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Demo,I remember the first time you had an O while on daily Naicin, you were almost POIS-free (also huge part due to testosterone). Did you experience the flush then??
Hello Willem,could you please again summarize a bit your desensitization treatment1- when did you start and where2- how many injections have you received till now and concentrations3- percent of improvement you are feeling4- fresh or frozen samples each time?can't wait to hear it is working for you! thanks
Willem -You're doing the sublingual immunotherapy at home. I know there's probably some risk of shock and perhaps it's against medical advice to do this on your own so pls be as safe as possible about it, but I just wanted to personally say that I'm very excited for your results. I know you're waiting for conclusive evidence to share with us, so I'm waiting patiently until then. Also, i think you're a crazy pioneer/maverick for treating yourself with this and I give you a ton of credit for undertaking such an experiment!
Dear all,I discovered this forum a few days ago, but have been searching for this type of symptom occasionally on google for at least a year or two now. Glad to have finally found a place I can call home. There is some comfort just in knowing I am not alone.BRIEF SUMMARY/SYMPTOMS: 23 year old male, come from a slightly neurotic household but medical-oriented (father is a doctor). I work in a high finance trading job in a good city. Perfect genes, tough to pinpoint when symptoms started but it has gotten progressively worse over time. I suffer from post ejaculation fatigue, depression, clouded thought, difficulty focusing/concentrating, loss of libido, acne, lack of appetite (and I am already very skinny), weakened immune system, irritability/cynicism, very serious personality, sunlight sensitivity, disturbed sleep (lack of dreaming/deep sleep, wake up still very tired). My symptoms tend to occur in the 2-3 days afters ejaculating, (the worst being the morning after), but I feel some minor effects beginning right after orgasm. One year ago I developed acid reflux/heartburn, constant burping, and an endoscopy revealed a hiatal hernia. Very recently, symptoms have worsened, turning into mild nausea after eating, full blown anxiety and even downright panic attacks. At times it feels like I have too much adrenaline pumping through my veins, and at other times it feels like I am downright depressed. Doctors feel that the gastro issues are related to the anxiety, which has underlying depression as the cause. I began taking clonazepam as needed in past few weeks, but have had a mixed response so far. Doctor wants me to start on antidepressants like Zoloft and possible other medication.WHAT WORKS FOR ME: Tough to say since my symptoms seem to be getting worse but in general, when I take ZINC, it gives me libido (rock hard erections), energy, confidence, and helps with sleep, and helps to clear up acne blemishes, it also helps me to concentrate/think better. However, the effects are short lived as ejaculating seems to pull the zinc right out of me (my semen must have a tremendous amount of zinc content). Still, I cannot speak enough to the benefits of Zinc. I recently switched to Zinc Magnesium Calcium supplements. Exercise helps only in the immediate short term, releasing endorphins for me that make me feel good all around. Protein in general seems to help me recover faster. Sleep seems to help my body refresh its energy/hormonal levels, and I may suffer from chronic lack of sleep as I have a deviated septum so it may be that I have been getting slightly less than optimal amounts of sleep for several years now. Sunlight seems to help a bit, but I have not confirmed this for myself. Also, it seems to help when I try to lead an active lifestyle where I don't worry so much about trying to time ejaculations perfectly every X number of days, or time my meals at the same time, etc. Adding diversity to my daily activities/eating habits such as snacking, and random exercise, and random supplement taking, seems to help smooth out the symptoms and helps me to not focus on them so much. But I do not have a definitive cure yet.LOOKING FORWARD: I would really like to try Niacan based off the rave reviews on this forum. Will update on how that is going. Also will update if I start taking any antidepressants or other doctor-prescribed medication. Going to read through this forum more closely to find any other tips or tricks.ADDITIONAL THOUGHTS: I think some of my issues may have to do with depression/anxiety and its far reaching effects. I may also suffer from stress. It is also possible that my way of life creates too much adrenaline, which could somehow deplete vitamins/nurtrients (a lot of my symptoms trace back to when I starting getting interested in the stock market, business jobs, etc...basically the stress/adrenaline factor). So I definitely think it may be vitamin/nutrient related, which is why Zinc works so well at times. I think there is a psychological component to this but that it does not cover everything. I would like to contribute $$ to a cause that researches this more, though I come from a family that is very skeptical of giving donations due to fraud/scams these days. If there was a way that I could feel completely confident the money is going to a legitimate institution, I would be happy to contribute what I can now, and more over time. I should also note that I am definitely in favor of a shared excel spreadsheet that organizes everyones perosonal bios, symptoms, medical history, and treatments/cures.
Welcome traderwithpois! .... Please think it twice before deciding to take an antidepressant! Especially if it's an SSRI, like the Zoloft you mentioned. Some people gets worse Pois symptoms after having taken an SSRI. In fact, there is/was a group in Yahoo Groups called "SSRI-post sexual dysfunction". So, it would be wise to choose, if any, an antidepressant that has not sexual side effects. For example, Bupropion or Mirtazapine.
I've read people dying from that sort of therapy due to shock? Be careful
Quote from: rock27 on 10/09/2011 18:51:13Demo,I remember the first time you had an O while on daily Naicin, you were almost POIS-free (also huge part due to testosterone). Did you experience the flush then??Rocky,I think it was either placebo or coincidence, because I don't feel any ongoing POIS improvement apart from my successful TRT treatment. POIS is now about the same as in my pre-niacin days.I do have a number of nearly-POIS-free episodes routinely and I have yet to explain why! I was also instructed to begin niacin therapy with uncoated 325mg aspirin to COUNTER the flush, and then I continued with 325mg aspirin because that is normal protocol for posturgical bypass patients like me. I suspect the aspirin continues to counter the flush.
Quick summary: my high dose TRT + stimulants + forced (extra) sleep are extremely powerful POIS tools for me. At times, I am nearly 100% POIS-free. On average: 80%.Please do NOT try what I do without strict testing, diagnosis and medical supervision. It can be dangerous.After 35 years POIS agony, I can't begin to describe my gratitude these last 2+ years. I thank you - this forum - for showing me the way!
Quasar, thank you!Yes, Adderall was effective. Only because of insurance I switched to Ritalin. Equally effective.I also supplement with caffeine.I must stress: these are dangerous combinations, especially with TRT which is ALSO a stimulant! Especially for someone like me, a post-cardiac bypass surgery patient!
Ryuk,Welcome! I can imagine it is almost impossible to go through the 600 pages here; This community has therefore created a forum to discuss in topics,for example about the recent niacin solution:http://poiscenter.com/forums/index.php?topic=174.0then just click home to see the other topics, it's the best POIS overview we have right now.mod edit - bold emphasis mine
Quote from: demografx on 10/09/2011 02:01:52Quote from: B_Daniel on 09/09/2011 22:37:12I'm just one data point though.Gee.....and here I thought you were a swell human being.....where did I go wrong??? haha demo this where you went wrong... you missed the 1st question !  just joking!
Quote from: B_Daniel on 09/09/2011 22:37:12I'm just one data point though.Gee.....and here I thought you were a swell human being.....where did I go wrong??? 
I'm just one data point though.
I take niacin daily without effect:1) maybe the "spike" of niacin is needed, so my daily intake doesn't work possibly because I have built a tolerance to niacin and now my body doesn't "react", it simply has gotten used to it.2) I take 325mg aspirin at the same time, which may _counter_ the flush that is necessary for POIS treatment effectiveness.3) My ongoing and very successful POIS treatment with testosterone + stimulants maybe means that I'm not a good candidate for niacin?
Willem, what exact procedure do you use to prepare the diluted solution of semen? And do you just hold the solution under your tongue for a few seconds then spit it out?I will probably try it in the future considering I don't have money to spend on doctor visits and injection treatments.
Hi Everyone, Dave and Demo think it's alright to share preliminary results of my sublingual therapy so here goes:I've been doing the home therapy since May 2011. I started at 1:50,000 and now am at 1:167. Around 1:10,000, I started noticing dramatic improvements and have been about the same since then. Overall POIS is down over 50%. My mind/energy/motivation/sleep are 80% improved. My muscles and nerves are about 40% improved. Recuperation time has gone from 7 days to about 2 days. I've increased my O frequency from ~1X per week to ~2X per week (trying to get pregnant) and am still feeling pretty good. Vandemolen has mentioned that major improvements may also come at the 1:70 range so I'm looking forward to that. CAVEATS: Since I'm still in the escalation phase I get random side effects from the treatment that I never had from POIS such as: joint pain, intestinal irritation, and pulled muscles. It also induces a mild, baseline POIS, so maybe I'm being too aggressive, but the treatment itself is not that much fun. I've been out of town a few weeks and had to take a break from treatments and felt a lot better then, almost normal. In another 6 weeks or so I should be in the maintenance phase and stop reacting to the treatments. I'll have a real good idea then of the final outcome.
Quote from: apostate801 on 11/09/2011 19:05:30I've read people dying from that sort of therapy due to shock? Be carefulSublingual therapy?I guess I should of thought twice when I took 100% semen and put it under my tongue.
I am not going to lie about myself but I am a skeptic about this theory.
Hey,Even when i get aroused,i start getting a headache and i feel numbness and heaviness in my head.My neck becomes stiff and get a back ache.i find it difficult to even lift my head and it hurts only on one side and that is on the top right of my head.i feel memory loss and it is hard to read or remember anything also.The pain is consistent for several days.it even continuously hurts in the back of my right eye.Can i have brain aneurysm or hematoma???Doctors say it might be a migraine attack but medicines dont help and pain doesnt go for days.!!!Feels like right side of my brain is rigid or kind of dead..!!!I too get nocturnal emissions at times. What problem do i have? (
Quote from: demografx on 10/09/2011 16:23:21I take niacin daily without effect:1) maybe the "spike" of niacin is needed, so my daily intake doesn't work +possibly because I have built a tolerance to niacin and now my body doesn't "react", it simply has gotten used to it.2) I take 325mg aspirin at the same time, which may _counter_ the flush that is necessary for POIS treatment effectiveness.3) My ongoing and very successful POIS treatment with testosterone + stimulants maybe means that I'm not a good candidate for niacin?demo, u'd be surprised a lot of stimulants have niacin in them, coffee being the highest.I've also found it strange that what I think caused POIS for me (coffee) can also relieve it during an episode.
I take niacin daily without effect:1) maybe the "spike" of niacin is needed, so my daily intake doesn't work +possibly because I have built a tolerance to niacin and now my body doesn't "react", it simply has gotten used to it.2) I take 325mg aspirin at the same time, which may _counter_ the flush that is necessary for POIS treatment effectiveness.3) My ongoing and very successful POIS treatment with testosterone + stimulants maybe means that I'm not a good candidate for niacin?
All of us are coming into contact with 1:1 semen periodically so wouldn't we all face the risk of anaphylactic shock?
Wish me luck [with my Sublingual Immunotherapy Treatment Process].
Quote from: Willem on 12/09/2011 05:26:10SLIT infoDo you have to create the mixture everyday or will one liter be good til you get desensitized and increase the concentration
Do you stir the initial sample? Any idea how long a frozen sample is good for?
Mellivora, B_Daniel, Willem, Limejuice, Habibou and all: your concerns are well expressed and legitimate. Daveman and I will bring this up with Stefanie when she returns from a leave of absence in a few weeks. Many thanks for speaking your mind!Demo
Has anyone experimented with treatments after POIS starts? So I had an O last night then today I took 500mg of Niacin. I had the flush and felt some improvement over the symptoms but ended up with some lightheadness. It felt like POIS was still there and was returning after some time. Then I thought about how if this is an allergy, maybe Benadryl would help. I took an aspiring and Benadryl and felt some improvement after a few hours.