Post Orgasmic Illness Syndrome (POIS)

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Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17050 on: 30/07/2012 03:35:09 »
I bought Huperzine A about 8 hours ago and tried 100 mcg, which is approximately 2 pills from the bottle that I had bought.  Today is day 1 pois which is my worst stage.  I had O'd a couple of times yesterday unsuccessfully and POIS took its grip on me.  Huperzine A did nothing to combat my symptoms of POIS while in POIS.  I'm sure I would notice it out of POIS, but in POIS it didn't do anything.  I will probably continue taking it out while my worst symptoms subside.  Maybe it will help if I take it out of pois.

Don't think I said POIS enough :)

Dante, your theory sounds plausible, as I still am leaning towards the auto-immune "brain allergy" symptoms.
My next concoction for pois is to try flushing with niacin along with taking an antihistamine.

Hi GoingCrazy,
Huperzine just improves memory.That's why I'm taking a few different things.

Are you taking the b coenzymes?
Have you been taking ginkgo twice a day?
I'd also recommend some L-Taurine.

Perhaps if you do this for a few days without having an O then you might notice an improvement. I definitely have.

I am semi-ly taking vitamin b complex along with taking calcium magnesium, but only sometimes.  But so far on your list I believe I have only tried the huperzine A, to see if my POIS had anything to do with acetylcholine synthesis in my brain.  Sadly while in POIS in did not do much.  I agree that I should take it out of POIS to see of the affects, but I'll probably wait at least a month to see if you are still doing good.

No problem about the link
Bad news: the last 2 days Ive seen a slight increase in pois. I wish I hadnt prematurely gotten everyone's hopes up. My relief the past few days was VERY real though (100% not placebo) so there's something very improtant to Kurtosis' findings. Hopefully i just need a few weeks on them to really see a stabilized benefit. Who knows. I'll keep ya'll posted

It's ok.  Getting hopes up is better than no hope.

I'm thinking something in his concoction is stopping a reaction from occuring, possible allergic reaction.  I'm too lazy right now to find out which one.

----------------------

My brain isn't really fully functional right now as I had an accidental O around 5 am this morning, it has been 17 hours and I am almost out of it.  As soon as I O'd I popped a ceritizine (i think thats what its called) antihistamine... I literally ran downstairs and popped it to help with the symptoms.  It did help a little bit but I believe the affects are wearing off right now and I can feel my brain all swelled up.  I usually take the antihistamine before the O, but this time it was on accident and I was very disappointed that it happened.

But besides that, has anyone tried injecting themselves with oxytocin (and/or vasopressin, nitric oxide, prolactin) for an allergy test?  I can't get to my memory right now.  Besides assuming semen as the allergy, we really need to get a list of everything released upon orgasm in the brain that may be causing this and then go from there.
« Last Edit: 30/07/2012 03:43:39 by GoingCrazy »

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17051 on: 30/07/2012 09:26:49 »
I bought Huperzine A about 8 hours ago and tried 100 mcg, which is approximately 2 pills from the bottle that I had bought.  Today is day 1 pois which is my worst stage.  I had O'd a couple of times yesterday unsuccessfully and POIS took its grip on me.  Huperzine A did nothing to combat my symptoms of POIS while in POIS.  I'm sure I would notice it out of POIS, but in POIS it didn't do anything.  I will probably continue taking it out while my worst symptoms subside.  Maybe it will help if I take it out of pois.

Don't think I said POIS enough :)

Dante, your theory sounds plausible, as I still am leaning towards the auto-immune "brain allergy" symptoms.
My next concoction for pois is to try flushing with niacin along with taking an antihistamine.

Hi GoingCrazy,
Huperzine just improves memory.That's why I'm taking a few different things.

Are you taking the b coenzymes?
Have you been taking ginkgo twice a day?
I'd also recommend some L-Taurine.

Perhaps if you do this for a few days without having an O then you might notice an improvement. I definitely have.

I am semi-ly taking vitamin b complex along with taking calcium magnesium, but only sometimes.  But so far on your list I believe I have only tried the huperzine A, to see if my POIS had anything to do with acetylcholine synthesis in my brain.  Sadly while in POIS in did not do much.  I agree that I should take it out of POIS to see of the affects, but I'll probably wait at least a month to see if you are still doing good.

No problem about the link
Bad news: the last 2 days Ive seen a slight increase in pois. I wish I hadnt prematurely gotten everyone's hopes up. My relief the past few days was VERY real though (100% not placebo) so there's something very improtant to Kurtosis' findings. Hopefully i just need a few weeks on them to really see a stabilized benefit. Who knows. I'll keep ya'll posted

It's ok.  Getting hopes up is better than no hope.

I'm thinking something in his concoction is stopping a reaction from occuring, possible allergic reaction.  I'm too lazy right now to find out which one.

----------------------

My brain isn't really fully functional right now as I had an accidental O around 5 am this morning, it has been 17 hours and I am almost out of it.  As soon as I O'd I popped a ceritizine (i think thats what its called) antihistamine... I literally ran downstairs and popped it to help with the symptoms.  It did help a little bit but I believe the affects are wearing off right now and I can feel my brain all swelled up.  I usually take the antihistamine before the O, but this time it was on accident and I was very disappointed that it happened.

But besides that, has anyone tried injecting themselves with oxytocin (and/or vasopressin, nitric oxide, prolactin) for an allergy test?  I can't get to my memory right now.  Besides assuming semen as the allergy, we really need to get a list of everything released upon orgasm in the brain that may be causing this and then go from there.


Hi GC,
OK, I understand. Let me explain my motivation in the concoction I'm taking.

The b's, zinc and magnesium are about boosting testosterone levels, boosting my dopamine levels and making up for any deficiencies in b-vitamins that may be a result of hormone versus b-vit interactions, leaky gut or auto-immune illness. In conjunction with protein from the spirulina, niacin levels can be regulated and more testosterone can be produced. If the problem is sub-clinical pellagra brought about by testosterone / oestrogen imbalance then dairy protein may actually make it worse as there's oestrogen in cow's milk.

Ginkgo is about managing allergic and stress reactions in my brain (ginkgo extract has a number of beneficial compounds which have been shown in animal studies to do this) following an O, generally improving circulation and boosting neurogenesis in the hippocampus (where new memories are stored).

Both Krill oil and Ginkgo can reduce inflammation through COX-2 inhibition (although they work in different ways to achieve this).

However, if I had to pick an essential list of ingredients it would be in this order: b-coenzymes, zinc, ginkgo, fish-oil, magnesium, huperzine & if I was on a tight budget I'd take the first 3 with some extra taurine. 

The huperzine is only about boosting memory and it's synergistic vaso-dillatory effect with ginkgo. It's to help me recover from POIS memory "holes" but it's not what's reducing my POIS. I'm sure of that.
Of the ingredients, huperzine, similar to the piracetam I tried before it, will only benefit the brain once it's normalised and "out of POIS". It did improve my eyesight and I may have a mild acetylcholineserase problem. I'm still getting this tested. Otherwise it will do very very little for anybody with POIS without taking the other things.

The other thing I'm doing is actively trying to lower cortisol levels by not stressing about O's and going for long walks. Whenever I have an O, it's generally at night and I'm taking B+zinc+mag shortly after. About the only useful cortisol production is that associated with resistance training that also increases testosterone. If you think of our evolutionary origins, our endocrine systems didn't evolve in anticipation of us sitting in offices stressing and increasing our cortisol levels without running, fighting or hunting - activities which will also increase testosterone :) So much of the stress management problems males have may be the result of an asymmetry in cortisol and testosterone production combined with a lot of environmental exposure to oestrogen.

You could also have a high level of Test. but too high a level of Oestrogen meaning the ratio is wrong and you'd need to generate more T to compensate.

For example, have a look at what additive oestrogen does to rats
http://www.ncbi.nlm.nih.gov/pubmed/6231048

"led to a significant reduction in the liver content of nicotinamide nucleotides and the urinary excretion of the end-product of NAD metabolism, N1-methyl nicotinamide. It is suggested that when the diet is only marginally adequate in tryptophan and niacin, inhibition of tryptophan metabolism by endogenous or administered oestrogens may be an additional factor in the development of pellagra."

Anyway, off to get my hormone levels checked. I know my testosterone levels have increased but I haven't had oestrogen levels checked.

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Offline GDRTW

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17052 on: 30/07/2012 09:32:47 »
Just a qiuckie here. I have tried over the years with different 'power' foods/drinks to alleviate symptoms. I am a teacher so working in a class of students with POIS can be hell to say the least.  To me Red Bull works the best. Not something you want to drink too much off (recommended limit is no more than 2 per day), but in times of urgent need I go for it. I put it down to the taurine. I have seen people mention Taurine supplements. Not a bad call.

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Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17053 on: 30/07/2012 22:17:06 »
Just a qiuckie here. I have tried over the years with different 'power' foods/drinks to alleviate symptoms. I am a teacher so working in a class of students with POIS can be hell to say the least.  To me Red Bull works the best. Not something you want to drink too much off (recommended limit is no more than 2 per day), but in times of urgent need I go for it. I put it down to the taurine. I have seen people mention Taurine supplements. Not a bad call.

Funny because I have been working for 8 straight days without a day off and the day I had POIS I actually drank around 6 red bulls.  It isn't the best for reducing symptoms , I believe, but it was the only thing I had at the moment.   I believe either the caffeine or something else in it constricts the blood vessels in the brain which makes it easier to cope with during POIS.  If you do this you really need to cut out the red bull around 5 or 6 o'clock because I learned the hard way by not falling asleep until around 3-4 a.m.
« Last Edit: 30/07/2012 22:19:13 by GoingCrazy »

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Offline badgerstripe

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17054 on: 30/07/2012 22:34:18 »
I get a purple/red rash if i rub semen into my skin, its doesnt itch though.

All the recent posts are v interesting. I am still trying to get my recent expereiences with Niacin and Dr Goldmeier into a coherent form to post, not sure if its my busyness, tiredness or effects of POIS that have prevented me.

Its probably easiest to put my experience with Dr Goldmeier into bullet points:
* All blood tests (taken 1 day after an O were 'normal')
* Mindfulness practice has not had a great impact on POIS as far as i can see though i can see short term benefits on anxiety levels.
* It is apparently up to my G.P. to refer me to an allergist within the U.K's N.H.S.
* Before this can happen i need to try the strong antihistamine Dr G recommended. The letter prescribing this has taken many weeks to come through to my G.P., it is being chased up.
* I have another appointment with Dr G in September.
* I can still safely say that Zinc supplementation and the use of Niacin on an empty stomach, 20 mins to an hour before an O are having the greatest benefits for me. I started the Zinc many years ago after reading about orthomolecular treatment of histadelia, the more recent decision to use of Niacin also came from this literature. The strong recommendations and procedure for using Niacin came from members of this forum for which i will be forever grateful. I now have 2 or 3 'O's per week without strong POIS - this is nothing short of a miracle for me!

I have a feeling that having a diet rich in organic meat and veg and my complete avoidance of alcohol, drugs, nicotine, dairy and gluten have helped enormously in keeping my background level of health up. I tend to avoid sugar and caffeine as well and exercise moderately.

Good luck with this chaps. POIS has been such a challenge.


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Offline badgerstripe

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17055 on: 30/07/2012 22:41:15 »
Btw these were the tests done 1 day after an 'O', they were all NORMAL:

Thyroid, testosterone,prolactin, glucose, liver, kidney, blood screen ( anaemia etc), calcium.

Phosphates were low but subsequent testing showed them to be at a normal level, i am unsure how long after an 'O' this was, if i'd had my scientific head on i would have taken notice.. oh well..

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Offline Hoping

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17056 on: 31/07/2012 00:12:00 »
Hi guys, I have been suffering from the symptoms of POIS for my entire adult life (roughly 11 years).  Symptoms include brain fog, difficulty maintaining erections, depression, fatigue, anxiety, swelling of eyes, paleness, premature ejaculation, lack of motivation...the list goes on.

I seem to get POIS when I get aroused...the symptoms are significantly worse after ejaculation than before, but if I masturbate or have sex without ejaculation or orgasm I still have the symptoms to a lesser degree.

I have a few questions for you guys...I am going to see my allergist this upcoming Friday and I am supposed to provide a "specimen" sample of my semen for skin ***** testing. So here are my questions:

1). How long before the skin ***** testing should I wait to provide the sample? The doctor said the morning of the appointment is fine (appt is at 10:00 a.m.). I know that sperm dies rather quickly after leaving the male body...will this affect the results of the test if I wait several hours?

2). If I do have a reaction to my own semen, will I have to provide a sample every time before I am giving the hyposensitization therapy? Or will they freeze the specimen and use it until they run out?

3). It seems like talk about treatment with autlogous semen has died down recently, is it still a viable treatment procedure?

4). What is the Kurtosis protocol I keep hearing about? I can't find any exact listing of what it entails as far as vitamins and procedure.

5). Are there any new procedures that have had success?

I feel like the issue is definitely based in the hypothalamus/pituitary. My theory is that I become aroused and my pre-ejaculate flows through my seminal "plumbing" and interacts with T-lymphocytes in any small gaps in the plumbing. If I ejaculate the amount of fluid interacting with the lymphocytes is increased causing a more severe reaction. The T-lymphocytes reaction then triggers the release of histamine. The histamine causes cortisol to be released to suppress it. A prolonged allergic reaction will create a prolonged cortisol release, interfering with hormones and the pituitary. Also, elevated levels of histamine will interact with the hypothalamus in a negative way, causing neurotransmitters and their release to become imbalanced and possibly even decreasing them.

My symptoms are very similar to dopamine deficiency, which I think might play a key role in POIS.

Anyways, I would appreciate any feedback and I hope you guys are doing well.

Thanks,
Chris
Dante: I received an intradermal test from Dr. Nguyen and Dr. Bewtra at Creighton University. The semen was not diluted at all for the two intradermal injections. I collected a sample and immediately put it in the freezer (in a glass jar). I did this about a week before the test. A couple hours before the test, I moved the sample to the fridge and thawed it. I then put it on ice for the drive to the doctor's office. It remained on ice until it was injected. When it was injected, it looked fresh.

As I stated in my post describing the test experience, "...I received the p-r-i-c-k test as well as the intradermal injection tests since I wasn't entirely clear on which to ask for (Waldinger's study refers to "intracaneous injections" but calls it a p-r-i-c-k test.) Dr. Nguyen did not dilute the semen as Waldinger specified. The p-r-i-c-k tests showed a slight reaction (about 3x3mm wheal and erythema and a 5x5mm wheal and erythema). The intradermal reactions were huge. It was 25x30mm wheal and erythema and 15x30mm wheal and erythema. Waldinger says in his study that wheal and erythema less than 5mm is negative. (For those who don't know, the "wheal" is the red bump that appears and the "erythema" is the flaring out rash that surrounds the wheal. Measuring these two components gets the numbers I mentioned above). It's interesting to note that after the testing, I was hit by a bout of POIS fatigue and brain fog very quickly. Normally my POIS lingers for around 10 days. This time the symptoms hit me quick and hard. I fell into a deep sleep for an hour which helped symptoms. They didn't linger too badly."

Good luck! Please report your  results (here, and on the other forum). Some people have uploaded photos of their test results, which might be good if you can pull it off too

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Offline 0002ppdnuos

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17057 on: 31/07/2012 04:48:39 »
Hi GC,
OK, I understand. Let me explain my motivation in the concoction I'm taking.
...
That's what I've been wondering about.

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17058 on: 31/07/2012 08:03:26 »
Just a qiuckie here. I have tried over the years with different 'power' foods/drinks to alleviate symptoms. I am a teacher so working in a class of students with POIS can be hell to say the least.  To me Red Bull works the best. Not something you want to drink too much off (recommended limit is no more than 2 per day), but in times of urgent need I go for it. I put it down to the taurine. I have seen people mention Taurine supplements. Not a bad call.

Funny because I have been working for 8 straight days without a day off and the day I had POIS I actually drank around 6 red bulls.  It isn't the best for reducing symptoms , I believe, but it was the only thing I had at the moment.   I believe either the caffeine or something else in it constricts the blood vessels in the brain which makes it easier to cope with during POIS.  If you do this you really need to cut out the red bull around 5 or 6 o'clock because I learned the hard way by not falling asleep until around 3-4 a.m.

If I had 6 red bulls I wouldn't sleep for a week :) I remember having 3 in 1 day and I didn't sleep a wink that night. I don't remember feeling POIS then, just incredibly hyper and a bit sick the next day. Everybody is different I guess & I also don't drink coffee so I might be quite sensitive to caffeine.

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Offline Over it

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17059 on: 31/07/2012 14:41:39 »
Hi all,
I have been watching this forum for a couple of months now. Below in italics is a post I prepared about 2 weeks ago but never ended up posting it. I have decided to post it now because I believe I have discovered the cause of my POIS & a potential treatment.  It is my belief that chronic depression & prolonged periods of stress are/were the cause of my POIS. I say this because I recently purchased a bottle of “Executive Focus” by Swisse. I decided to buy this stuff after reading on the back of the bottle that it contained ginkgo biloba. I remembered reading somewhere that this was giving some people some relief from POIS. Despite my brooding scepticism I decided to try it because I was desperate & at the clutching @ the frayed ends of my sanity. I took one tablet & 10 minutes later my neck, back & pelvis start cracking (in a good way) & my whole body feels like it is straightening out. The vertebrae that usually jut out the back of my neck, causing me terrible discomfort, felt very odd in a very good way. The pain in my joints was all but gone. My mood was like I was 15 years old again (in a good way) & my eyes felt great.  Anyway, 3 days later and I have upped the dosage a bit as required & I’m feeling the best I have in 10 years. Orgasm is no big deal. It’s all normal. (I should note that I am experiencing decreased libido, however, I am glad of that).
I saw a doctor about 3 weeks ago armed with some information I had gathered from this forum in one last desperate attempt to overcome this affliction. I got my blood tested for the millionth time & it was all fine. After some probing into my personal life by the doc, he drew the conclusion that I had chronic depression & suggested I try antidepressant drugs &/or psych therapy. Of course I didn’t believe him & concluded he was a charlatan; I declined both treatments. It is not until after taking this exotic concoction of vitamins & herbs & feeling normal again that I realise how severely screwed-up, depressed & sick I was. I feel like a bit of a fool actually. So anyway I’m not 100%, it’s early days & I know I’m not out of the woods yet but I certainly think I am on the right track. I’m not entirely sure of what it is that is helping me but here is something written on the use of ginkgo biloba in the treatment of depression:
http://orthomolecular.org/library/jom/1996/articles/1996-v11n03-p168.shtml 
I sincerely hope something in what I have written is of use to someone. Below is a post written by a man (me) who dwelled in the land of the living dead for the past 10 years.
      ----------------------------------------------------------------------
 I am a 28 year old male & I have been suffering from POIS symptoms for the last 10 years or so, however, I was only ever convinced these symptoms were a direct consequence of orgasm a few years ago.  My symptoms are more or less in line with those described by others on this forum.  There is one symptom or feeling that a few contributors have mentioned that interests me. That is a “strange” sensation in the back of the head; like a headache, but not. For me, all these problems began with an adverse reaction to smoking marijuana. It was only the second time I had ever smoked marijuana & only had a very small amount. Almost immediately after smoking I got an intense surge of anger, panic & fear (in that order). I couldn’t overstate how frighting this was even if I tried. I literally thought I was going to die. It was essentially a psychotic episode. This event was also characterized by intense pressure in the head and a cold sensation in the body like my blood was running cold.  My body was shaking uncontrollably especially around the pelvis to the point I was becoming air-borne from my bed. After a few hours I was calm enough to sleep for a couple of hours. When I woke up I couldn’t believe it was not a dream & I felt like absolute crap. The pressure in my head was still there & that strange “dense” or “wet” feeling in the back of my head was still there. My train of thought was erratic & had difficulty closing my eyes. I had to sleep with the light on sometimes due to irrational fear.  I was unable to experience any joy after this event for a couple of years, be it from food, music, social interaction etc. The only relief from my absolute misery was orgasm & I probably developed a bit of an addiction. I started to suspect that it was making me feel worse afterward but a hit of pleasure in an otherwise desolate wasteland of misery was impossible to resist. Anyhow, after many years of feeling like a living corpse I developed debilitating joint, back & neck pain & stiffness. So I was now a crippled corpse. Doctors, peers & family had all but convinced me there was nothing wrong with me, probably because I am in social isolation for 97.5% of my life & they do not see how it affects me.  Anyway, fast-forward to present day – The misery has diminished somewhat, in a general sense but I still have that strange feeling in the back of my head & all the joint stiffness is still there & it has become obvious to me that orgasm & alcohol (often combined)  greatly exacerbate my  symptoms & I stumble across this forum. I feel I should point out that stress & worry also exacerbate my complaints but not to the extent of orgasm (probably a misery ratio of 1:3). I have a fairly high-stress job & I take it very seriously and worry a lot, even in my dreams (maybe I just can’t handle stress very well).
I, personally, cannot ignore the link between my marijuana experience & my POIS symptoms. It is also my feeling that an investigation into a semen allergy may be a step in the wrong direction. Everyone on this forum is remarkably learned, particularly in medicine & I’m not entirely comfortable to speak out of school, but I have to say I am quite surprised there is not more investigation into possible psychological factors at work here. The talk about dopamine all seems very plausible to me.   
            ----------------------------------------

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17060 on: 31/07/2012 18:38:55 »
Hi all,
I have been watching this forum for a couple of months now. Below in italics is a post I prepared about 2 weeks ago but never ended up posting it. I have decided to post it now because I believe I have discovered the cause of my POIS & a potential treatment.  It is my belief that chronic depression & prolonged periods of stress are/were the cause of my POIS. I say this because I recently purchased a bottle of “Executive Focus” by Swisse. I decided to buy this stuff after reading on the back of the bottle that it contained ginkgo biloba. I remembered reading somewhere that this was giving some people some relief from POIS. Despite my brooding scepticism I decided to try it because I was desperate & at the clutching @ the frayed ends of my sanity. I took one tablet & 10 minutes later my neck, back & pelvis start cracking (in a good way) & my whole body feels like it is straightening out. The vertebrae that usually jut out the back of my neck, causing me terrible discomfort, felt very odd in a very good way. The pain in my joints was all but gone. My mood was like I was 15 years old again (in a good way) & my eyes felt great.  Anyway, 3 days later and I have upped the dosage a bit as required & I’m feeling the best I have in 10 years. Orgasm is no big deal. It’s all normal. (I should note that I am experiencing decreased libido, however, I am glad of that).
I saw a doctor about 3 weeks ago armed with some information I had gathered from this forum in one last desperate attempt to overcome this affliction. I got my blood tested for the millionth time & it was all fine. After some probing into my personal life by the doc, he drew the conclusion that I had chronic depression & suggested I try antidepressant drugs &/or psych therapy. Of course I didn’t believe him & concluded he was a charlatan; I declined both treatments. It is not until after taking this exotic concoction of vitamins & herbs & feeling normal again that I realise how severely screwed-up, depressed & sick I was. I feel like a bit of a fool actually. So anyway I’m not 100%, it’s early days & I know I’m not out of the woods yet but I certainly think I am on the right track. I’m not entirely sure of what it is that is helping me but here is something written on the use of ginkgo biloba in the treatment of depression:
http://orthomolecular.org/library/jom/1996/articles/1996-v11n03-p168.shtml 
I sincerely hope something in what I have written is of use to someone. Below is a post written by a man (me) who dwelled in the land of the living dead for the past 10 years.
      ----------------------------------------------------------------------
 I am a 28 year old male & I have been suffering from POIS symptoms for the last 10 years or so, however, I was only ever convinced these symptoms were a direct consequence of orgasm a few years ago.  My symptoms are more or less in line with those described by others on this forum.  There is one symptom or feeling that a few contributors have mentioned that interests me. That is a “strange” sensation in the back of the head; like a headache, but not. For me, all these problems began with an adverse reaction to smoking marijuana. It was only the second time I had ever smoked marijuana & only had a very small amount. Almost immediately after smoking I got an intense surge of anger, panic & fear (in that order). I couldn’t overstate how frighting this was even if I tried. I literally thought I was going to die. It was essentially a psychotic episode. This event was also characterized by intense pressure in the head and a cold sensation in the body like my blood was running cold.  My body was shaking uncontrollably especially around the pelvis to the point I was becoming air-borne from my bed. After a few hours I was calm enough to sleep for a couple of hours. When I woke up I couldn’t believe it was not a dream & I felt like absolute crap. The pressure in my head was still there & that strange “dense” or “wet” feeling in the back of my head was still there. My train of thought was erratic & had difficulty closing my eyes. I had to sleep with the light on sometimes due to irrational fear.  I was unable to experience any joy after this event for a couple of years, be it from food, music, social interaction etc. The only relief from my absolute misery was orgasm & I probably developed a bit of an addiction. I started to suspect that it was making me feel worse afterward but a hit of pleasure in an otherwise desolate wasteland of misery was impossible to resist. Anyhow, after many years of feeling like a living corpse I developed debilitating joint, back & neck pain & stiffness. So I was now a crippled corpse. Doctors, peers & family had all but convinced me there was nothing wrong with me, probably because I am in social isolation for 97.5% of my life & they do not see how it affects me.  Anyway, fast-forward to present day – The misery has diminished somewhat, in a general sense but I still have that strange feeling in the back of my head & all the joint stiffness is still there & it has become obvious to me that orgasm & alcohol (often combined)  greatly exacerbate my  symptoms & I stumble across this forum. I feel I should point out that stress & worry also exacerbate my complaints but not to the extent of orgasm (probably a misery ratio of 1:3). I have a fairly high-stress job & I take it very seriously and worry a lot, even in my dreams (maybe I just can’t handle stress very well).
I, personally, cannot ignore the link between my marijuana experience & my POIS symptoms. It is also my feeling that an investigation into a semen allergy may be a step in the wrong direction. Everyone on this forum is remarkably learned, particularly in medicine & I’m not entirely comfortable to speak out of school, but I have to say I am quite surprised there is not more investigation into possible psychological factors at work here. The talk about dopamine all seems very plausible to me.   
            ----------------------------------------

Executive Focus contains B vitamins & ginkgo. Also brahmi which appears to boost immune function and improves memory via some unknown mechanism. Interesting.

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Offline ThereIsAcure

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17061 on: 01/08/2012 01:10:27 »
I am 35 yr old from Saudi.The last 4 yr of my life have been the worst , since I felt unable to find an explanation to my symptoms ( extreme fatigue, foggy thinking , muscle pain ) . I visited doctors of different discipline ( even tested sleep apnea ! ) and  finally my symptoms were attributed to early diabetes 2 and took medication to manage it , and made the necessary life style changes ,but the symptoms remained as is ...... I became really depressed as I battle the unknown!
The other thing that doctors could NOT explain to me is why my testesrone is extremely below the lower range ( of someone in late seventy !!! ) although my body buildup and hair volume and distribution is perfectly fine.
Reading the forum for the last 2 months made me correlate to different things mentioned by members . I will list them below:
@ During 2009, I took daily ( pure honey , organic black seeds , cinnamon ) and gradually my symptoms completely disappeared .... continued for a year with perfect stable health.I stopped the honey , black seeds and cinnamon  thinking I got cured .... 6 months later the symptoms emerged and unfortunately I could not source the same quality of what helped me ......
[ note: honey => is testesrone booster ( did boost mine during 2009 )
   Black seeds => rich in vit b and fatty acids ]
@ Late 2011, I stated taking the ultimate B complex ( solgar ) which also contains vit c 1000 mg.To my surprise,I felt a noticeable improvement after 2 weeks (full agreement with what kurtosis suggested )!!!
@ I have also noticed that if I take any strong antihistamine before an O , I will wake up the next day completely refreshed [ unlike if I don't take the antihistamine ] also the antihistamine overcomes my PE problem which I suffered fr long time. My antihistamine experience is similar to what members of this forum did mention.
Therefore, I believe POIS  has different ways of manifestation with a strong roots to deficiency theory.
I am sure with our collective efforts, a cure is achievable in the very near future.

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Offline Starsky

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17062 on: 01/08/2012 10:40:51 »
What antihistamine did you take?

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Offline alphaq

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17063 on: 01/08/2012 20:18:20 »
anyone have psychological symptoms of pois? like OCD, paranoia, etc

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Offline alphaq

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17064 on: 01/08/2012 20:19:22 »
Or any personality changes and mood fluctuations?

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Offline ThereIsAcure

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17065 on: 01/08/2012 20:45:18 »
What antihistamine did you take?


Zyrtec or Xyzal

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Offline ThereIsAcure

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17066 on: 01/08/2012 20:58:48 »
Or any personality changes and mood fluctuations?
Yes. Mood fluctuation and sometimes severe depression .

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Offline Prancer

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17067 on: 01/08/2012 22:35:04 »
Were you officially diagnosed with early type 2 diabetes ThereIsAcure, or did the doctors just assume that is what you had? Either way you said the medication had no effect on your POIS. I wonder if it is not related to POIS if in fact you did have it.

The last time I had my blood sugar checked, they said it was fine (maybe even a little low, which I blame on my POIS).

anyone have psychological symptoms of pois? like OCD, paranoia, etc

Yes, I think I have mild OCD while in POIS.
« Last Edit: 01/08/2012 22:41:02 by Prancer »

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Offline ThereIsAcure

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17068 on: 02/08/2012 01:34:27 »


What I was trying to say is :
Yes, I was officially diagnosed and was able to manage the diabetes condition successfully , but my symptoms remain unchanged proving they were unrelated to diabetes.

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Offline FireCat

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17069 on: 02/08/2012 01:37:05 »
After four weeks of taking Niacin 500mg/day, I have to say that it works pretty fine on me, but not a total cure.

Niacin is great in a sense that it does reduce back pain after O.
I don't have to see a chiropractor after O to fix it anymore.

However, Niacin does not reduce fatigue symptoms much in general, and it also seems to increase sexual appetite.

As I wrote on my previous post, control of O is one of the keys to me, and I would see how it goes.

I would try something else to add to Niacin soon, but I thank this forum to give me Niacin.

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Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17070 on: 02/08/2012 02:58:25 »
I usually just take a claritin 24-hour antihistamine about an hour before sex.  I don't notice POIS if I take claritin.  I am just a bit drowsy but I guess that is normal while on an antihistamine plus post-orgasm.

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Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17071 on: 02/08/2012 02:59:26 »
anyone have psychological symptoms of pois? like OCD, paranoia, etc

Yes, when I don't do anything to combat my POIS.  I believe it is a symptom of an inflammed brain caused by POIS.

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Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17072 on: 03/08/2012 12:38:29 »
I usually just take a claritin 24-hour antihistamine about an hour before sex.  I don't notice POIS if I take claritin.  I am just a bit drowsy but I guess that is normal while on an antihistamine plus post-orgasm.
Hey GC, have you tried any other antihistamines by chance? I have tried cetrzine and zirtec, for hayfever relief. They were good, but I have to admit I never noticed any significnat benefit with pois. I actually think it might have helped things a bit with brain fog but it certainly no omg effect.

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Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17073 on: 03/08/2012 12:46:10 »
anyone have psychological symptoms of pois? like OCD, paranoia, etc
Yes. In my teens & early 20s. It faded after that. I was being treated for CFS and doing a number of things so whether it changed exclusively due to that or just faded with age I don't know. It was quite stressful and it made it hard to relax & enjoy life. I didn't see a doctor about it specificaly because I felt bad about saying I had some sort of mental problem at that age. I picked up that an O seem to exacerbate things, but did not consider it was exclusively due to orgasm.

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Offline amijgoro

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17074 on: 03/08/2012 13:28:06 »
Hi again, 

Don't know if you guys remember me (hope you do). I posted a short while back a message talking about my constant pois and the horrible symptoms it's accompanied with. During the past few months in which time I have learned about pois and the triggers to it, I've stopped masturbating. Going celibate wasn't enough to stop the symptoms though. I would have pois symptoms constantly. I've realized the constant pois was being caused by physical contact to the penis. Any simple and light touch including the rubbing of my boxers can trigger it. The worst symptoms it causes is awful cognitive disfunction and immediate physical fatigue that can actually put me to sleep. The moment this happens I also have the urgent need to pee which ends up all foamy in the toilet. I went to a urologist who had no idea what i was talking about. Although in the end he did give me a valuable piece Of information which is the reason behind the foamy urine. It could be explained by semen in the mixture of my pee, meaning semen is somehow getting into my bladder which is causing my symptoms (because of pois of corse). This phenomenon is called retrograde ejaculation. It happens when the shutter between the bladder and prostate doesn't shut tight enough. 
Stimulating the penis causes sperm to be released and enter the bladder through the weakened shutter or actually makes the shutter weak and allows a flow of semen into the bladder.

I can't take feeling like this every day anymore! 
Help regarding treatment would be most welcome.

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Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17075 on: 04/08/2012 00:18:24 »
amijgoro, what you are going through is pretty severe. Any physical contact to your penis!! I assume it has to be a stimulating sensation, and not just from even urinating. From what I read here foamy urine is not a typical pois symptom. In your case though the faulty plumbing seems to be causing a greater problem for you, combined with you being young with a hair trigger penis. So your urologist came up the 'shutter between the bladder and prostate doesn't shut tight enough' diagnosis. Can he operate to remedy this situation? That would be my first line of attack, given that there is no definitive cure on this site....though there have been a number of sufferers here recently who have made a lot of progress. You should read the posts from the past month especially, and try some of the supplements/meds.

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Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17076 on: 04/08/2012 01:19:57 »
I usually just take a claritin 24-hour antihistamine about an hour before sex.  I don't notice POIS if I take claritin.  I am just a bit drowsy but I guess that is normal while on an antihistamine plus post-orgasm.
Hey GC, have you tried any other antihistamines by chance? I have tried cetrzine and zirtec, for hayfever relief. They were good, but I have to admit I never noticed any significnat benefit with pois. I actually think it might have helped things a bit with brain fog but it certainly no omg effect.

I have tried Ceterizine (whatever you call it), but that was taken after my orgasm and it didn't do much.  Other than that I have only tried claritin 24-hour at least an hour before sex.

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Offline amijgoro

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17077 on: 04/08/2012 12:14:34 »
amijgoro, what you are going through is pretty severe. Any physical contact to your penis!! I assume it has to be a stimulating sensation, and not just from even urinating. From what I read here foamy urine is not a typical pois symptom. In your case though the faulty plumbing seems to be causing a greater problem for you, combined with you being young with a hair trigger penis. So your urologist came up the 'shutter between the bladder and prostate doesn't shut tight enough' diagnosis. Can he operate to remedy this situation? That would be my first line of attack, given that there is no definitive cure on this site....though there have been a number of sufferers here recently who have made a lot of progress. You should read the posts from the past month especially, and try some of the supplements/meds.

I took to what my urologist said a little differently. What i understood from the meeting was because the shutter isn't tight enough and semen is leaking into my bladder and the overall fact that i have pois is the combination why i think im having these terrible symptoms. I searched the internet for some sort of medication/supplement that could possibly tighten the shutter and reverse the retrograde ejaculation. I found that sudafed a sinus and cold congestion relief medication has that exact effect. i tried out the sudafed and miraculously it worked! I didn't have that hair trigger penis anymore. the only problem was that the actual medication itself was making me feel very bad and brain fogged, an effect that has been haunting me with medication for a long time now (medication including ritalin and other anti depression/ anxiety drugs). my conclusion from that is 1. The problem is the shutter being week and semen leaking into my bladder that is causing the symptoms. 2. The pois that im experiencing understood by semen escaping the prostate being the cause of the symptoms mean that its the semen that is the problem! And thirdly my boddy has a serious problem regarding bad reactions to a large range of medications that needs an explanation.

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Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17078 on: 04/08/2012 19:10:58 »
amijgoro, what you are going through is pretty severe. Any physical contact to your penis!! I assume it has to be a stimulating sensation, and not just from even urinating. From what I read here foamy urine is not a typical pois symptom. In your case though the faulty plumbing seems to be causing a greater problem for you, combined with you being young with a hair trigger penis. So your urologist came up the 'shutter between the bladder and prostate doesn't shut tight enough' diagnosis. Can he operate to remedy this situation? That would be my first line of attack, given that there is no definitive cure on this site....though there have been a number of sufferers here recently who have made a lot of progress. You should read the posts from the past month especially, and try some of the supplements/meds.

I took to what my urologist said a little differently. What i understood from the meeting was because the shutter isn't tight enough and semen is leaking into my bladder and the overall fact that i have pois is the combination why i think im having these terrible symptoms. I searched the internet for some sort of medication/supplement that could possibly tighten the shutter and reverse the retrograde ejaculation. I found that sudafed a sinus and cold congestion relief medication has that exact effect. i tried out the sudafed and miraculously it worked! I didn't have that hair trigger penis anymore. the only problem was that the actual medication itself was making me feel very bad and brain fogged, an effect that has been haunting me with medication for a long time now (medication including ritalin and other anti depression/ anxiety drugs). my conclusion from that is 1. The problem is the shutter being week and semen leaking into my bladder that is causing the symptoms. 2. The pois that im experiencing understood by semen escaping the prostate being the cause of the symptoms mean that its the semen that is the problem! And thirdly my boddy has a serious problem regarding bad reactions to a large range of medications that needs an explanation.

Very interesting Amigoro!  Maybe you could start with a very small dose and slowly increase to the recommended doseage?

Info on Sudafed for retrograde ejaculation: http://retrogradeejaculation.info/

Has anyone tried Sudafed against POIS? Is it possible that the "allergy" is initiated by partial retrograde ejaculation?

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Offline dante88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17079 on: 04/08/2012 21:26:19 »
I have noticed that I have very "foamy" urine after ejaculation as well. It is a different type of foam than I usually have when urinating...if I leave it in the toilet without flushing it will stay foamy and won't go away...I believe that retrograde ejaculation is the culprit. This would explain what is causing the allergic reaction.

I went to see my allergist yesterday and had a skin ***** test performed. I had a positive reaction to my own semen and the doctor has decided to put me on a strong antihistamine (Zaditen SRO). The doctor is still waiting on the results of my blood test to determine whether or not to perform hypo sensitization therapy.

I have noticed that my symptoms seem to be magnified if I masturbate to pornography as opposed to having sex with my girlfriend or masturbating w/o pornography. I believe that this is due to the increased dopamine consumption correlated with pornography.

To summarize my theory...the allergic reaction interferes with the functioning of the pituitary/hypothalamus..decreasing the amount of dopamine the body is able to produce and release. Pornography uses up the dopamine and POIS makes the body unable to replenish dopamine levels.

I have had other allergic reactions in the past...namely a reaction to the iodine found in some shellfish. The reaction that I had was very similar to what I experience with POIS...reaffirming that for me, POIS is an allergic reaction.

Taking  an antihistamine like zyrtec seems to abate the symptoms somewhat. Also I have been taking Niacinimide recently at roughly 2500 mg. It does seem to help with the symptoms as well...but it doesnt not cure them.

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Offline Prancer

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17080 on: 04/08/2012 22:35:06 »
To summarize my theory...the allergic reaction interferes with the functioning of the pituitary/hypothalamus..decreasing the amount of dopamine the body is able to produce and release.

That makes a lot of sense to me Chris. I really like that theory. My symptoms are also very similar to a dopamine deficiency. I always tried to connect having an allergy with dopamine deficiency, and that helps a lot.

-----------

Also, it's been several days now since I started taking the vitamins. They definitely seem to have a positive effect on me. What's really nice about them is I feel more rested in the morning and remember my dreams more often, and that helps a lot with my POIS symptoms. I also feel a bit more energized during the day. Of course, I need to keep taking them for a longer time, like kurtosis said, to really see how they're working. It's definitely not a POIS cure, but at least they seem to be showing some nice effects. Either way though, I think I would still take many of these vitamins even without POIS, as they are beneficial to one's overall health.

Prancer

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Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17081 on: 05/08/2012 00:16:02 »
By the way I have noticed foamy urine in the past as well. I remember urinalysis finding protein in the urine, and some minor hematuria (microscopic blood in the urine).

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Offline alphaq

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17082 on: 05/08/2012 06:01:09 »
Yes. In my teens & early 20s. It faded after that. I was being treated for CFS and doing a number of things so whether it changed exclusively due to that or just faded with age I don't know. It was quite stressful and it made it hard to relax & enjoy life. I didn't see a doctor about it specificaly because I felt bad about saying I had some sort of mental problem at that age. I picked up that an O seem to exacerbate things, but did not consider it was exclusively due to orgasm.

The interesting thing is many of the symptoms of POIS seem to resemble CFS, both physical and cognitive. It would be interesting to know if anyone else has had CFS and POIS, or had a severe or chronic viral infection before POIS

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Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17083 on: 05/08/2012 06:03:31 »
I have noticed that my symptoms seem to be magnified if I masturbate to pornography as opposed to having sex with my girlfriend or masturbating w/o pornography. I believe that this is due to the increased dopamine consumption correlated with pornography.
I have noticed the exact same. pois is definitely worse from jerking off to porn compared to having sex. There is a bit off a catch 22 here though. For some of us pois makes it hard to pick up girls or get a girlfriend...and its hello Allie Sin/Tia Ling. lol.  I have always believed dopamine was a key part of the issue and it has been discussed here before, but pushed in the background as other theories have come up. Wish it was easy to test for neurotransmitters (one recognised by conventional medicos).
Some of the symptons I had like agitation, anxiousness, paranoia I thought could actually be attributed to excess dopamine....still I tick off most things on the dopamine deficiency check list except limb problems. Google the 'edge effect' which is an article/book from a doctor who specialised in balancing neurotransmitters.
I tried the herb macuna puriens which is supposed to help raise dopamine and I had mixed results. The first time I took it I definitely thought it helped with pois, (but I was also on antibiotics at some time), the next two times no. The quality of this herb can be quite variable, but the last lot I got I seeked out a good quality version. I tried an antidepressant that was supposed to help on the dopamine front and it made no difference. I continue to take Tyrosine and that helps a bit but its no cure.
Have you read articles that can prove there is a different dopamine response with pornography compared to sex? Fooling around in bed with a sexy woman for an hour is very pleasurable and stimulating.

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Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17084 on: 05/08/2012 06:10:01 »
Yes. In my teens & early 20s. It faded after that. I was being treated for CFS and doing a number of things so whether it changed exclusively due to that or just faded with age I don't know. It was quite stressful and it made it hard to relax & enjoy life. I didn't see a doctor about it specificaly because I felt bad about saying I had some sort of mental problem at that age. I picked up that an O seem to exacerbate things, but did not consider it was exclusively due to orgasm.

The interesting thing is many of the symptoms of POIS seem to resemble CFS, both physical and cognitive. It would be interesting to know if anyone else has had CFS and POIS, or had a severe or chronic viral infection before POIS
Its certainly not an over whelming number but there have been a number of posters on this forum who have admitted to also having CFS. Yes is there a lot of overlap. CFS is bascially a waste paper basket diagnosis, for where they dont really know whast wrong with you. I don't have CFS really bad these days and work fulltime, and pretty much could say the majority of my symptoms fall under pois. My blood tests show I am fighting an infection, but my blood tests have not come back positive for any of the well known infections.

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17085 on: 05/08/2012 11:06:52 »
I have noticed that my symptoms seem to be magnified if I masturbate to pornography as opposed to having sex with my girlfriend or masturbating w/o pornography. I believe that this is due to the increased dopamine consumption correlated with pornography.
I have noticed the exact same. pois is definitely worse from jerking off to porn compared to having sex. There is a bit off a catch 22 here though. For some of us pois makes it hard to pick up girls or get a girlfriend...and its hello Allie Sin/Tia Ling. lol.  I have always believed dopamine was a key part of the issue and it has been discussed here before, but pushed in the background as other theories have come up. Wish it was easy to test for neurotransmitters (one recognised by conventional medicos).
Some of the symptons I had like agitation, anxiousness, paranoia I thought could actually be attributed to excess dopamine....still I tick off most things on the dopamine deficiency check list except limb problems. Google the 'edge effect' which is an article/book from a doctor who specialised in balancing neurotransmitters.
I tried the herb macuna puriens which is supposed to help raise dopamine and I had mixed results. The first time I took it I definitely thought it helped with pois, (but I was also on antibiotics at some time), the next two times no. The quality of this herb can be quite variable, but the last lot I got I seeked out a good quality version. I tried an antidepressant that was supposed to help on the dopamine front and it made no difference. I continue to take Tyrosine and that helps a bit but its no cure.
Have you read articles that can prove there is a different dopamine response with pornography compared to sex? Fooling around in bed with a sexy woman for an hour is very pleasurable and stimulating.

Any obvious difference would be levels of oxytocin. This reduces anxiety levels (including cortisol) but will be produced in greater quantities when you have sex with someone you love/care for. Or that's the theory anyway.
Interesting paper at http://www.ncbi.nlm.nih.gov/pubmed/20557568

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Offline alphaq

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17086 on: 06/08/2012 00:12:27 »
Anyone here that have both mental and physical symptoms that don't really go away even not having an 'O' for a while?

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Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17087 on: 06/08/2012 02:26:48 »
Anyone here that have both mental and physical symptoms that don't really go away even not having an 'O' for a while?

there a couple of us like that including me.

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Offline Mer

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17088 on: 06/08/2012 04:48:59 »
Let's assume that one decides to go to the gym to work out for the first time. This person has 10 units of age (not necessarily years) and thus is at an age group in which it is common to go to gym and work out. However, this person suffers from some deficiency of compounds x,y, and z due to some nutritional as well as genetic reasons. Due to his age and other factors he is interested and willing to do work out as his peers do. In his first work out session at the gym he manages to spend a normal amount of time doing the work out. Due to tension and contractions present during lifting his muscle tissues get damaged as expected. However, this person's body cannot heal this muscle tissue damage in a time period that would be considered normal. Due to the extended period of muscle damage symptoms such as fatigue are present and also during this extended period of time other bodily activities also get affected and do not function properly; such as adequate blood flow to different parts of body such brain. Consequently cognitive symptoms also appear. Therefore, the person for example experiences brain fog or head aches.

It is concluded that his deficiency of components x,y and z made his body unable to recover from that tissue damage and thus unpleasant symptoms were experienced by this individual.

In an effort to counter the effect of the symptoms the person has tried to consume a variety of foods with different nutritional characteristics. Foods and vitamins turned out to have positive effects on healing the symptoms by for example shortening the duration of healing. It turns out that some remedies are so well chosen that significantly reduce the recovery time.  All that this person has been doing was to put his body in such a state that quickly heals after workout activity; similar to how his peers feel about their body.

Are our bodies experiencing a similar scenario about ejaculation/sexual stimulation/orgasm? Do we have some deficiencies in our body that makes us unable to recover after orgasm in a "normal" length of time? Do cognitive and psychological symptoms appear in the mean time in which our body is struggling to heal from the change caused by ejaculation/sexual stimulation/orgasm? Does it also cause temporary tissue alteration at different part of body which causes less blood flow to the brain?

Do our bodies just lack components x, y, and z and thus unable to heal quickly after ejaculation/sexual stimulation/orgasm?


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Offline makrofag

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17089 on: 06/08/2012 08:32:37 »

Do our bodies just lack components x, y, and z and thus unable to heal quickly after ejaculation/sexual stimulation/orgasm?



My question would be. Why is the heck is there a lack of x,y,z components? It's cool that you can put something in you that increases your wellbeing but the deficiencies are only a symptom of a different problem.

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Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17090 on: 07/08/2012 05:38:18 »

Do our bodies just lack components x, y, and z and thus unable to heal quickly after ejaculation/sexual stimulation/orgasm?



My question would be. Why is the heck is there a lack of x,y,z components? It's cool that you can put something in you that increases your wellbeing but the deficiencies are only a symptom of a different problem.

Well, my only problem with this would be the way I developed POIS.  I was able to have an orgasm whenever I wanted.  I could have done it multiple times a day if I really wanted to.  So I don't think my body was lacking the "x,y,z components" at least at the time.  Maybe I could have slowly lost these nutrients, or the capability of producing these nutrients that my body needed to recover. 

But the thing is, I think POIS is much worse than a void of certain nutrients.  If it were then everybody experiencing POIS would just be tired after orgasm.  Nothing really explains all of the other symptoms.  At least the ones that I have.  The irritability, migraine, etc.  I think POIS is a much worse reaction than a simple loss in nutrients.

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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17091 on: 07/08/2012 07:09:04 »

Do our bodies just lack components x, y, and z and thus unable to heal quickly after ejaculation/sexual stimulation/orgasm?



My question would be. Why is the heck is there a lack of x,y,z components? It's cool that you can put something in you that increases your wellbeing but the deficiencies are only a symptom of a different problem.

Well, my only problem with this would be the way I developed POIS.  I was able to have an orgasm whenever I wanted.  I could have done it multiple times a day if I really wanted to.  So I don't think my body was lacking the "x,y,z components" at least at the time.  Maybe I could have slowly lost these nutrients, or the capability of producing these nutrients that my body needed to recover. 

But the thing is, I think POIS is much worse than a void of certain nutrients.  If it were then everybody experiencing POIS would just be tired after orgasm.  Nothing really explains all of the other symptoms.  At least the ones that I have.  The irritability, migraine, etc.  I think POIS is a much worse reaction than a simple loss in nutrients.

Deficiencies of some vitamins or proteins can cause nausea, joint pain, dementia-like symptoms, allergies, stomach pain, chronic fatigue...
How this comes about is very unclear but there are auto-immune illnesses that just strike without warning and previous illness as, due to unfortunate circumstance, the body's own cells appear as invaders and antibodies are produced against them. That aspect of POIS is not really so mysterious but it's apparent rarity is the real mystery. Why are others not presenting with similar symptoms and is it due to physiological rarity or social perception of the disease?

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Offline rock27

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17092 on: 07/08/2012 17:45:38 »
amijgoro, what you are going through is pretty severe. Any physical contact to your penis!! I assume it has to be a stimulating sensation, and not just from even urinating. From what I read here foamy urine is not a typical pois symptom. In your case though the faulty plumbing seems to be causing a greater problem for you, combined with you being young with a hair trigger penis. So your urologist came up the 'shutter between the bladder and prostate doesn't shut tight enough' diagnosis. Can he operate to remedy this situation? That would be my first line of attack, given that there is no definitive cure on this site....though there have been a number of sufferers here recently who have made a lot of progress. You should read the posts from the past month especially, and try some of the supplements/meds.

I took to what my urologist said a little differently. What i understood from the meeting was because the shutter isn't tight enough and semen is leaking into my bladder and the overall fact that i have pois is the combination why i think im having these terrible symptoms. I searched the internet for some sort of medication/supplement that could possibly tighten the shutter and reverse the retrograde ejaculation. I found that sudafed a sinus and cold congestion relief medication has that exact effect. i tried out the sudafed and miraculously it worked! I didn't have that hair trigger penis anymore. the only problem was that the actual medication itself was making me feel very bad and brain fogged, an effect that has been haunting me with medication for a long time now (medication including ritalin and other anti depression/ anxiety drugs). my conclusion from that is 1. The problem is the shutter being week and semen leaking into my bladder that is causing the symptoms. 2. The pois that im experiencing understood by semen escaping the prostate being the cause of the symptoms mean that its the semen that is the problem! And thirdly my boddy has a serious problem regarding bad reactions to a large range of medications that needs an explanation.

Amigoro,
what are the ingredients of the Sudafet? Where I live we don't have Sudafet, but I can look for other cold congestion relief medication that has more or less the same ingredients. Many thanks!

I also have this "oil"on top of urine. And when I leave my first urine after ejaculation a night in a bottle, it has many white clouds in it.
POIS, fatigue, brain fog, can't find words, irritated, can't concentrate.

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Offline Prancer

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17093 on: 07/08/2012 22:42:58 »
So I wonder if anyone has ever tried an anti-androgen. They're sometimes used by people who have a hair loss problem or who have severe acne, but a side effect is lower sex drive. I came across a site where they were talking about reducing their drive because some of them are orgasm addicts.(http://www.eunuch.org/forums/showthread.php?1018-30-Days-of-Androcur). One of the interesting things I read was that it made one of the users clear minded and relaxed after taking it. It also significantly reduces semen volume. Many of the POISers here also have a very high libido, including me. I always wondered if a very high libido is a symptom of POIS, or if it is the other way around. I'm very casually thinking about trying something like this, but I wouldn't take such high doses that the users are taking over there, as I would want to lower my drive, not eliminate it. At the very least, it would reduce the amount of orgasms I have and allow me to abstain for way, way longer.

This is just a question and not a recommendation to anyone. Also, there are a few side effects such as hot flashes lower muscle density.
« Last Edit: 07/08/2012 22:59:22 by Prancer »

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Offline Stef

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17094 on: 08/08/2012 01:58:44 »
Hello All!

I haven't posted here in quite a while, but wanted to mention something that I hope you'll find encouraging regarding the NORD POIS research fund.  It occurred to me after receiving a question about the fund from an NSF forum member.

Your fund is well over $10,000 -- and very active.

I know that there was quite a bit of concern -- especially at first -- that your fund money could be moved to another fund if your goal wasn't met in a certain time. This is because our guidelines, posted on our website, state how and when funds are sometimes transferred -- something that we never, ever want to do -- and rarely have done (I mean RARELY!!) in the seven years that I've been administering the grant program.

We know that money donated to NORD for scientific research -- donated by individuals and/or groups for a particular rare disease -- is not just money.

Those donations represent  hope...and more importantly -- a real chance for a cure!

NORD's research grant program is not, and never will be, a lucrative program for NORD.  It was never meant to be a profit-maker, and was borne directly out of the desperation that people with rare disorders realistically feel.  The research has to begin with patient's donations -- it's the sad reality.

But the outcomes can -- -- and frequently have been -- WONDERFUL!! :-)
 
Our policy also states that the transfer of money is up to the discretion of NORD, which simply means that if there is interest expressed -- not even donations made -- genuine interest via emails or phone calls, inquiring about a particular fund -- we will not touch that fund.

Absolutely -- without question -- your POIS scientific research fund at NORD is 100% safe and sound.  Once a fund reaches $10,000 -- there is no way, whatsoever, that the funds will EVER be moved. You heard it here! :-)

That's A LOT OF MONEY for a beginning seed grant fund!!!!  If those of you who have pledged funds could meet those pledges -- you'd have an AMAZING research fund --> your first ever, scientifically sound and meaningful POIS research!

The minimum amount to post your grant (in March, 2013) is $33,500. You men (and any women who read this forum) would be crazy not to go for this!!!

In addition, the Indiegogo campaign to raise research funds for your NORD grant is just about ready to roll.  It will need your involvement! You'll be able to tell the world about this horrendous disorder, while raising money for solid, scientific research -- your ticket out of this nightmare.

And you may very well be saving the lives of others with POIS who happen onto the upcoming Indigogo POIS campaign -- they will find light and encouragement, instead of darkness and hopelessness.

You can read more about the POIS Indiegogo campaign at http://poiscenter.com/forums/index.php?topic=454.0 and  http://poiscenter.com/forums/index.php?topic=489.0.  It will likely be launched some time in the next two weeks -- so please do keep checking on it at those links.

EACH OF YOU CAN PLAY A VERY IMPORTANT ROLE IN THAT CAMPAIGN -- DON'T DOUBT IT FOR ONE MOMENT!

Wishing everyone the best -- and keep the faith!!

Stef




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Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17095 on: 08/08/2012 07:05:23 »
So I wonder if anyone has ever tried an anti-androgen. They're sometimes used by people who have a hair loss problem or who have severe acne, but a side effect is lower sex drive. I came across a site where they were talking about reducing their drive because some of them are orgasm addicts.(http://www.eunuch.org/forums/showthread.php?1018-30-Days-of-Androcur). One of the interesting things I read was that it made one of the users clear minded and relaxed after taking it. It also significantly reduces semen volume. Many of the POISers here also have a very high libido, including me. I always wondered if a very high libido is a symptom of POIS, or if it is the other way around. I'm very casually thinking about trying something like this, but I wouldn't take such high doses that the users are taking over there, as I would want to lower my drive, not eliminate it. At the very least, it would reduce the amount of orgasms I have and allow me to abstain for way, way longer.

This is just a question and not a recommendation to anyone. Also, there are a few side effects such as hot flashes lower muscle density.
It is interesting that Demografx has been "cured" effectively by testosterone patches which would have the opposite effect of an anti-androgen.

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Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17096 on: 08/08/2012 14:53:59 »
Absolutely -- without question -- your POIS scientific research fund at NORD is 100% safe and sound.  Once a fund reaches $10,000 -- there is no way, whatsoever, that the funds will EVER be moved. You heard it here! :-)
(I sent the PM)
That's very good to hear!
When I gave money at first, I thought even if it goes to other funds it's OK to help other causes, but that's why I didn't give more for now.
It's amazing to think we have 25000 (or more) with the pledges and 10000 in the fund.

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Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17097 on: 08/08/2012 14:58:53 »
So I wonder if anyone has ever tried an anti-androgen.
That's what Dr Waldinger was using at first to help POIS sufferers. I think he was using a small dose of flutamide but this should be confirmed.
 

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Offline amijgoro

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17098 on: 08/08/2012 18:26:41 »
amijgoro, what you are going through is pretty severe. Any physical contact to your penis!! I assume it has to be a stimulating sensation, and not just from even urinating. From what I read here foamy urine is not a typical pois symptom. In your case though the faulty plumbing seems to be causing a greater problem for you, combined with you being young with a hair trigger penis. So your urologist came up the 'shutter between the bladder and prostate doesn't shut tight enough' diagnosis. Can he operate to remedy this situation? That would be my first line of attack, given that there is no definitive cure on this site....though there have been a number of sufferers here recently who have made a lot of progress. You should read the posts from the past month especially, and try some of the supplements/meds.

I took to what my urologist said a little differently. What i understood from the meeting was because the shutter isn't tight enough and semen is leaking into my bladder and the overall fact that i have pois is the combination why i think im having these terrible symptoms. I searched the internet for some sort of medication/supplement that could possibly tighten the shutter and reverse the retrograde ejaculation. I found that sudafed a sinus and cold congestion relief medication has that exact effect. i tried out the sudafed and miraculously it worked! I didn't have that hair trigger penis anymore. the only problem was that the actual medication itself was making me feel very bad and brain fogged, an effect that has been haunting me with medication for a long time now (medication including ritalin and other anti depression/ anxiety drugs). my conclusion from that is 1. The problem is the shutter being week and semen leaking into my bladder that is causing the symptoms. 2. The pois that im experiencing understood by semen escaping the prostate being the cause of the symptoms mean that its the semen that is the problem! And thirdly my boddy has a serious problem regarding bad reactions to a large range of medications that needs an explanation.

Amigoro,
what are the ingredients of the Sudafet? Where I live we don't have Sudafet, but I can look for other cold congestion relief medication that has more or less the same ingredients. Many thanks!

I also have this "oil"on top of urine. And when I leave my first urine after ejaculation a night in a bottle, it has many white clouds in it.

The component in sudafed that tightens the sphincter is called Psuedoephedrine.
The med worked well with the original problem but gave me bad side effects (these side effects come about in many medications that I took in the past so don't dismiss it because of my personal body function).

The oil you describe floating on your pee I have too (I never let my pee sit overnight yet so I can't tell you if I have white clouds as well) both discribe semen in the urin.
This web site talks about different remedies that can help with retrograde ejaculation:

http://www.mayoclinic.com/health/retrograde-ejaculation/DS00913/DSECTION=treatments-and-drugs

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Offline Stef

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17099 on: 08/08/2012 22:10:37 »
Once again, hello!

I've just been advised that the Indiegogo campaign is online now!!

Please go to www.indiegogo.com/research-for-POIS and check it out.  There are major ways that you can participate and make this campaign really successful. 

Daveman at poiscenter.com is the Team Leader if you have questions.

I'm wishing you all the best of luck with this fund raiser for your POIS research grant!

Stef