[alphaq]

Yes. In my teens & early 20s. It faded after that. I was being treated for CFS and doing a number of things so whether it changed exclusively due to that or just faded with age I don't know. It was quite stressful and it made it hard to relax & enjoy life. I didn't see a doctor about it specificaly because I felt bad about saying I had some sort of mental problem at that age. I picked up that an O seem to exacerbate things, but did not consider it was exclusively due to orgasm.

The interesting thing is many of the symptoms of POIS seem to resemble CFS, both physical and cognitive. It would be interesting to know if anyone else has had CFS and POIS, or had a severe or chronic viral infection before POIS

[acronym]

I have noticed that my symptoms seem to be magnified if I masturbate to pornography as opposed to having sex with my girlfriend or masturbating w/o pornography. I believe that this is due to the increased dopamine consumption correlated with pornography.

I have noticed the exact same. pois is definitely worse from jerking off to porn compared to having sex. There is a bit off a catch 22 here though. For some of us pois makes it hard to pick up girls or get a girlfriend...and its hello Allie Sin/Tia Ling. lol.  I have always believed dopamine was a key part of the issue and it has been discussed here before, but pushed in the background as other theories have come up. Wish it was easy to test for neurotransmitters (one recognised by conventional medicos).
Some of the symptons I had like agitation, anxiousness, paranoia I thought could actually be attributed to excess dopamine....still I tick off most things on the dopamine deficiency check list except limb problems. Google the 'edge effect' which is an article/book from a doctor who specialised in balancing neurotransmitters.
I tried the herb macuna puriens which is supposed to help raise dopamine and I had mixed results. The first time I took it I definitely thought it helped with pois, (but I was also on antibiotics at some time), the next two times no. The quality of this herb can be quite variable, but the last lot I got I seeked out a good quality version. I tried an antidepressant that was supposed to help on the dopamine front and it made no difference. I continue to take Tyrosine and that helps a bit but its no cure.
Have you read articles that can prove there is a different dopamine response with pornography compared to sex? Fooling around in bed with a sexy woman for an hour is very pleasurable and stimulating.

[acronym]

Yes. In my teens & early 20s. It faded after that. I was being treated for CFS and doing a number of things so whether it changed exclusively due to that or just faded with age I don't know. It was quite stressful and it made it hard to relax & enjoy life. I didn't see a doctor about it specificaly because I felt bad about saying I had some sort of mental problem at that age. I picked up that an O seem to exacerbate things, but did not consider it was exclusively due to orgasm.

The interesting thing is many of the symptoms of POIS seem to resemble CFS, both physical and cognitive. It would be interesting to know if anyone else has had CFS and POIS, or had a severe or chronic viral infection before POIS

Its certainly not an over whelming number but there have been a number of posters on this forum who have admitted to also having CFS. Yes is there a lot of overlap. CFS is bascially a waste paper basket diagnosis, for where they dont really know whast wrong with you. I don't have CFS really bad these days and work fulltime, and pretty much could say the majority of my symptoms fall under pois. My blood tests show I am fighting an infection, but my blood tests have not come back positive for any of the well known infections.

[kurtosis]

I have noticed that my symptoms seem to be magnified if I masturbate to pornography as opposed to having sex with my girlfriend or masturbating w/o pornography. I believe that this is due to the increased dopamine consumption correlated with pornography.

I have noticed the exact same. pois is definitely worse from jerking off to porn compared to having sex. There is a bit off a catch 22 here though. For some of us pois makes it hard to pick up girls or get a girlfriend...and its hello Allie Sin/Tia Ling. lol.  I have always believed dopamine was a key part of the issue and it has been discussed here before, but pushed in the background as other theories have come up. Wish it was easy to test for neurotransmitters (one recognised by conventional medicos).
Some of the symptons I had like agitation, anxiousness, paranoia I thought could actually be attributed to excess dopamine....still I tick off most things on the dopamine deficiency check list except limb problems. Google the 'edge effect' which is an article/book from a doctor who specialised in balancing neurotransmitters.
I tried the herb macuna puriens which is supposed to help raise dopamine and I had mixed results. The first time I took it I definitely thought it helped with pois, (but I was also on antibiotics at some time), the next two times no. The quality of this herb can be quite variable, but the last lot I got I seeked out a good quality version. I tried an antidepressant that was supposed to help on the dopamine front and it made no difference. I continue to take Tyrosine and that helps a bit but its no cure.
Have you read articles that can prove there is a different dopamine response with pornography compared to sex? Fooling around in bed with a sexy woman for an hour is very pleasurable and stimulating.

Any obvious difference would be levels of oxytocin. This reduces anxiety levels (including cortisol) but will be produced in greater quantities when you have sex with someone you love/care for. Or that's the theory anyway.
Interesting paper at http://www.ncbi.nlm.nih.gov/pubmed/20557568

[alphaq]

Anyone here that have both mental and physical symptoms that don't really go away even not having an 'O' for a while?

[CertainlyPOIS]

Anyone here that have both mental and physical symptoms that don't really go away even not having an 'O' for a while?

there a couple of us like that including me.

[Mer]

Let's assume that one decides to go to the gym to work out for the first time. This person has 10 units of age (not necessarily years) and thus is at an age group in which it is common to go to gym and work out. However, this person suffers from some deficiency of compounds x,y, and z due to some nutritional as well as genetic reasons. Due to his age and other factors he is interested and willing to do work out as his peers do. In his first work out session at the gym he manages to spend a normal amount of time doing the work out. Due to tension and contractions present during lifting his muscle tissues get damaged as expected. However, this person's body cannot heal this muscle tissue damage in a time period that would be considered normal. Due to the extended period of muscle damage symptoms such as fatigue are present and also during this extended period of time other bodily activities also get affected and do not function properly; such as adequate blood flow to different parts of body such brain. Consequently cognitive symptoms also appear. Therefore, the person for example experiences brain fog or head aches.

It is concluded that his deficiency of components x,y and z made his body unable to recover from that tissue damage and thus unpleasant symptoms were experienced by this individual.

In an effort to counter the effect of the symptoms the person has tried to consume a variety of foods with different nutritional characteristics. Foods and vitamins turned out to have positive effects on healing the symptoms by for example shortening the duration of healing. It turns out that some remedies are so well chosen that significantly reduce the recovery time.  All that this person has been doing was to put his body in such a state that quickly heals after workout activity; similar to how his peers feel about their body.

Are our bodies experiencing a similar scenario about ejaculation/sexual stimulation/orgasm? Do we have some deficiencies in our body that makes us unable to recover after orgasm in a "normal" length of time? Do cognitive and psychological symptoms appear in the mean time in which our body is struggling to heal from the change caused by ejaculation/sexual stimulation/orgasm? Does it also cause temporary tissue alteration at different part of body which causes less blood flow to the brain?

Do our bodies just lack components x, y, and z and thus unable to heal quickly after ejaculation/sexual stimulation/orgasm?

[makrofag]

Do our bodies just lack components x, y, and z and thus unable to heal quickly after ejaculation/sexual stimulation/orgasm?

My question would be. Why is the heck is there a lack of x,y,z components? It's cool that you can put something in you that increases your wellbeing but the deficiencies are only a symptom of a different problem.

[GoingCrazy]

Do our bodies just lack components x, y, and z and thus unable to heal quickly after ejaculation/sexual stimulation/orgasm?

My question would be. Why is the heck is there a lack of x,y,z components? It's cool that you can put something in you that increases your wellbeing but the deficiencies are only a symptom of a different problem.

Well, my only problem with this would be the way I developed POIS.  I was able to have an orgasm whenever I wanted.  I could have done it multiple times a day if I really wanted to.  So I don't think my body was lacking the "x,y,z components" at least at the time.  Maybe I could have slowly lost these nutrients, or the capability of producing these nutrients that my body needed to recover. 

But the thing is, I think POIS is much worse than a void of certain nutrients.  If it were then everybody experiencing POIS would just be tired after orgasm.  Nothing really explains all of the other symptoms.  At least the ones that I have.  The irritability, migraine, etc.  I think POIS is a much worse reaction than a simple loss in nutrients.

[kurtosis]

Do our bodies just lack components x, y, and z and thus unable to heal quickly after ejaculation/sexual stimulation/orgasm?

My question would be. Why is the heck is there a lack of x,y,z components? It's cool that you can put something in you that increases your wellbeing but the deficiencies are only a symptom of a different problem.

Well, my only problem with this would be the way I developed POIS.  I was able to have an orgasm whenever I wanted.  I could have done it multiple times a day if I really wanted to.  So I don't think my body was lacking the "x,y,z components" at least at the time.  Maybe I could have slowly lost these nutrients, or the capability of producing these nutrients that my body needed to recover. 

But the thing is, I think POIS is much worse than a void of certain nutrients.  If it were then everybody experiencing POIS would just be tired after orgasm.  Nothing really explains all of the other symptoms.  At least the ones that I have.  The irritability, migraine, etc.  I think POIS is a much worse reaction than a simple loss in nutrients.

Deficiencies of some vitamins or proteins can cause nausea, joint pain, dementia-like symptoms, allergies, stomach pain, chronic fatigue...
How this comes about is very unclear but there are auto-immune illnesses that just strike without warning and previous illness as, due to unfortunate circumstance, the body's own cells appear as invaders and antibodies are produced against them. That aspect of POIS is not really so mysterious but it's apparent rarity is the real mystery. Why are others not presenting with similar symptoms and is it due to physiological rarity or social perception of the disease?

[rock27]

amijgoro, what you are going through is pretty severe. Any physical contact to your penis!! I assume it has to be a stimulating sensation, and not just from even urinating. From what I read here foamy urine is not a typical pois symptom. In your case though the faulty plumbing seems to be causing a greater problem for you, combined with you being young with a hair trigger penis. So your urologist came up the 'shutter between the bladder and prostate doesn't shut tight enough' diagnosis. Can he operate to remedy this situation? That would be my first line of attack, given that there is no definitive cure on this site....though there have been a number of sufferers here recently who have made a lot of progress. You should read the posts from the past month especially, and try some of the supplements/meds.

I took to what my urologist said a little differently. What i understood from the meeting was because the shutter isn't tight enough and semen is leaking into my bladder and the overall fact that i have pois is the combination why i think im having these terrible symptoms. I searched the internet for some sort of medication/supplement that could possibly tighten the shutter and reverse the retrograde ejaculation. I found that sudafed a sinus and cold congestion relief medication has that exact effect. i tried out the sudafed and miraculously it worked! I didn't have that hair trigger penis anymore. the only problem was that the actual medication itself was making me feel very bad and brain fogged, an effect that has been haunting me with medication for a long time now (medication including ritalin and other anti depression/ anxiety drugs). my conclusion from that is 1. The problem is the shutter being week and semen leaking into my bladder that is causing the symptoms. 2. The pois that im experiencing understood by semen escaping the prostate being the cause of the symptoms mean that its the semen that is the problem! And thirdly my boddy has a serious problem regarding bad reactions to a large range of medications that needs an explanation.

Amigoro,
what are the ingredients of the Sudafet? Where I live we don't have Sudafet, but I can look for other cold congestion relief medication that has more or less the same ingredients. Many thanks!

I also have this "oil"on top of urine. And when I leave my first urine after ejaculation a night in a bottle, it has many white clouds in it.

[Prancer]

So I wonder if anyone has ever tried an anti-androgen. They're sometimes used by people who have a hair loss problem or who have severe acne, but a side effect is lower sex drive. I came across a site where they were talking about reducing their drive because some of them are orgasm addicts.(http://www.eunuch.org/forums/showthread.php?1018-30-Days-of-Androcur). One of the interesting things I read was that it made one of the users clear minded and relaxed after taking it. It also significantly reduces semen volume. Many of the POISers here also have a very high libido, including me. I always wondered if a very high libido is a symptom of POIS, or if it is the other way around. I'm very casually thinking about trying something like this, but I wouldn't take such high doses that the users are taking over there, as I would want to lower my drive, not eliminate it. At the very least, it would reduce the amount of orgasms I have and allow me to abstain for way, way longer.

This is just a question and not a recommendation to anyone. Also, there are a few side effects such as hot flashes lower muscle density.

[Stef]

Hello All!

I haven't posted here in quite a while, but wanted to mention something that I hope you'll find encouraging regarding the NORD POIS research fund.  It occurred to me after receiving a question about the fund from an NSF forum member.

Your fund is well over $10,000 -- and very active.

I know that there was quite a bit of concern -- especially at first -- that your fund money could be moved to another fund if your goal wasn't met in a certain time. This is because our guidelines, posted on our website, state how and when funds are sometimes transferred -- something that we never, ever want to do -- and rarely have done (I mean RARELY!!) in the seven years that I've been administering the grant program.

We know that money donated to NORD for scientific research -- donated by individuals and/or groups for a particular rare disease -- is not just money.

Those donations represent  hope...and more importantly -- a real chance for a cure!

NORD's research grant program is not, and never will be, a lucrative program for NORD.  It was never meant to be a profit-maker, and was borne directly out of the desperation that people with rare disorders realistically feel.  The research has to begin with patient's donations -- it's the sad reality.

But the outcomes can -- -- and frequently have been -- WONDERFUL!! :-)
 
Our policy also states that the transfer of money is up to the discretion of NORD, which simply means that if there is interest expressed -- not even donations made -- genuine interest via emails or phone calls, inquiring about a particular fund -- we will not touch that fund.

Absolutely -- without question -- your POIS scientific research fund at NORD is 100% safe and sound.  Once a fund reaches $10,000 -- there is no way, whatsoever, that the funds will EVER be moved. You heard it here! :-)

That's A LOT OF MONEY for a beginning seed grant fund!!!!  If those of you who have pledged funds could meet those pledges -- you'd have an AMAZING research fund --> your first ever, scientifically sound and meaningful POIS research!

The minimum amount to post your grant (in March, 2013) is $33,500. You men (and any women who read this forum) would be crazy not to go for this!!!

In addition, the Indiegogo campaign to raise research funds for your NORD grant is just about ready to roll.  It will need your involvement! You'll be able to tell the world about this horrendous disorder, while raising money for solid, scientific research -- your ticket out of this nightmare.

And you may very well be saving the lives of others with POIS who happen onto the upcoming Indigogo POIS campaign -- they will find light and encouragement, instead of darkness and hopelessness.

You can read more about the POIS Indiegogo campaign at http://poiscenter.com/forums/index.php?topic=454.0 and  http://poiscenter.com/forums/index.php?topic=489.0.  It will likely be launched some time in the next two weeks -- so please do keep checking on it at those links.

EACH OF YOU CAN PLAY A VERY IMPORTANT ROLE IN THAT CAMPAIGN -- DON'T DOUBT IT FOR ONE MOMENT!

Wishing everyone the best -- and keep the faith!!

Stef

[kurtosis]

So I wonder if anyone has ever tried an anti-androgen. They're sometimes used by people who have a hair loss problem or who have severe acne, but a side effect is lower sex drive. I came across a site where they were talking about reducing their drive because some of them are orgasm addicts.(http://www.eunuch.org/forums/showthread.php?1018-30-Days-of-Androcur). One of the interesting things I read was that it made one of the users clear minded and relaxed after taking it. It also significantly reduces semen volume. Many of the POISers here also have a very high libido, including me. I always wondered if a very high libido is a symptom of POIS, or if it is the other way around. I'm very casually thinking about trying something like this, but I wouldn't take such high doses that the users are taking over there, as I would want to lower my drive, not eliminate it. At the very least, it would reduce the amount of orgasms I have and allow me to abstain for way, way longer.

This is just a question and not a recommendation to anyone. Also, there are a few side effects such as hot flashes lower muscle density.

It is interesting that Demografx has been "cured" effectively by testosterone patches which would have the opposite effect of an anti-androgen.

[martin88]

Absolutely -- without question -- your POIS scientific research fund at NORD is 100% safe and sound.  Once a fund reaches $10,000 -- there is no way, whatsoever, that the funds will EVER be moved. You heard it here! :-)

(I sent the PM)
That's very good to hear!
When I gave money at first, I thought even if it goes to other funds it's OK to help other causes, but that's why I didn't give more for now.
It's amazing to think we have 25000 (or more) with the pledges and 10000 in the fund.

[martin88]

So I wonder if anyone has ever tried an anti-androgen.

That's what Dr Waldinger was using at first to help POIS sufferers. I think he was using a small dose of flutamide but this should be confirmed.
 

[amijgoro]

amijgoro, what you are going through is pretty severe. Any physical contact to your penis!! I assume it has to be a stimulating sensation, and not just from even urinating. From what I read here foamy urine is not a typical pois symptom. In your case though the faulty plumbing seems to be causing a greater problem for you, combined with you being young with a hair trigger penis. So your urologist came up the 'shutter between the bladder and prostate doesn't shut tight enough' diagnosis. Can he operate to remedy this situation? That would be my first line of attack, given that there is no definitive cure on this site....though there have been a number of sufferers here recently who have made a lot of progress. You should read the posts from the past month especially, and try some of the supplements/meds.

I took to what my urologist said a little differently. What i understood from the meeting was because the shutter isn't tight enough and semen is leaking into my bladder and the overall fact that i have pois is the combination why i think im having these terrible symptoms. I searched the internet for some sort of medication/supplement that could possibly tighten the shutter and reverse the retrograde ejaculation. I found that sudafed a sinus and cold congestion relief medication has that exact effect. i tried out the sudafed and miraculously it worked! I didn't have that hair trigger penis anymore. the only problem was that the actual medication itself was making me feel very bad and brain fogged, an effect that has been haunting me with medication for a long time now (medication including ritalin and other anti depression/ anxiety drugs). my conclusion from that is 1. The problem is the shutter being week and semen leaking into my bladder that is causing the symptoms. 2. The pois that im experiencing understood by semen escaping the prostate being the cause of the symptoms mean that its the semen that is the problem! And thirdly my boddy has a serious problem regarding bad reactions to a large range of medications that needs an explanation.

Amigoro,
what are the ingredients of the Sudafet? Where I live we don't have Sudafet, but I can look for other cold congestion relief medication that has more or less the same ingredients. Many thanks!

I also have this "oil"on top of urine. And when I leave my first urine after ejaculation a night in a bottle, it has many white clouds in it.

The component in sudafed that tightens the sphincter is called Psuedoephedrine.
The med worked well with the original problem but gave me bad side effects (these side effects come about in many medications that I took in the past so don't dismiss it because of my personal body function).

The oil you describe floating on your pee I have too (I never let my pee sit overnight yet so I can't tell you if I have white clouds as well) both discribe semen in the urin.
This web site talks about different remedies that can help with retrograde ejaculation:

newbielink:http://www.mayoclinic.com/health/retrograde-ejaculation/DS00913/DSECTION=treatments-and-drugs [nonactive]

[Stef]

Once again, hello!

I've just been advised that the Indiegogo campaign is online now!!

Please go to www.indiegogo.com/research-for-POIS and check it out.  There are major ways that you can participate and make this campaign really successful. 

Daveman at poiscenter.com is the Team Leader if you have questions.

I'm wishing you all the best of luck with this fund raiser for your POIS research grant!

Stef

[Citizen A]

Hi everyone! I have had similar symptoms for couple of years now, in my case theyīre not so severe, usually lasting a day or two. I had anxiety attacs and insomnia before pois. For some reason I always thought, that its caused by something, thats eating my hormones and unbalancing me emotionally.
My profile (so You can compare possible factors) :
Im 36, started smoking and drinking when I was 13, now clean for 3,5 years, had allergies as a child and lots of antibiotic treatments against toncillitis. I have autoimmune disorder called lichen planus and nail fungus (both fingers and toes), that I ll try to treat, but because of my work in humid places and constant contact with wet gloves, is not that simple. I also have weak joints (fingers,elbows etc.) donīt know if it got anything to do with the matter. I dont drink coffee for same reason- its getting me hectic. Donīt eat sugar. I do drink milk. Have frequent eye -and headaches. Anyway, I have a theory, that the condition as pois is related to some bacteria or fungus (candida?), thats eating hormones and vital minerals and I agree, that its living possibly in our stomach (or brain?). I have had constipation for a long time. Im almost in constant stress, but its getting worse having O s, usually on second morning-having symptoms similar to hangover. Marijuana soothed the anxiety (tried it for a couple of months, after that it came back, maybe a bit worse), but Im sure, that its a two edged sword, and its not helping with the cause (I feel same way about vitamin /mineral supplements). And I think that pois is only indicating the problem as the act of having sex is comparable to any very hard physical/ emotional effort, that rushes your hormones. Going to a gym on a regular bases helped me too, but maybe it just boosted my testosterone level for that period of time- so the "enemy" had more to eat than it needed and leaved some of it to me (oh and I took some supplements too at that time) ... Im not a scientist so dont be harsh on my theories. And english isnīt my 1st language so give me some slack on my grammar too... Glad to find this conversation and hope that someone finds cure to this condition! Im also interested if someone have  conditions and/or observations similar to mine.

[acronym]

Citizen A - what interests me are the sufferers who got pois later in life. I had it pretty much when I started puberty. I think this is the case for the vast majority of guys here. With the few people who got it later in life, I would love to think it would be possible to trace back to a incident that triggered the change for them. So you got it around 34 and it seems after you started to clean up your health, which one would like to think would help to reduce pois. Anyway...your fungus theory...what evidence do you have to make you suspect this? Did you get the fungus growth/lichen planus for the first time a couple of years back?
Anything change in your life around 33-34 when you first started to get pois?