most athletes know accumulation of lactic
acids slow them down physically).  I've been told by
those who had the injection that they did feel they
were getting warmer and even smelled "garlicky" in
their mouth (I wonder if some amount of garlic is
actually in it...)

Other than Vitamin Bs I don't know whatelse in these
but remember when you are in a pharmacy or even kiosks
at train stations, you must have seen quite a few
"energy" drinks sold there.  These are basically all
drinks with vitamin Bs and some caffein to get you
revitalized back again quickly or so they tell me.
Actually many in Japan cannot do without them  and
some do swear by them (my wife actually gets a stock
of her "alpha mini" bottles whenever she goes to Japan).

« Last Edit: 21/07/2011 20:28:55 by horizon »

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Offline silverandcol

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« Reply #14101 on: 21/07/2011 22:43:47 »
Ok for my xan-pro report, I messed up a little bit but it is okay.  So I orgasm-ed  first and then took the xan-pro pills right after it.  Then I had to work next day so I went to sleep in like 15 minutes even with the slight flushing coming on.  I didn't notice anything else because I was sleeping.  Next day was kinda sucky, I would say 85% POIS.  I fucked up a bit a work because of my inattentiveness and whatnot from POIS, making me regret I ever ejaculated at all.  Good thing my boss is cool.  So when I got home I decdided to go all the way and text the Xan-Pro properly.  Took one 150mg  xanthinol nicotate+42mg Niacin pill tablet of Xan-Pro.  I waited about 30ish minutes then did my business.  It was pretty interesting. It seemed the orgasm was less intense(maybe because it's the 2nd day of orgasm.)  Also I did not get the super strong rush of blood to my face when I usually orgasm.  It definitely felt like a different orgasm. 

Next morning I was able to get up at 3:30am even before my alarm went off.  I was not lethargy stricken and being nearly impossible to get out of bed.  It was quite a good feeling of not being 100% POIS smashed.  Throughout the day at work I felt a little POIS, not sure if placebo though.  I would say about 50% POIS, not fully 100% sharp.  It's sometimes hard to tell at work because if it does not stress me out or challenge me enough I can't tell how much POIS I have.  I will play some games real soon though to see how the POIS is really effecting me.

TLDR: Xan-Pro is looking decently effective at reducing POIS symptoms when taken before orgasm.  (maybe the after helped too, I need to properly test this.) =D

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Offline victor.kons

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« Reply #14102 on: 22/07/2011 03:27:11 »
Hi horizon,

Since eating garlic all the time in POIS helps POIS but is completely impractical due to the death breath, I have been researching Garlic Injections.
After taking garlic you could eat a bit of fennel or parsley or try some other salad-grass, it should cancel death breath completely.

Victor

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Offline horizon

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« Reply #14103 on: 22/07/2011 07:16:00 »
Nah, you need to eat alot of Garlic to effect POIS well or take many smelly pills.
Its completely impractical to do this in the real world because of the horrendous smell.

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Offline demografx

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« Reply #14104 on: 22/07/2011 14:05:33 »

XN Tablets Report.

...I have unhealthy feeling at the location of liver...


I'm curious, can you describe more what this feels like?

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Offline demografx

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« Reply #14105 on: 22/07/2011 14:08:24 »





Our new POIS Forum - architectural genius: "daveman" - for detailed subject-by-subject discussion!
http://www.POISCenter.com/forums/index.php


Our 4-year-old POIS thread here at Naked Science Forum will also always remain open for newcomers, for general unstructured discussion, and historical research of the 10,000+ postings here since 2007.


We started a POIS Research Fund to boost our attack on The POIS Monster! Explained here:
http://poiscenter.com/forums/index.php?topic=125.0


We raised $2,150 in just the first 2 weeks, with much more pledged!


And your POIS fund donation is most welcome here:
http://rarediseases.org/about/support/research-donations




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Offline Starsky

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« Reply #14106 on: 22/07/2011 14:56:37 »
Isnt it so, that injectios are better for the liver? I have few bodybuilder friends and they say steroids taken oraly are bad so they make injections.

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Offline victor.kons

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« Reply #14107 on: 22/07/2011 14:57:37 »

XN Tablets Report.

...I have unhealthy feeling at the location of liver...


I'm curious, can you describe more what this feels like?
I can't explain to be fair how it feels, it is like there is some heaviness in the area of liver. Or it feels like I've screwed up, because tried the dose a bit higher than max dose in instruction, but I wanted to be sure that tablets can work too... Unfortunately you don't have XN in tablets easily available in USA and Europe, but from whatever reason I thought that you have.

I'm going to try Niacin Acid tablets next time. I had bought a pure Niacin Acid tablets, going to try usual dose this time - 50 mg, probably later today or tomorrow in the morning.

Victor
« Last Edit: 22/07/2011 15:42:53 by victor.kons »

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Offline victor.kons

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« Reply #14108 on: 22/07/2011 15:01:04 »
Isnt it so, that injectios are better for the liver? I have few bodybuilder friends and they say steroids taken oraly are bad so they make injections.
From my feelings yes - injections are better for the liver. But we need some easy way to test whether Niacin Acid works. The easiest test is taking some tablets, going into all the troubles with injections just to check if they help or not is scary thing. But in the long term, it might be the case that injection are healthier, we need to figure this out by getting consultation from doctors.

Victor

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Offline victor.kons

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« Reply #14109 on: 22/07/2011 17:21:28 »
Niacin Acid Tablets Report.

Took 100mg pure niacin acid tablets, half an hour before O. After two hours - no POIS symptoms.

Edit: At night I had a hard time to sleep and had a tension feelings in my head. Next day I've waken up with 20% of POIS I think, had the disgusting feeling of POIS beginning. I felt 10-20% POIS throughout the day. The second day was POIS free.

Victor
« Last Edit: 24/07/2011 08:17:07 by victor.kons »

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Offline horizon

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« Reply #14110 on: 22/07/2011 17:27:15 »
For me POIS on day 0 & 1 is basically ok 
Its day 2&3&4 i hate.
I dont know how you judge a pill after only a few hours.

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Offline victor.kons

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« Reply #14111 on: 22/07/2011 17:38:48 »
For me POIS on day 0 & 1 is basically ok 
Its day 2&3&4 i hate.
I dont know how you judge a pill after only a few hours.
Well, I have experience, I can feel when POIS will come and when it won't come. If I will make a mistake, I will report of course, but it feels okay.

Victor

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Offline horizon

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« Reply #14112 on: 22/07/2011 18:12:04 »
my experience, the less i get it at the start, the more i'll feel it on Day 3.
Best to judge whether a pill works after day 7 i'd say.

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Offline victor.kons

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« Reply #14113 on: 22/07/2011 18:33:17 »
my experience, the less i get it at the start, the more i'll feel it on Day 3.
Best to judge whether a pill works after day 7 i'd say.
I had generally 3 days POIS sessions before I started XN injections, while practicing XN injections 3 monthes ago I had 3 days terrible POIS when I decided to try whether I still have POIS or no. Couple of month ago I've changed my day schedule and I'm feeling really great: i get up at 4 am and go to bed at 10 pm. After I selected this schedule I think I'm more resistant to POIS, the last POIS I had couple of weeks ago, lasted only one day.

Warning! Don't try self-injecting on yourself without consultation of qualified medical personnel, you can make yourself permanent injury.

Victor
« Last Edit: 22/07/2011 19:33:26 by victor.kons »

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Offline victor.kons

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« Reply #14114 on: 23/07/2011 09:39:13 »
Niacin Acid Report, second day.

So, I've tried to take 100mg pure niacin acid in tablets to prevent POIS from starting yesterday.

Yesterday night I had a hard time to sleep and had a tension feelings in my head. Today I've waken up with 20% of POIS I think, had the disgusting feeling of POIS beginning. I had a thought - omg, am I going to break out to POIS completely.... After two hours of morning walk with my wife from 4 am to 6 am, I had a feeling of body fighting the POIS, and now I'm more or less okay hard to tell if I have POIS or no, but no negative symptoms.

Anyways, I'm failed this time. I'm going to wait several days and then try to increase niacin acid dose and try again.

Warning, please consult your doctor before trying to take any medications. Taking niacin acid might cause damage to your liver

Victor

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Offline jivetalk

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« Reply #14115 on: 23/07/2011 13:50:40 »

Anyways, I'm failed this time. I'm going to wait several days and then try to increase niacin acid dose and try again.


Victor, I think most of us here, me included would think that 20% POIS, that is, an 80% reduction in POIS is certainly NOT a failure.
Thank you for your reports here - They are invaluable to our understanding of what works and what does not. Most Certainly you Have NOT Failed, but are successful in helping to determine an effective treatment.

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Offline daveman

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« Reply #14116 on: 23/07/2011 14:57:48 »
Last night (at about 3AM, because I'm in day 2 today) I was remembering that when I was younger (about 30 or so), I would take Niacin and Vitamin C before going out for a big party where I knew I would be drinking and getting a good hangover, and then I'd take one maybe once during and before going to bed.

This reduced my hangovers dramatically. It would always surprise me! I can;t say they were stopped, but were down to maybe 20% of what it would have been. This was a consistent trick/cure.

So it remonds me a lot of all of this. As I was waking up this morning as a matter of fact, I felt as though I could just as easily be hung-over rather than entering POIS day 2. And it clicked. Is there something in common?

Alcohol also casues histamine release, I think because the system needs to get rid of the toxins caused by the alcohol assimilation. Does the Niacin raise the histamine release barrier or something. Can anybody think of some other mechanism?

I guess I'll have to look on internet to see if they say anything about this "hangover cure".

How does Murphey do it??

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Offline Habibou

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« Reply #14117 on: 23/07/2011 19:03:51 »
For me, it is a "too much" of histamine release due to the O/allergic reaction which creates the whole reaction. Perhaps due to a lack of the component used to "delete the effect of histamine". So that, alcohol which gets a lot of histamine naturally can be the explanation of the POIS symptoms feeling even after drinking little alcohol.

For my own case, when I drink  10 cl of a 12 wine (always french [:P]), I feel like I am in an intense POIS period... it feels like the triggers of my "POIS symptoms" are : O, alcohol and sport. After, I guess we are all different as we noticed by the past !
« Last Edit: 24/07/2011 02:29:20 by Habibou »

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Offline demografx

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« Reply #14118 on: 24/07/2011 05:09:38 »

Daveman, I've always felt a connection somehow between hangovers and POIS.

My hangovers were WAY out of proportion to what I imbibed. Often lasting DAYS.

I quit alcohol and anything else that could produce hangovers. Over 18 years ago.

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Offline hurray

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« Reply #14119 on: 24/07/2011 05:26:10 »
Thank you for the continued reports Victor - your experiments are helping us all! Especially since you have already found a cure for yourself - I for one am very happy that you are trying out the niacin/nicotinic acid solution orally. I dislike injections very much, and of course the injectable XN isn't easy to find in every part of the world.

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Offline victor.kons

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« Reply #14120 on: 24/07/2011 08:12:52 »
Thank you jivetalk, thank you hurray! Your support means very much to me. Jivetalk, your reports have very much value for us all and for me personally too!

So, day two is POIS free for me. I will edit my reports here and at pois center to reflect this.

Oral form of the drugs is certainly more convenient than injectable. But the thing is many of us have problems with digestion and from my experiments with oral niacin and XN pills I can say that they make digestion problems worser for couple of days. And I'm afraid that oral forms can't be long-term solution for those of us who have these problems with stomach. But it is still great as one-time solution in situation when injectable form is too inconvenient to bother with.

Please get a consultation from your doctor before trying any new drugs or making self-injection, you can do permanent injury to yourself, thank you.

Victor

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Offline Guthrie

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« Reply #14121 on: 24/07/2011 10:48:16 »
Hi all,

I also had a chance to test Niacin on myself.  On Thursday, I took 300 mg of Niacin on a mostly empty stomach, about 40 minutes before O.  The 'flush' came on pretty quickly (within 5 minutes or so); it was definitely quite noticeable and lasted about an hour--continuing for about 20 minutes after the O.

Results:
The O was at 6:00 pm.  In the hour or so immediately following the O, I felt better than usual.  I didn't feel the usual initial feelings of POIS 'creeping up.'  So that was a positive start.  However, later in the evening, I was feeling a bit out of it, so I began to think that the niacin hadn't prevented POIS. 

However, when I woke up the next morning (Friday), I found that I did NOT have the usual POIS brainfog and emotional/cognitive fatigue.  I would say that the POIS feelings were only at about 15-20% of their usual.  It was certainly a noticeable difference, so perhaps the niacin was effective!  Moreover, the 15-20% lasted throughout the whole day.

So, I would so that the initial experiment was a success.  I'm not sure what accounted for the less-good feelings of the later evening of Day 0, but Day 1 was certainly a big improvement.   Did the niacin simply shorten the POIS episode, so that it mostly ended while I slept on Thursday night?  Or perhaps it prevented POIS entirely, while the problems of the Day 0 evening were not POIS, but a reaction to the niacin.

In any case, I will need to test it again.  Perhaps I should use a little less niacin, since a one-hour flush seems a bit long.  But, it will be good to see if the overall effect is replicable, and if so, how the dosage affects things, and also whether being 'in flush' right at the moment of O makes a difference.


 

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Offline hurray

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« Reply #14122 on: 24/07/2011 12:23:35 »
Thank you also to jivetalk, silverandcol and Guthrie! Initial reports seem very promising indeed - I wish I could test niacin for myself, but it's not too easy to buy in my current location ...

All the reports so far seem positive with regards to reducing/eliminating POIS symptoms - perhaps we are on the verge of a breakthrough here  [:)]

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Offline demografx

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« Reply #14123 on: 24/07/2011 20:17:22 »

Very exciting developments!

Everyone reading this: please also heed victor.kons' cautionary remarks on the previous page.

Experiment with competent medical supervision only!

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Offline demografx

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« Reply #14124 on: 24/07/2011 20:21:37 »

Thank you also to jivetalk, silverandcol and Guthrie! Initial reports seem very promising indeed - I wish I could test niacin for myself, but it's not too easy to buy in my current location ...

All the reports so far seem positive with regards to reducing/eliminating POIS symptoms - perhaps we are on the verge of a breakthrough here  [:)]



On this first phase, if we have good success, (let's say 50% of us have 80% relief, or some similar indicator) we should look into why and how it is working. Because one thing is "breakthrough" in finding symptom relief, and another is "breakthrough" as in cure!

Only by identifying the whys and wherefors can we identify what type of breakthrough it is.

If it's not a cure, then, at some point in time it will come out and bite us. Perhaps continual use of XN / Niacin will damage our livers or we may drop investigation and research and find that it isn;t a cure or that it wears off with time or whatever.

So, yes, optimistic and enthiused, anxious, but extremely cautious.

Thanks everybody for the good and responsible (for the most part) testing!




EDIT: I accidentally deleted from iPhone so I reposted - demo
« Last Edit: 24/07/2011 21:21:06 by demografx »

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Offline Habibou

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« Reply #14125 on: 24/07/2011 22:25:31 »
Interesting things about Histamine on Wikipedia :

H3 histamine receptor = Found on central nervous system and to a lesser extent peripheral nervous system tissue    Decreased neurotransmitter release: histamine, acetylcholine, norepinephrine, serotonin.

Suppressive effects

While histamine has stimulatory effects upon neurons, it also has suppressive ones that protect against the susceptibility to convulsion, drug sensitization, denervation supersensitivity, ischemic lesions and stress.[9] It has also been suggested that histamine controls the mechanisms by which memories and learning are forgotten.

I personally take an H1 antihistamine which does not make anything on me, I should perhaps care of the H3 which has an important link with the brain ( memory/learning = cognitive)

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Offline B_Daniel

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« Reply #14126 on: 25/07/2011 00:59:23 »
French doctor David Servan-Schreiber is dead today. He was fighting a brain cancer. He was was a defender of nutrition as additional therapy. On a video he gave me the solution of the effect of sugar and high glycemic index food on inflammation that I consider as the best explanation for my Pois improvement since 2008.



That's unfortunate.  I have always known that when I eat a large unhealthy meal, or even something as simple as drink a soda with high fructose corn syrup, my brain fog becomes "horrifically" severe for 30mins - 3 hours.  Not like a big meal sleepiness, but like my brain just stops functioning at all.  Sometimes a stimulant like coffee can help reduce how bad it gets during those periods.  B_Jim, if you have more info on the inflammation link, I'd love to read it. 

This "inflammation" is another large puzzle piece that we need to ultimately hand over to our NORD selected researcher to aid him/her in understanding WHAT pois is and HOW is manifests its symptoms.   

« Last Edit: 25/07/2011 01:09:59 by B_Daniel »
2-5 days, 80% cognitive, tongue-tied, brain fog, lose track of thoughts mid conversation, anxiety, dry eyes, irritable, fatigue.  Believer of both auto-immune AND regeneration theories.  My sessions are much shorter when I've gone 2 wks without.

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Offline B_Daniel

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« Reply #14127 on: 25/07/2011 01:07:26 »
...I'll try B3 100mg this week.

Hey namesake! - I have so far bought nicotinamide ("niacinamide") and also Inositol Hexanicotinate - which are both niacin variations that do not provide the flush.  The right stuff to get is niacin (also known as vitamin B3, nicotinic acid and vitamin PP).  You likely already know this, just wanted to make doubly sure that no one else does what I did!
2-5 days, 80% cognitive, tongue-tied, brain fog, lose track of thoughts mid conversation, anxiety, dry eyes, irritable, fatigue.  Believer of both auto-immune AND regeneration theories.  My sessions are much shorter when I've gone 2 wks without.

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Offline demografx

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« Reply #14128 on: 25/07/2011 05:57:48 »

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Offline hurray

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« Reply #14129 on: 25/07/2011 12:28:25 »
Quote
On this first phase, if we have good success, (let's say 50% of us have 80% relief, or some similar indicator) we should look into why and how it is working. Because one thing is "breakthrough" in finding symptom relief, and another is "breakthrough" as in cure!

The early indications are that Dr Waldinger was right on the money - his method of treating an allergic reaction to semen is textbook medical science:

http://en.wikipedia.org/wiki/Allergen_immunotherapy

My uninformed guess would be that the niacin is depleting the body's supply of histamine, so that the POIS allergic reaction ends up being far less severe. I'm not knowledgable enough to understand the exact mechanism by which niacin might prevent POIS, but the link between histamines and allergic reactions is very strong - it seems very likely that niacin's interaction with histamines is the key to why niacin "works".

I don't think that niacin will end up being regarded as a cure, but it could well turn out to be the best short-term solution for dealing with day-to-day POIS. If it can work long-term without causing liver damage (as determined by regular blood tests), then it would be pretty amazing.

Dr Waldinger's semen desensitisation may well be the long-term cure, but only time can tell how effective it will be years from now. In the meantime, if niacin holds up, it could be the closest we have come so far to ridding ourselves of POIS.

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Offline demografx

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« Reply #14130 on: 26/07/2011 05:15:35 »


We started a POIS Research Fund to boost our final and fatal attack on The POIS Monster! Explained here:
http://poiscenter.com/forums/index.php?topic=125.0


We raised $2,150 in just the first 2 weeks, with much more pledged!


But we need $33,500. Please give today so we can get rid of POIS once and for all!
Go to the POIS Fund donation site and Let's Make It Happen, Everybody!

http://rarediseases.org/about/support/research-donations

« Last Edit: 26/07/2011 05:25:08 by demografx »

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Offline jivetalk

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« Reply #14131 on: 27/07/2011 06:35:19 »
Niacin Pills Report #4:

Okay Guys for this little experiment, I tried to do something which would normally have had me in VERY VERY POIS, cowering in a corner somewhere, shutting myself away from the world - completely unmotivated, lethargic, full of brain Fog and likely depressed. I have tried to O twice in two days - both times using Niacin (Nicotinic Acid Pills).

Monday Night:
Dosage: 3 x 100mg Nicotinic Acid Pills about 40 Minutes prior to O.

Straight after O, absoloutely no Brain Fog which is my main symptom straight after O. Was able to sleep fine - It seems that the Niacin Side Effects that I initially had are starting to wear off.

Tuesday Morning:
Woke up the next morning, was again absolutely amazed that I was NOT lethargic, and had Zero Brain Fog. It really is a DIFFERENT feeling waking up the next morning - expecting POIS but having NONE. Throughout the day, I maybe had 5-10% of Brain Fog - but it's hard to tell if this was due to brain fog or something else/stress/headache etc...

Tuesday Night:
Dosage: 3 x 100mg Nicotinic Acid Pills about 40 Minutes prior to O.

Same Scenario as previous night - No problems sleeping or overheating at all.

Wednesday Morning:
I woke up this morning, really really expecting POIS - some of Lethargy or brain fog at least. To my great suprise I had absotley NOTHING. It is currently about 3.21pm here - and I have had absolutely Zero symptoms all Day. I feel absolutely fantastic today - This is probably a combination of it being a Sunny day here AND the fact I have no POIS today, and are very excited by this little experiment.


Notes:
- I am VERY VERY excited by this test, I wanted to do something that would have for SURE put me in POIS previously.
- I did this test to prove to myself that this is NOT a PLACEBO effect.
- I made SURE that I took the Pills at least 30 mins Prior to O, and that I felt the FLUSH effect completely - and let it pass before O. I feel this is a critical component.
- I think that if you do not do the above, the damage would have already been done if you O - and these pills would only have little effect (although they still will have some).
- I will try to reduce my dosage soon, but at this stage am reluctant, as I am getting such good results.
- Please Keep posting our Results - GOOD or BAD.


If you will now excuse me, I am going to make some 'I LOVE B3' Tshirts to wear around. I think some of you here also made some promises about putting up posters of a certain Guy and his CAT  [;D]

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Offline victor.kons

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« Reply #14132 on: 27/07/2011 08:47:22 »
EXCELLENT results, thank you SO MUCH, I'm very glad for you jivetalk!

Victor
« Last Edit: 27/07/2011 08:49:29 by victor.kons »

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Offline horizon

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« Reply #14133 on: 27/07/2011 08:49:05 »
Yesterday took 2 x 500mg Niacin (on day 2) at 10pm.
Woke up at 3am with bad sunburn type effect, skin pain. Then woke in morning 7am feeling like I had 2/3 beers the night before.
Its not for me,
its the harshest food supplement ever. I think even smaller doses will be bad for my liver over time.

Pills, sunburn, hangover...like a night out in Ibiza without the fun.
« Last Edit: 27/07/2011 08:59:07 by horizon »

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Offline victor.kons

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« Reply #14134 on: 27/07/2011 09:05:52 »
Yesterday took 2 x 500mg Niacin (on day 2) at 10pm.
Woke up at 3am with bad sunburn type effect, skin pain. Then woke in morning 7am feeling like I had 2/3 beers the night before.
Sounds like a VERY BIG dose. I had feeling like that even from 100mg niacin acid tablet. You had dose 10 times bigger than me.

Thats why I like injections of XN, because I need pretty small dose and have no reaction neither from liver nor from stomach.

Its not for me,
its the harshest food supplement ever. I think even smaller doses will be bad for my liver over time.

Pills, sunburn, hangover...like a night out in Ibiza without the fun.
Not for me either, not a long time solution. XN injections is a long time solution for me.

Warning! Don't try self-injections without consulting from your doctor, you might cause permanent injury to yourself.

Victor

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Offline horizon

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« Reply #14135 on: 27/07/2011 10:41:48 »
Sounds like a VERY BIG dose. I had feeling like that even from 100mg niacin acid tablet. You had dose 10 times bigger than me.

lol, yeah i was abit complacent because it was only food supplement.

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Offline jivetalk

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« Reply #14136 on: 27/07/2011 13:33:50 »
Sounds like a VERY BIG dose. I had feeling like that even from 100mg niacin acid tablet. You had dose 10 times bigger than me.

lol, yeah i was abit complacent because it was only food supplement.

Hahaha...Horizon. I would encourage you to try a smaller dose - BEFORE Orgasm. Please do not dismiss Niacin because I feel you have not given it a fair chance.
Please consult with your doctor too though.

I feel that taking Niacin AFTER the event will do very little. I think Victor will also attest to that.

I think if you O without Niacin, DAMAGE is done. Therefore Taking Niacin afterwards will do little. By Taking Niacin prior - It somehow PREVENTS Damage, which means you do not get affected by POIS or at least get affected a lot less.

Note:  Please also ensure that it is Nicotinic Acid you are Taking - Also NOT Slow Release.
« Last Edit: 27/07/2011 13:39:44 by jivetalk »

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Offline jivetalk

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« Reply #14137 on: 27/07/2011 13:35:20 »
EXCELLENT results, thank you SO MUCH, I'm very glad for you jivetalk!

Victor

Thank YOU Victor. I must say, if it wasn't for you who came onto these forums and encouraged us to look at Niacin and Niacin Derivatives like XN - I would not have found this solution. So Thank YOU Victor - Very Very Much.

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Offline victor.kons

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« Reply #14138 on: 27/07/2011 13:41:00 »
Sounds like a VERY BIG dose. I had feeling like that even from 100mg niacin acid tablet. You had dose 10 times bigger than me.

lol, yeah i was abit complacent because it was only food supplement.

Hahaha...Horizon. I would encourage you to try a smaller dose - BEFORE Orgasm. Please do not dismiss Niacin because I feel you have not given it a fair chance.
Please consult with your doctor too though.

I feel that taking Niacin AFTER the event will do very little. I think Victor will also attest to that.

I think if you O without Niacin, DAMAGE is done. Therefore Taking Niacin afterwards will do little. By Taking Niacin prior - It somehow PREVENTS Damage, which means you do not get affected by POIS or at least get affected a lot less.
Yes, I completely agree with Jivetalk, - taking Niacin afterwards is doing little. Niacin should be taken prior to orgasm to prevent POIS symptoms.

Victor

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Offline Habibou

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« Reply #14139 on: 27/07/2011 14:29:43 »
Here is the pharmacokinetics of an oral pill and the optimal effect in the body :
(it can fluctuate, regarding the pills, but this is an average) Our next step is to know it for the Niacin/XN. If someone has it already?  [;D]

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Offline Starsky

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« Reply #14140 on: 27/07/2011 15:49:55 »
Victor.cons Do you know some russian trusted online pharmacies?

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Offline victor.kons

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« Reply #14141 on: 27/07/2011 17:11:50 »
Victor.cons Do you know some russian trusted online pharmacies?
Sorry, I don't know such pharmacies.

Victor

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Offline Starsky

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« Reply #14142 on: 27/07/2011 18:49:49 »
XN, 1000mg slow release pills dont work. I took 1 pill at 12 and after a while i felt light warm feeling in my face, had O. after 2h. What i feel: tension inside my head, you know what i mean, and im very tired and lazy. So im POISed

On the leaflet its sait 1000mg for 6-8 hours release. So after 2h i should have taken 300mg XN but as I said, it must be a quick action.
« Last Edit: 27/07/2011 19:26:33 by Starsky »

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Offline Quasar

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« Reply #14143 on: 27/07/2011 19:34:42 »
Hi all! I'm new. I'm from Europe, Spain. I think i suffer from POIS since i was 14 years old. I remember i began to suffer from brain fog and scalp pain and i didn't know what it was. Then one day i tried to stop masturbating for 1 week, and bingo! the symptoms were gone. I felt great. But stopping to masturbate is a difficult task. For the next years the symptoms have been more severe. What i experience now (30 year old) after masturbation:

- Dry skin (my face and body become dehydrated)
- Scalp pain: after masturbation my scalp is very tender to the touch
- Low energy
- Diziness when i stand up suddenly: orthostatic intolerance
- Strange feeling around my heart. Heart beats are more strong
- Severe hair loss
- Depressive and melancholic feelings

The only thing that helps me after POIS is going out and doing some jogging. Exercice helps me a lot. I don't know what i would do without exercice...Probably kill myself LOL.

Sometimes i think it is a cardiovascular issue. I mean, one part of the problem is when i have an orgasm, i can feel capillaries dilate! Specially in my scalp. I that's what's making the problem later. So, I know some of you tried Beta Blockers, and didn't work for you, but i still think it makes a lot of sense to try to prevent that capillary dilation in the first place.

When i have a dry orgasm, i can't feel the capillaries dilate in the same way. So, there we have a clue.

Also, i found interesting the Histamine issue, because it is also related with capillaries, and allergies.

I don't know if this page is a scam, but here it goes: http://www.restoreunity.org/natural_method_antihistamine.htm

It points out natural methods to stop histamine. It says this about Niacin:

"4.      Supplement the form of niacin called inositol hexanicotinate.  It can cross the blood brain barrier more effectively than niacin.  It has no flush, while niacin has a flush.  Niacin can increase cell membrane permeability.  Increasing cell permeability can improve the ability of supplements to penetrate into cells.  Dr. Bob advised 100 mg of hexanicotinate in the AM along with methionine supplementation. "

Also, i find it interesting to try Finasteride. It blocks DHT. Sometimes after masturbating i feel the problem could be converting too much testosterone to DHT. That would explain the huge hair loss i suffer instantly after masturbation.

Sorry for the long post!



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Offline demografx

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« Reply #14144 on: 27/07/2011 20:48:05 »

Quasar, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS resources which may be helpful to you:

Our new POIS Forum - architectural genius: "daveman" - for detailed subject-by-subject discussion!
http://www.POISCenter.com/forums/index.php
Our 4-year-old POIS thread here at Naked Science Forum will also always remain open for newcomers, for general unstructured discussion, and historical research of the 10,000+ postings here since 2007.

The Learning Channel's (TLC)  feature TV presentation on POIS, featuring our member here at this forum, "Animus". It was aired on May 22, 2011. Here is a link to the file for that TV documentary, "Desperate Measures", which can be downloaded and played. The segment starts at about 12:20..
http://www.fileserve.com/file/cUtJa9R/TITLE01.mp4

Our POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

The POIS Information Website is home to the famous POIS Forum Compendium, written by "Pyropeach", and contains theories already discussed here and treatments that have both worked and failed.

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:
http://www.youtube.com/watch?v=UWBxAUC9k1g

Our new POIS chatroom (realtime chat). Invite or visit another member(s) there, ANY TIME. We can all get to know each other better:
http://forums.delphiforums.com/POIS/chat


POIS Research Studies, 2011

These 2 papers reveal Dr. Waldinger's POIS autoimmune hypothesis and suggests one possible avenue of treatment.

First POIS Research Study, 2002

We have a copy of the first formal medical investigation on POIS by Prof. dr. Marcel D. Waldinger,MD,PhD, and Dr. Dave Schweitzer, MD.

  
Recent POIS Research Study, 2010

CASE REPORT
Postorgasm Illness Syndrome - A Spectrum of Illnesses
Jane Ashby, MRCP, and David Goldmeier, MRCP
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg316781#msg316781


British Medical Journal Case Report, 2010

Case study by Dr. Selwyn Dexter of a patient with a headache-featured POIS symptom treated with progesterone/norethisterone.
http://casereports.bmj.com/content/2010/bcr.10.2009.2359.short?rss=1


How to get any or all of the above 5 studies: send me or "daveman" a Private Message (PM) with your regular email address (use "AT" instead of "@" ) and we'll send you back the PDF(s).

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around the recipient's name, i.e., "demografx", or "daveman".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show our credibility to the medical world - which often shows little understanding and is sometimes skeptical of our condition: POIS has scientific underpinnings and POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapeutic community. All of this information can greatly help you to fight the immediate reaction of some doctors: so just tell them, "IT'S NOT 'ALL IN OUR HEADS'! "

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum, which has already been referenced in respectable sources such as the Journal of Sexual Medicine (Dr. Waldinger's study), British Medical Journal and wikipedia:
http://en.wikipedia.org/wiki/Postorgasmic_illness_syndrome

For over 4 years, our POIS forum has attracted over 200 POIS sufferers worldwide who have posted here, research on an additional 200 sufferers elsewhere on the internet, plus over 1,300,000 page visits. Not bad for a rare malady!



SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: more than 4 years' worth of posts (over  10,000 posts!) from 200+ Forum members, and an additional 200 POIS sufferers found elsewhere on the Internet by Member B_Jim.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://thenakedscientists.com/

for example, I tried
nocturnal emission POIS site:http://thenakedscientists.com/

and 740 results came up for "nocturnal emission" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.


« Last Edit: 27/07/2011 20:51:06 by demografx »

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Offline Counterpoints

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« Reply #14145 on: 27/07/2011 21:41:42 »
Can anyone comment on the important differences between niacin and niacinamide?  I read on wikipedia that niacin, once ingested, is converted to niacinamide.  Niacinamide will not cause a flush, and has some other effects.  I read in a health food store that niacinamide helps with metabolism more than niacin, but I have not been able to find this information elsewhere.  I have not yet had time to take a good look at the wiki pages, but I am curious what people are taking here -- Niacin or Niacinamide?

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Offline FinalPanic

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« Reply #14146 on: 27/07/2011 22:10:15 »
Hi all - long time since I have posted - but I do read on occasion. I have followed up an earlier post and have sent an email to Dr Goldmeier, I will let you know how I get on with this.

I seem to be suffering less - maybe only a day or two - it used to be several days. I do not know what has changed, but something has helped. I have given up smoking, alcohol (I used to do a lot of both), I eat a lot more fresh vegetables and less junk, I now also exercise regularly. I did try the Rellora thing for a while - it actually has helped me with underlying anxiety problems - it seems to have broken a vicious cycle in that respect. It is possible that a healthier lifestyle has improved my ability to cope, but as things are still not right I will see what response I get from Dr Goldmeier. All the best.

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Offline daveman

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« Reply #14147 on: 28/07/2011 00:25:56 »
Yesterday took 2 x 500mg Niacin (on day 2) at 10pm.
Woke up at 3am with bad sunburn type effect, skin pain. Then woke in morning 7am feeling like I had 2/3 beers the night before.
Its not for me,
its the harshest food supplement ever. I think even smaller doses will be bad for my liver over time.

Pills, sunburn, hangover...like a night out in Ibiza without the fun.


Horizon, No WONDER you felt bad. 2x500mg is a horrendous dosage, especially for a first time.

Even 3x100 is a fair bit, but between that and 1000mg there's a tremendous difference.

Hope you are better. Please be careful!
How does Murphey do it??

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Offline silverandcol

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« Reply #14148 on: 28/07/2011 00:40:17 »
Yesterday took 2 x 500mg Niacin (on day 2) at 10pm.
Woke up at 3am with bad sunburn type effect, skin pain. Then woke in morning 7am feeling like I had 2/3 beers the night before.
Its not for me,
its the harshest food supplement ever. I think even smaller doses will be bad for my liver over time.

Pills, sunburn, hangover...like a night out in Ibiza without the fun.


Horizon, No WONDER you felt bad. 2x500mg is a horrendous dosage, especially for a first time.

Even 3x100 is a fair bit, but between that and 1000mg there's a tremendous difference.

Hope you are better. Please be careful!


Yup, it is also not good for the body to take that much.  The xan-pro tablets I have only have 42mg of niacin and 150mg of XN.

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Offline B_Daniel

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« Reply #14149 on: 28/07/2011 05:56:04 »

If you will now excuse me, I am going to make some 'I LOVE B3' Tshirts to wear around. I think some of you here also made some promises about putting up posters of a certain Guy and his CAT  [;D]


That's hilarious!  First of all, I'd love an I heart B3 or maybe even a B3 is my Homeboy t-shirt.  Second, it'd be a bit cruel to have Demo hang up a picture of a banned former-member of the forum.  Victor, do you have a cat??  Maybe a picture of Victor would be a good compromise!  [;D]
2-5 days, 80% cognitive, tongue-tied, brain fog, lose track of thoughts mid conversation, anxiety, dry eyes, irritable, fatigue.  Believer of both auto-immune AND regeneration theories.  My sessions are much shorter when I've gone 2 wks without.